scholarly journals Green Synthesis of Fe3O4 Nanoparticles Stabilized by a Garcinia mangostana Fruit Peel Extract for Hyperthermia and Anticancer Activities

2021 ◽  
Vol Volume 16 ◽  
pp. 2515-2532
Author(s):  
Mostafa Yusefi ◽  
Kamyar Shameli ◽  
Ong Su Yee ◽  
Sin-Yeang Teow ◽  
Ziba Hedayatnasab ◽  
...  
2021 ◽  
Vol 212 ◽  
pp. 368-375
Author(s):  
Abdul Ghaffar ◽  
◽  
Shumaila Kiran ◽  
Muhammad Asim Rafique ◽  
Sarosh Iqbal ◽  
...  

IRC-SET 2018 ◽  
2019 ◽  
pp. 9-23
Author(s):  
Clyve Yu Leon Yaow ◽  
Ian Ee En Sim ◽  
Feldman Kuan Ming Lee ◽  
Doreen Wei Ying Yong ◽  
Wee Shong Chin

Nanomaterials ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 1423 ◽  
Author(s):  
Kar Xin Lee ◽  
Kamyar Shameli ◽  
Shaza Eva Mohamad ◽  
Yen Pin Yew ◽  
Eleen Dayana Mohamed Isa ◽  
...  

Discovery of a potent drug nanocarrier is crucial for cancer therapy in which drugs often face challenges in penetrating efficiently into solid tumours. Here, biosynthesis of silver nanoparticles (AgNPs) using a waste material, Garcinia mangostana (GM) fruit peel extract is demonstrated. The best condition for AgNPs synthesis was with 0.5 g of peel extract, 7.5 mM silver nitrate at 45 °C, ~pH 4 for 16 h. The synthesized AgNPs were spherical and 32.7 ± 5.7 nm in size. To test its efficiency to be used as drug carrier, plant-based drug, protocatechuic acid (PCA) was used as a test drug. AgNPs loaded with PCA (AgPCA) resulted in 80% of inhibition at 15.6 µg/mL as compared to AgNPs which only killed 5% of HCT116 colorectal cells at same concentration. The IC50 of AgNPs and AgPCA for HCT116 were 40.2 and 10.7 µg/mL, respectively. At 15.6 µg/mL, AgPCA was not toxic to the tested colon normal cells, CCD112. Ag-based drug carrier could also potentially reduce the toxicity of loaded drug as the IC50 of PCA alone (148.1 µg/mL) was higher than IC50 of AgPCA (10.7 µg/mL) against HCT116. Further, 24-h treatment of 15.6 µg/mL AgPCA resulted in loss of membrane potential in the mitochondria of HCT116 cells and increased level of reaction oxygen species (ROS). These could be the cellular killing mechanisms of AgPCA. Collectively, our findings show the synergistic anticancer activity of AgNPs and PCA, and its potential to be used as a potent anticancer drug nanocarrier.


Author(s):  
Rajni Garg ◽  
Mamta Kumari ◽  
Mandeep Kumar ◽  
Sourabh Dhiman ◽  
Rishav Garg

RSC Advances ◽  
2020 ◽  
Vol 10 (40) ◽  
pp. 23899-23907 ◽  
Author(s):  
Tu Uyen Doan Thi ◽  
Trung Thoai Nguyen ◽  
Y Dang Thi ◽  
Kieu Hanh Ta Thi ◽  
Bach Thang Phan ◽  
...  

This paper presents an efficient, environmentally friendly, and simple approach for the green synthesis of ZnO nanoparticles (ZnO NPs) using orange fruit peel extract.


