scholarly journals Elevated Neutrophil-to-Lymphocyte Ratio Predicts Depression After Intracerebral Hemorrhage

2020 ◽  
Vol Volume 16 ◽  
pp. 2153-2159
Author(s):  
Xiuqun Gong ◽  
Zeyu Lu ◽  
Xiwu Feng ◽  
Chuanqing Yu ◽  
Min Xue ◽  
...  
Stroke ◽  
2016 ◽  
Vol 47 (6) ◽  
pp. 1654-1657 ◽  
Author(s):  
Simona Lattanzi ◽  
Claudia Cagnetti ◽  
Leandro Provinciali ◽  
Mauro Silvestrini

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Fan Zhang ◽  
Yanming Ren ◽  
Wei Fu ◽  
Yuelong Wang ◽  
Juan Qian ◽  
...  

Abstract Previous studies indicated that both inflammatory responses and hyperglycemia are involved in the similar pathophysiological mechanisms after onset of intracerebral hemorrhage (ICH). However the relationship between hyperglycemia and inflammation remains unknown. We aim to evaluate the associations of hyperglycemia with inflammation and neutrophil to lymphocyte ratio (NLR) in patients with ICH. Patients with acute ICH were retrospectively enrolled. Clinical characteristics and imaging features were obtained. The associations between outcome and laboratory biomarkers were assessed by multivariable logistic regression analysis. Spearman analysis and multiple linear regression analysis were performed to estimate the association of NLR and serum glucose. 175 patients were enrolled. Poor outcome occurred in 86 patients at 30 days. Elevated blood glucose level (BGL) and NLR were strongly associated with outcome in patients with ICH. Moreover, combined NLR-BGL exhibited a better predictive accuracy compared with the peripheral leukocyte counts. Furthermore, there was a robust association between BGL and NLR. We first demonstrated both of NLR and BGL were independently associated with each other. Our results indicate that inflammatory responses and the pathological process of hyperglycemia may influence each other by several complex pathological mechanisms and have a mutual promoting effect to secondary brain injury.


2018 ◽  
Vol 387 ◽  
pp. 98-102 ◽  
Author(s):  
Simona Lattanzi ◽  
Claudia Cagnetti ◽  
Claudia Rinaldi ◽  
Stefania Angelocola ◽  
Leandro Provinciali ◽  
...  

2019 ◽  
Vol 25 (2) ◽  
pp. 118-124
Author(s):  
Mehmet Yasir Pektezel ◽  
Ethem Murat Arsava ◽  
Doğan Dinç Öge ◽  
Ozlem Kayim Yildiz ◽  
Mehmet Akif Topcuoglu

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