scholarly journals Early elevated neutrophil‐to‐lymphocyte ratio associated with remote diffusion‐weighted imaging lesions in acute intracerebral hemorrhage

2020 ◽  
Vol 26 (4) ◽  
pp. 430-437
Author(s):  
Jia‐Wen Li ◽  
Yu‐Yu Xu ◽  
Ye‐Jun Chen ◽  
Wei‐Wei Fan ◽  
Xu‐Hua Xu ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Diffusion Weighted Imaging ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Diffusion Weighted ◽  
Acute Intracerebral Hemorrhage

scholarly journals Neutrophil-to-Lymphocyte Ratio Predicts the Outcome of Acute Intracerebral Hemorrhage

Stroke ◽  
2016 ◽  
Vol 47 (6) ◽  
pp. 1654-1657 ◽  
Author(s):  
Simona Lattanzi ◽  
Claudia Cagnetti ◽  
Leandro Provinciali ◽  
Mauro Silvestrini
Keyword(s):  
Intracerebral Hemorrhage ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Acute Intracerebral Hemorrhage

Neutrophil-to-lymphocyte ratio improves outcome prediction of acute intracerebral hemorrhage

2018 ◽  
Vol 387 ◽  
pp. 98-102 ◽  
Author(s):  
Simona Lattanzi ◽  
Claudia Cagnetti ◽  
Claudia Rinaldi ◽  
Stefania Angelocola ◽  
Leandro Provinciali ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Outcome Prediction ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Acute Intracerebral Hemorrhage

Abstract 18: Diffusion Weighted Imaging Lesions in Patients With Acute Intracerebral Hemorrhage: A Pooled Analysis of Individual Patient Data From MISTIE-III, ATACH-II, I-DEF, and ERICH

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Santosh B Murthy ◽  
Sung-Min Cho ◽  
Ajay Gupta ◽  
Ashkan Shoamanesh ◽  
Radhika Avadhani ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Intracerebral Hemorrhage ◽  
Diffusion Weighted Imaging ◽  
Individual Patient Data ◽  
Mixed Effects ◽  
Patient Data ◽  
Factors Associated ◽  
Diffusion Weighted ◽  
Younger Age ◽  
Acute Intracerebral Hemorrhage

Introduction: The etiology and significance of diffusion weighted imaging (DWI) lesions in patients with acute intracerebral hemorrhage (ICH) remain unclear. We evaluated which factors were associated with DWI lesions, whether associated factors differed by ICH location, and whether DWI lesions were associated with functional outcomes. Methods: We pooled individual patient data from the MISTIE III trial, the ATACH-II trial, the i-DEF trial, and the ERICH study. We included only patients who underwent protocolized magnetic resonance imaging (MRI) of the brain. A poor functional outcome was defined as a modified Rankin Scale (mRS) score of 4-6 at 3-6 months. We used mixed effects logistic regression with the study database as a random effect. Results: Among 1,775 ICH patients, there were 621 (35.6%) lobar, 978 (55.9%) deep, and 148 (8.5%) infratentorial ICHs. Median time to MRI scan was 1.5 days (IQR, 1-4). DWIHLs occurred in 559 (31.5%) patients, with 190 (34.3%) in lobar ICH and 320 (57.8%) in deep ICHs. In mixed effects regression models, factors associated with DWIHLs included younger age factors associated with DWIHLs after acute ICH included younger age (OR, 0.98; 95% CI, 0.97-0.99), black race (OR, 1.59; 95% CI, 1.18-2.16), admission systolic blood pressure (SBP per 10 mm Hg, OR, 1.13; 95% CI, 1.05-1.22), cerebral microbleeds (OR, 1.71, 95% CI, 1.24-2.35), and leukoaraiosis (OR, 1.60; 95% CI, 1.14-2.25). Patients with DWIHLs had higher odds of mRS 4-6 (OR, 1.57; 95% CI, 1.24-1.99) compared to those without, after adjustment for demographics and ICH severity. In subgroup analyses, similar factors influenced DWIHLs in deep ICH. However, in lobar ICH, younger age, admission SBP, and leukoaraiosis were associated with DWIHLs. Presence of DWIHLs was independently associated with poor mRS in deep ICH but not in lobar ICH. There was no relationship between acute BP lowering and DWIHLs, regardless of location. Conclusions: In a large, heterogeneous cohort of ICH patients, our results are consistent with the hypothesis that DWIHLs represent the effects of chronic hypertensive vasculopathy and acute blood pressure elevation. Furthermore, DWIHLs portend poor prognosis after ICH, particularly in deep hemorrhages.

scholarly journals Diffusion-Weighted Imaging Hyperintensities in Subtypes of Acute Intracerebral Hemorrhage

Stroke ◽  
2019 ◽  
Vol 50 (1) ◽  
pp. 135-142 ◽  
Author(s):  
Marion Boulanger ◽  
Romain Schneckenburger ◽  
Claire Join-Lambert ◽  
David J. Werring ◽  
Duncan Wilson ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Diffusion Weighted Imaging ◽  
Diffusion Weighted ◽  
Acute Intracerebral Hemorrhage

scholarly journals A Pooled Analysis of Diffusion-Weighted Imaging Lesions in Patients With Acute Intracerebral Hemorrhage

2020 ◽  
Vol 77 (11) ◽  
pp. 1390
Author(s):  
Santosh B. Murthy ◽  
Sung-Min Cho ◽  
Ajay Gupta ◽  
Ashkan Shoamanesh ◽  
Babak B. Navi ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Diffusion Weighted Imaging ◽  
Pooled Analysis ◽  
Diffusion Weighted ◽  
Acute Intracerebral Hemorrhage
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