2021 ◽  
Vol 1 (1) ◽  
pp. 53-61
Author(s):  
Mostafa Yusefi ◽  
Ong Su Yee ◽  
Kamyar Shameli

The overwhelming request for nanodevices and heat flow developments has led to consider magnetic Fe3O4 nanoparticles as a new dawn to the sophisticated nanotechnology in a sustainable manner. This research presented a facile production of Fe3O4 nanoparticles using co-precipitation method and the extract of Garcinia Mangostana fruit peel waste as a green stabilizer and capping agent. The X-ray powder diffraction (XRD) planes of the synthesized nanoparticles showed the formation of magnetite Fe3O4 nanoparticles with good crystallinity. Based on the image of field emission scanning electron microscope (FESEM), the diameter of the nanoparticles was estimated to be 69.14±2.87 nm as was coated by the extract. The Fe3O4 nanoparticles presented an acceptable magnetization value of 51.17 emu/g. From the analysis of Fourier-transform infrared spectroscopy (FTIR), the phenolic compounds and other functional groups of the extract had interactions with the Fe ions to successfully synthesize the nanoparticles. The green synthesized Fe3O4 nanofluids showed small hydrodynamic size of 145.80±3.14 and high zeta potential value of -30.5±1.82 mV. This study, thus, showed that the extract of Garcinia Mangostana fruit peel waste can serve as a bio-stabilizer and capping agent to enhance physiochemical properties and colloidal stability of the Fe3O4 nanofluids with an environmentally-friendly manner and low cost for modern applications.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
M. Sivakavinesan ◽  
M. Vanaja ◽  
G. Annadurai

AbstractThe present work aimed at synthesizing gold nanoparticles in a biological method employing fruit peel waste dumped in the environment. The peels of Garcinia mangostana (Mangostan), were collected from the nearby tourist spot during the season. The collected fruit peels were washed, dried, powder and extracted by using boiling water and acetone. The precipitated extract was dried and powdered for further use. The dried and powdered peel extract was added to the gold solution and boiled to 80 °C and the color change is observed. The color change indicates the completion of the synthesis of gold nanoparticles. The effect of pH, gold ion concentration, peel extract powder concentration, and the temperature was tested by varying the parameters. The biosynthesized nanoparticles were characterized using the UV–Vis spectrophotometer to identify the surface plasmon resonance peaks corresponding to gold nanoparticles. The bio-moieties responsible for the synthesis of gold nanoparticles were identified using the Fourier Transform Infra-Red Spectroscopy. The crystalline nature was detected by using an X-Ray Diffractometer. Atomic Force Microscope viewed the 3D surface image of the gold nanoparticle. The shape and morphology of the nanoparticle were identified by using a Field Emission Scanning Electron Microscope. The active compounds for gold nanoparticle synthesis were identified using Gas Chromatography-Mass Spectrometry. The gold nanoparticle was synthesized in various colors and used for dyeing cotton fabrics. The dyed cotton materials were exposed to various stress conditions to determine the color fastening.


Vacuum ◽  
2020 ◽  
Vol 182 ◽  
pp. 109719 ◽  
Author(s):  
Eka Angasa ◽  
Yulia Eka Putri ◽  
Zulhadjri ◽  
Novesar Jamarun ◽  
Syukri Arief

2017 ◽  
Vol 1147 ◽  
pp. 1-6 ◽  
Author(s):  
O.J. Nava ◽  
C.A. Soto-Robles ◽  
C.M. Gómez-Gutiérrez ◽  
A.R. Vilchis-Nestor ◽  
A. Castro-Beltrán ◽  
...  

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Silaturahmi Silaturahmi ◽  
Zaidiyah Zaidiyah ◽  
Tengku Mia Rahmiati

The use of colorants in the dried noodle manufactures is an effort of product diversification. Besides of being used as a natural coloring agent, this peel extract is also used to improve nutritional value of the expected product. The purpose of this study was to determine the effect of red dragon fruit peel extract on the physical quality of dried noodle.  The study was conducted by using Completely Randomized Design (CRD) method with one factor, namely concentration of red dragon fruit peel extract (N1 = 10 ml, N2 = 15 ml, N3 = 20 ml, N4 = 25 ml, N5 = 30 ml).  The observations of its physical quality consisted of water absorption, solid loss during cooking, and organoleptic tests (aroma and color).  The best quality of dried noodle was obtained by using 30 ml red dragon fruit peel extract (N5) with physical properties, namely DSA levels of 351.92%, solid loss during cooking 4.78%, aroma 3.79 (like) and color 3.89 (like).


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