scholarly journals Lipid–polymer hybrid nanoparticles as a next-generation drug delivery platform: state of the art, emerging technologies, and perspectives

2019 ◽  
Vol Volume 14 ◽  
pp. 1937-1952 ◽  
Author(s):  
Anubhab Mukherjee ◽  
Ariana K Waters ◽  
Pranav Kalyan ◽  
Achal Singh Achrol ◽  
Santosh Kesari ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Emerging Technologies ◽  
State Of The Art ◽  
Hybrid Nanoparticles ◽  
Next Generation ◽  
Polymer Hybrid ◽  
Delivery Platform

scholarly journals Self-Assembled Lipid−Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform

ACS Nano ◽  
2008 ◽  
Vol 2 (8) ◽  
pp. 1696-1702 ◽  
Author(s):  
Liangfang Zhang ◽  
Juliana M. Chan ◽  
Frank X. Gu ◽  
June-Wha Rhee ◽  
Andrew Z. Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hybrid Nanoparticles ◽  
Polymer Hybrid ◽  
Delivery Platform ◽  
Self Assembled

Core–shell-type lipid–polymer hybrid nanoparticles as a drug delivery platform

2013 ◽  
Vol 9 (4) ◽  
pp. 474-491 ◽  
Author(s):  
Bivash Mandal ◽  
Himanshu Bhattacharjee ◽  
Nivesh Mittal ