scholarly journals Detection of gold nanorods uptake by macrophages using scattering analyses combined with diffusion reflection measurements as a potential tool for in vivo atherosclerosis tracking

2015 ◽  
pp. 4437 ◽  
Author(s):  
Dror Fixler ◽  
Rinat Ankri ◽  
Attila Tarnok ◽  
Susanne Melzer
Keyword(s):  
Gold Nanorods ◽  
Diffusion Reflection ◽  
Potential Tool

Hyperlipidemic mice as a model for a real-time in vivo detection of atherosclerosis by gold nanorods-based diffusion reflection technique

2018 ◽  
Vol 12 (1) ◽  
pp. e201800218 ◽  
Author(s):  
Ruchira Chakraborty ◽  
Rinat Ankri ◽  
Dorit Leshem-Lev ◽  
Edith Hochhauser ◽  
Ran Kornowski ◽  
...  
Keyword(s):  
Real Time ◽  
Gold Nanorods ◽  
In Vivo Detection ◽  
Diffusion Reflection

In-vivo Tumor detection using diffusion reflection measurements of targeted gold nanorods - a quantitative study

2012 ◽  
Vol 5 (3) ◽  
pp. 263-273 ◽  
Author(s):  
Rinat Ankri ◽  
Hamootal Duadi ◽  
Menachem Motiei ◽  
Dror Fixler
Keyword(s):  
Quantitative Study ◽  
Gold Nanorods ◽  
Tumor Detection ◽  
Diffusion Reflection

scholarly journals Proteomic analysis of silica hybrid sol-gel coatings: a potential tool for predicting the biocompatibility of implants in vivo

Biofouling ◽  
2017 ◽  
Vol 33 (8) ◽  
pp. 676-689 ◽  
Author(s):  
F. Romero-Gavilan ◽  
A. M. Sánchez-Pérez ◽  
N. Araújo-Gomes ◽  
M. Azkargorta ◽  
I. Iloro ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Sol Gel ◽  
Potential Tool ◽  
Silica Hybrid

In-vivo ultrasound and photoacoustic image- guided photothermal cancer therapy using silica-coated gold nanorods

2014 ◽  
Vol 61 (5) ◽  
pp. 891-897 ◽  
Author(s):  
Seungsoo Kim ◽  
Yun-sheng Chen ◽  
Geoffrey P. Luke ◽  
Stanislav Y. Emelianov
Keyword(s):  
Cancer Therapy ◽  
Gold Nanorods ◽  
Image Guided

In Vivo Monitoring of Intravenously Injected Gold Nanorods Using Near‐Infrared Light

Small ◽  
2008 ◽  
Vol 4 (7) ◽  
pp. 1001-1007 ◽  
Author(s):  
Takuro Niidome ◽  
Yasuyuki Akiyama ◽  
Kohei Shimoda ◽  
Takahito Kawano ◽  
Takeshi Mori ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
In Vivo Monitoring

Polymeric/Inorganic Multifunctional Nanoparticles for Simultaneous Drug Delivery and Visualization

2010 ◽  
Vol 1257 ◽  
Author(s):  
Andrea Fornara ◽  
Alberto Recalenda ◽  
Jian Qin ◽  
Abhilash Sugunan ◽  
Fei Ye ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Fluorescence Microscopy ◽  
Contrast Agents ◽  
Gold Nanorods ◽  
In Vitro Cytotoxicity ◽  
In Vivo Studies ◽  
Multifunctional Nanoparticles ◽  
Cytotoxicity Studies

AbstractNanoparticles consisting of different biocompatible materials are attracting a lot of interest in the biomedical area as useful tools for drug delivery, photo-therapy and contrast enhancement agents in MRI, fluorescence and confocal microscopy. This work mainly focuses on the synthesis of polymeric/inorganic multifunctional nanoparticles (PIMN) based on biocompatible di-block copolymer poly(L,L-lactide-co-ethylene glycol) (PLLA-PEG) via an emulsion-evaporation method. Besides containing a hydrophobic drug (Indomethacin), these polymeric nanoparticles incorporate different visualization agents such as superparamagnetic iron oxide nanoparticles (SPION) and fluorescent Quantum Dots (QDs) that are used as contrast agents for Magnetic Resonance Imaging (MRI) and fluorescence microscopy together. Gold Nanorods are also incorporated in such nanostructures to allow simultaneous visualization and photodynamic therapy. MRI studies are performed with different loading of SPION into PIMN, showing an enhancement in T2 contrast superior to commercial contrast agents. Core-shell QDs absorption and emission spectra are recorded before and after their loading into PIMN. With these polymeric/inorganic multifunctional nanoparticles, both MRI visualization and confocal fluorescence microscopy studies can be performed. Gold nanorods are also synthesized and incorporated into PIMN without changing their longitudinal absorption peak usable for lased excitation and phototherapy. In-vitro cytotoxicity studies have also been performed to confirm the low cytotoxicity of PIMN for further in-vivo studies.

scholarly journals In Vivo Neocortical [K]o Modulation by Targeted Stimulation of Astrocytes

2021 ◽  
Vol 22 (16) ◽  
pp. 8658
Author(s):  
Azin EbrahimAmini ◽  
Shanthini Mylvaganam ◽  
Paolo Bazzigaluppi ◽  
Mohamad Khazaei ◽  
Alexander Velumian ◽  
...  
Keyword(s):  
Nervous System ◽  
Membrane Potential ◽  
Potassium Ion ◽  
Ion Concentration ◽  
Extracellular Potassium ◽  
Spreading Depolarization ◽  
Potential Tool ◽  
Stimulation Of

A normally functioning nervous system requires normal extracellular potassium ion concentration ([K]o). Throughout the nervous system, several processes, including those of an astrocytic nature, are involved in [K]o regulation. In this study we investigated the effect of astrocytic photostimulation on [K]o. We hypothesized that in vivo photostimulation of eNpHR-expressing astrocytes leads to a decreased [K]o. Using optogenetic and electrophysiological techniques we showed that stimulation of eNpHR-expressing astrocytes resulted in a significantly decreased resting [K]o and evoked K responses. The amplitude of the concomitant spreading depolarization-like events also decreased. Our results imply that astrocytic membrane potential modification could be a potential tool for adjusting the [K]o.

Smart assembly of Mn-ferrites/silica core–shell with fluorescein and gold nanorods: robust and stable nanomicelles for in vivo triple modality imaging

2018 ◽  
Vol 6 (19) ◽  
pp. 2993-2999 ◽  
Author(s):  
Ilaria Monaco ◽  
Paolo Armanetti ◽  
Erica Locatelli ◽  
Alessandra Flori ◽  
Mirko Maturi ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Core Shell ◽  
Smart Assembly ◽  
Silica Core

We report the synthesis of a resilient nanosystem (MnFe2O4@SiO2@GNRs@PMs) for magnetic–photoacoustic–optical triple-modality imaging.

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