scholarly journals Associations Between Gut Microbiota and Asthma Endotypes: A Cross-Sectional Study in South China Based on Patients with Newly Diagnosed Asthma

2021 ◽  
Vol Volume 14 ◽  
pp. 981-992
Author(s):  
Xiao-Ling Zou ◽  
Jin-Jie Wu ◽  
Hui-Xia Ye ◽  
Ding-Yun Feng ◽  
Ping Meng ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
South China ◽  
Cross Sectional Study ◽  
Newly Diagnosed ◽  
Sectional Study ◽  
Cross Sectional

Gut microbiota in patients with newly diagnosed acromegaly: a pilot cross-sectional study

Pituitary ◽  
2021 ◽  
Author(s):  
Aysa Hacioglu ◽  
◽  
Aycan Gundogdu ◽  
Ufuk Nalbantoglu ◽  
Zuleyha Karaca ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Cross Sectional Study ◽  
Newly Diagnosed ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Gut Microbiota Profile and Its Association with Clinical Variables and Dietary Intake in Overweight/Obese and Lean Subjects: A Cross-Sectional Study

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 2032
Author(s):  
Judit Companys ◽  
Maria José Gosalbes ◽  
Laura Pla-Pagà ◽  
Lorena Calderón-Pérez ◽  
Elisabet Llauradó ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Dietary Intake ◽  
Saturated Fatty Acids ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Anthropometric Parameters ◽  
Cross Sectional ◽  
Negatively Associated ◽  
Clinical Variables ◽  
Obese Subjects

We aimed to differentiate gut microbiota composition of overweight/obese and lean subjects and to determine its association with clinical variables and dietary intake. A cross-sectional study was performed with 96 overweight/obese subjects and 32 lean subjects. Anthropometric parameters were positively associated with Collinsella aerofaciens, Dorea formicigenerans and Dorea longicatena, which had higher abundance the overweight/obese subjects. Moreover, different genera of Lachnospiraceae were negatively associated with body fat, LDL and total cholesterol. Saturated fatty acids (SFAs) were negatively associated with the genus Intestinimonas, a biomarker of the overweight/obese group, whereas SFAs were positively associated with Roseburia, a biomarker for the lean group. In conclusion, Dorea formicigenerans, Dorea longicatena and Collinsella aerofaciens could be considered obesity biomarkers, Lachnospiraceae is associated with lipid cardiovascular risk factors. SFAs exhibited opposite association profiles with butyrate-producing bacteria depending on the BMI. Thus, the relationship between diet and microbiota opens new tools for the management of obesity.

scholarly journals The characteristics of newly diagnosed adult early-onset diabetes: a population-based cross-sectional study

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Xiantong Zou ◽  
Xianghai Zhou ◽  
Linong Ji ◽  
Wenying Yang ◽  
Juming Lu ◽  
...  
Keyword(s):  
Early Onset ◽  
Population Based ◽  
Cross Sectional Study ◽  
Newly Diagnosed ◽  
Sectional Study ◽  
Cross Sectional ◽  
Onset Diabetes

scholarly journals Association of faecal pH with childhood stunting: Results from a cross-sectional study

2019 ◽  
Vol 3 (1) ◽  
pp. e000549 ◽  
Author(s):  
Md. Shabab Hossain ◽  
Subhasish Das ◽  
Md. Amran Gazi ◽  
Md. Ashraful Alam ◽  
Nur Muhammad Shahedul Haque ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Linear Growth ◽  
Pearson Correlation ◽  
Cross Sectional Study ◽  
Inverse Association ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Faecal Ph ◽  
Childhood Stunting

BackgroundGut microbiota plays an important role in the growth of children. The gut of children with optimum growth is enriched in certain species, especially Bifidobacteria and Clostridia. Bifidobacteria and commensal Clostridia both contribute to formation of acidic stool, and an elevated faecal pH indicates reduction of these species in the gut. The purpose of the study was to investigate the association of faecal pH with childhood stunting.MethodsIn this cross-sectional study, 100 children with length-for-age Z score (LAZ) <−1 aged between 12 and 18 months were enrolled from the ongoing Bangladesh Environmental Enteric Dysfunction study conducted in Dhaka, Bangladesh. LAZ was measured by anthropometry and data on factors affecting linear growth were recorded. Faecal pH measurement was done using pH metre on freshly collected non-diarrhoeal faecal samples following standard procedure. Multiple quantile regression was done to quantify the relation between faecal pH and LAZ scores.ResultsThe mean LAZ and faecal pH of the children were −2.12±0.80 and 5.84±1.11, respectively. Pearson correlation analysis showed a statistically significant negative correlation between stool pH and the LAZ scores (p<0.01). After inclusion of other factors affecting linear growth into the regression model, a statistically significant inverse association was observed between faecal pH and LAZ score (p<0.01).ConclusionElevated faecal pH was found to have a significant association with stunted growth. As an indicator of gut microbiota status, faecal pH might have emerged as a possible indirect determinant of childhood stunting.Trial registration numberNCT02812615

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