scholarly journals Efficient gene delivery system mediated by cis-aconitate-modified chitosan-g-stearic acid micelles

2014 ◽  
pp. 2993 ◽  
Author(s):  
Fu-Qiang Hu ◽  
Jing-Jing Yao ◽  
Yong-Zhong Du ◽  
Jian You ◽  
Hong Yuan
Keyword(s):  
Gene Delivery ◽  
Stearic Acid ◽  
Delivery System ◽  
Gene Delivery System ◽  
Modified Chitosan ◽  
Efficient Gene

scholarly journals Echogenic PEGylated PEI-Loaded Microbubble As Efficient Gene Delivery System

2019 ◽  
Vol Volume 14 ◽  
pp. 8923-8941 ◽  
Author(s):  
Chun Liufu ◽  
Yue Li ◽  
Jiawei Tu ◽  
Hui Zhang ◽  
Jinsui Yu ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Delivery System ◽  
Gene Delivery System ◽  
System P ◽  
Efficient Gene

Dual-functionalized calcium carbonate based gene delivery system for efficient gene delivery

RSC Advances ◽  
2014 ◽  
Vol 4 (73) ◽  
pp. 38623-38629 ◽  
Author(s):  
Chao-Qun Wang ◽  
Meng-Qing Gong ◽  
Jin-Long Wu ◽  
Ren-Xi Zhuo ◽  
Si-Xue Cheng
Keyword(s):  
Calcium Carbonate ◽  
Gene Delivery ◽  
Delivery System ◽  
Gene Transfection ◽  
Cell Penetrating Peptide ◽  
Gene Delivery System ◽  
Dna Nanoparticles ◽  
Efficient Gene ◽  
Cell Penetrating ◽  
A Cell

Dual-functionalized KALA/PS/CaCO3/DNA nanoparticles containing a cell penetrating peptide (KALA) and protamine sulfate (PS) could effectively mediate gene transfection at a low DNA concentration.

scholarly journals Local Gene Delivery System by Bubble Liposomes and Ultrasound Exposure into Joint Synovium

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Yoichi Negishi ◽  
Yuka Tsunoda ◽  
Yoko Endo-Takahashi ◽  
Yusuke Oda ◽  
Ryo Suzuki ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Transfer ◽  
Gene Delivery ◽  
Delivery System ◽  
Imaging System ◽  
Effective Means ◽  
Gene Delivery System ◽  
Highly Efficient ◽  
Efficient Gene

Recently, we have developed novel polyethylene glycol modified liposomes (bubble liposomes; BL) entrapping an ultrasound (US) imaging gas, which can work as a gene delivery tool with US exposure. In this study, we investigated the usefulness of US-mediated gene transfer systems with BL into synoviocytes in vitro and joint synovium in vivo. Highly efficient gene transfer could be achieved in the cultured primary synoviocytes transfected with the combination of BL and US exposure, compared to treatment with plasmid DNA (pDNA) alone, pDNA plus BL, or pDNA plus US. When BL was injected into the knee joints of mice, and US exposure was applied transcutaneously to the injection site, highly efficient gene expression could be observed in the knee joint transfected with the combination of BL and US exposure, compared to treatment with pDNA alone, pDNA plus BL, or pDNA plus US. The localized and prolonged gene expression was also shown by an in vivo luciferase imaging system. Thus, this local gene delivery system into joint synovium using the combination of BL and US exposure may be an effective means for gene therapy in joint disorders.

Development of a safe and efficient gene delivery system based on a biodegradable tannic acid backbone

2019 ◽  
Vol 183 ◽  
pp. 110408
Author(s):  
Shuheng Wu ◽  
Yujian Yan ◽  
Dani Ni ◽  
Xianhu Pan ◽  
Xin Chen ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Tannic Acid ◽  
Delivery System ◽  
Gene Delivery System ◽  
Efficient Gene

An efficient gene delivery system into cells using a nano-size silicon needle

2007 ◽  
Vol 58 ◽  
pp. S242 ◽  
Author(s):  
Chikako Hara ◽  
Kiyohiko Tateyama ◽  
Hideyuki Okano ◽  
Atsushi Miyawaki
Keyword(s):  
Gene Delivery ◽  
Delivery System ◽  
Gene Delivery System ◽  
Efficient Gene ◽  
Nano Size

Construction of traceable cucurbit[7]uril-based virus-mimicking quaternary complexes with aggregation-induced emission for efficient gene transfection

2020 ◽  
Vol 8 (33) ◽  
pp. 7475-7482
Author(s):  
De-E Liu ◽  
Xiangjie Yan ◽  
Jinxia An ◽  
Jianbiao Ma ◽  
Hui Gao
Keyword(s):  
Gene Delivery ◽  
Delivery System ◽  
Gene Transfection ◽  
Delivery Systems ◽  
Endosomal Escape ◽  
Gene Delivery System ◽  
Aggregation Induced Emission ◽  
Efficient Gene ◽  
Novel Virus

A novel virus-mimicking gene delivery system with excellent endosomal escape, efficient transfection, and traceability is developed which can serve as a reference for the construction of novel multifunctional efficient gene delivery systems.

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