scholarly journals Association Between Bipolar Disorder and Low Bone Mass: A Cross-Sectional Study With Newly Diagnosed, Drug-Naïve Patients

2020 ◽  
Vol 11 ◽  
Author(s):  
Sujuan Li ◽  
Yan Qui ◽  
Ziwei Teng ◽  
Jindong Chen ◽  
Dongyu Kang ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Bone Mass ◽  
Cross Sectional Study ◽  
Newly Diagnosed ◽  
Low Bone Mass ◽  
Sectional Study ◽  
Cross Sectional ◽  
Drug Naïve

scholarly journals Association between Hypertension, Antihypertensive Drugs, and Osteoporosis in Postmenopausal Syrian Women: A Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-6 ◽  
Author(s):  
Nermeen Hijazi ◽  
Zaynab Alourfi
Keyword(s):  
Bone Mineral Density ◽  
Bone Mass ◽  
Bone Mineral ◽  
Antihypertensive Drugs ◽  
Cross Sectional Study ◽  
World Health ◽  
Low Bone Mass ◽  
Sectional Study ◽  
Mineral Density ◽  
Cross Sectional

Background. Osteoporosis and hypertension are frequent and often coexisting diseases among the elderly. Recent studies suggested that both diseases may share the same etiopathology. Moreover, the treatment of hypertension can affect the bone mineral density and worsen osteoporosis. The aim of this cross-sectional study was to assess the prevalence of low bone mass and osteoporosis in postmenopausal Syrian women and investigate their relationship with hypertension and antihypertensive drugs. Methods. 813 postmenopausal women were involved in this cross-sectional study, aged between 40 and 96 yrs. Their menopause duration ranged between 1 and 43 yrs. Bone mineral density was measured using a dual-energy X-ray absorptiometry at the total lumbar spine (L1-L4) and left hip. T-score values were used to determine the diagnosis of osteoporosis. The existence of HTN was defined as blood pressure ≥130/85 mmHg or a history of hypertension medication. Results. Using the world health organization criteria, 24% had osteoporosis and 45.2% had low bone mass. The incidence of osteoporosis and low bone mass significantly increased with age and menopause duration and decreased with BMI. Prevalence of hypertension was almost equal among the women who had or did not have osteoporosis. However, hypertensive women who used thiazides or beta blockers had higher values of total lumbar BMD compared with the women who did not. Conclusion. Hypertension in postmenopausal Syrian women aged over 40 was not found to be associated with osteoporosis. However, the mean total lumbar BMD of the hypertensive women who took thiazide diuretics or beta blocker was found to be increased significantly comparing to the women who did not take either.

scholarly journals Association between low bone mass and calcium and caffeine intake among perimenopausal women in Southern Brazil: cross-sectional study

2013 ◽  
Vol 131 (5) ◽  
pp. 315-322 ◽  
Author(s):  
Daniele Lazzarotto Harter ◽  
Fernanda Michielin Busnello ◽  
Raquel Papandreus Dibi ◽  
Airton Tetelbom Stein ◽  
Sergio Kakuta Kato ◽  
...  
Keyword(s):  
Bone Mass ◽  
Calcium Intake ◽  
Cross Sectional Study ◽  
Caffeine Intake ◽  
Southern Brazil ◽  
Low Bone Mass ◽  
Sectional Study ◽  
Cross Sectional ◽  
Modifiable Factors ◽  
Perimenopausal Women

CONTEXT AND OBJECTIVE: Osteoporosis is a skeletal abnormality characterized by reduction and alteration of bone microarchitecture that results in increased fragility and greater predisposition to fractures. Age and low bone mass are the main non-modifiable risk factors for osteoporotic fractures. The modifiable factors include sedentary lifestyle, inadequate calcium intake, excessive alcohol and/or caffeine consumption, smoking and low body weight. The aim here was to evaluate the association between low bone mass and calcium and caffeine intake among perimenopausal women in Southern Brazil. DESIGN AND SETTING: Cross-sectional study conducted in Porto Alegre and Canoas, Rio Grande do Sul, Brazil. METHODS: Women (n = 155) of mean age 53.6 ± 9.5 years were evaluated through a cross-sectional study in Southern Brazil. Food frequency questionnaires, bone mass evaluation using calcaneal ultrasound and anthropometric assessment were used. RESULTS: The prevalence of overweight was 67.7%. In the bone mass screening, 30.3% had low bone mass and 4.5% had osteoporosis. The median calcium intake was 574.94 mg/day and the caffeine intake was 108.11 mg/day. No association was found between bone mass and anthropometric parameters, calcium intake or caffeine intake. It was found that 38.4% of the women had low bone mass. CONCLUSIONS: No association was found between calcium and caffeine intake and bone mass. High prevalence of low bone mass was observed.

scholarly journals Magnitude of internalised stigma and associated factors among people with bipolar disorder at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia: a cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. e044824
Author(s):  
Shegaye Shumet ◽  
Bethlehem W/Michele ◽  
Dessie Angaw ◽  
Temesgen Ergete ◽  
Nigus Alemnew
Keyword(s):  
Social Support ◽  
Bipolar Disorder ◽  
Associated Factors ◽  
Addis Ababa ◽  
Self Esteem ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Specialized Hospital ◽  
Poor Social Support

ObjectivesTo assess the magnitude of internalised stigma and associated factors among patients with bipolar disorder attending the outpatient department of Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia.DesignInstitution-based cross-sectional study design.SettingAmanuel Mental Specialized Hospital, Addis Ababa, Ethiopia.ParticipantsWe recruited about 418 participants using systematic sampling technique for an interview during the study period.MeasurementData were collected by face-to-face interviews. Internalized Stigma of Mental Illness scale was used to measure internalised stigma. The Rosenberg Self-Esteem Scale and the Oslo-3 Social Support were instruments used to assess the associated factors. Bivariate and multivariate logistic regressions were performed to identify factors associated with the outcome variable. ORs with 95% CI were computed to determine the level of significance.ResultsThe magnitude of internalised stigma was 24.9% (95% CI: 21.2% to 28.9%). In the multivariate analysis, unemployed (adjusted OR (AOR)=2.3, 95% CI: 1.0 to 5.0), unable to read and write (AOR=3.3, 95% CI: 1.05 to 10.7), poor social support (AOR=5.3, 95% CI: 1.9 to 15.0), ≥4 previous hospitalisations due to bipolar disorder (AOR=2.6, 95% CI: 1.1 to 6.1) and low self-esteem (AOR=2.4, 95% CI: 1.1 to 5.1) had a significant association with internalised stigma.ConclusionsOne in four patients with bipolar disorder reported high internalised stigma. Unemployment, low educational status, low self-esteem, poor social support and being hospitalised more than three times before were significantly associated with internalised stigma. Thus, a stigma-reduction programme focusing on self-esteem improvement and psychological health of patients to increase their stigma resistance to counteracting effects of internalised stigma is essential.

Gut microbiota in patients with newly diagnosed acromegaly: a pilot cross-sectional study

Pituitary ◽  
2021 ◽  
Author(s):  
Aysa Hacioglu ◽  
◽  
Aycan Gundogdu ◽  
Ufuk Nalbantoglu ◽  
Zuleyha Karaca ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Cross Sectional Study ◽  
Newly Diagnosed ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals The characteristics of newly diagnosed adult early-onset diabetes: a population-based cross-sectional study

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Xiantong Zou ◽  
Xianghai Zhou ◽  
Linong Ji ◽  
Wenying Yang ◽  
Juming Lu ◽  
...  
Keyword(s):  
Early Onset ◽  
Population Based ◽  
Cross Sectional Study ◽  
Newly Diagnosed ◽  
Sectional Study ◽  
Cross Sectional ◽  
Onset Diabetes

scholarly journals Cardiometabolic disease and features of depression and bipolar disorder: Population-based, cross-sectional study

2016 ◽  
Vol 208 (4) ◽  
pp. 343-351 ◽  
Author(s):  
Daniel J. Martin ◽  
Zia Ul-Haq ◽  
Barbara I. Nicholl ◽  
Breda Cullen ◽  
Jonathan Evans ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Bipolar Disorder ◽  
Mood Disorder ◽  
Psychotropic Medication ◽  
Large Population ◽  
Population Sample ◽  
Cross Sectional Study ◽  
Cardiometabolic Disease ◽  
Sectional Study ◽  
Cross Sectional

BackgroundThe relative contribution of demographic, lifestyle and medication factors to the association between affective disorders and cardiometabolic diseases is poorly understood.AimsTo assess the relationship between cardiometabolic disease and features of depresion and bipolar disorder within a large population sample.MethodCross-sectional study of 145 991 UK Biobank participants: multivariate analyses of associations between features of depression or bipolar disorder and five cardiometabolic outcomes, adjusting for confounding factors.ResultsThere were significant associations between mood disorder features and ‘any cardiovascular disease’ (depression odds ratio (OR) = 1.15, 95% CI 1.12–1.19; bipolar OR = 1.28, 95% CI 1.14–1.43) and with hypertension (depression OR = 1.15, 95% CI 1.13–1.18; bipolar OR = 1.26, 95% CI 1.12–1.42). Individuals with features of mood disorder taking psychotropic medication were significantly more likely than controls not on psychotropics to report myocardial infarction (depression OR = 1.47, 95% CI 1.24–1.73; bipolar OR = 2.23, 95% CI 1.53–3.57) and stroke (depression OR = 2.46, 95% CI 2.10–2.80; bipolar OR = 2.31, 95% CI 1.39–3.85).ConclusionsAssociations between features of depression or bipolar disorder and cardiovascular disease outcomes were statistically independent of demographic, lifestyle and medication confounders. Psychotropic medication may also be a risk factor for cardiometabolic disease in individuals without a clear history of mood disorder.

scholarly journals Associations between residual depressive symptoms, cognition, and functioning in patients with euthymic bipolar disorder: results from the FACE-BD cohort

2017 ◽  
Vol 211 (6) ◽  
pp. 381-387 ◽  
Author(s):  
Paul Roux ◽  
Aurélie Raust ◽  
Anne-Sophie Cannavo ◽  
Valérie Aubin ◽  
Bruno Aouizerate ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Depressive Symptoms ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cognitive Component ◽  
Cognitive Components ◽  
The Face ◽  
Sources Of Variation ◽  
The Relationship

BackgroundThe relationship between residual depressive symptoms, cognition and functioning in patients with euthymic bipolar disorder is a subject of debate.AimsTo assess whether cognition mediates the association between residual depressive symptoms and functioning in patients with bipolar disorder who were euthymic.MethodWe included 241 adults with euthymic bipolar disorder in a multicentre cross-sectional study. We used a battery of tests to assess six cognition domains. A path analysis was then used to perform a mediation analysis of the relationship between residual depressive symptoms, cognitive components and functioning.ResultsOnly verbal and working memory were significantly associated with better functioning. Residual depressive symptoms were associated with poorer functioning. No significant relationship was found between residual depressive symptoms and any cognitive component.ConclusionsCognition and residual depressive symptoms appear to be two independent sources of variation in the functioning of people with euthymic bipolar disorder.

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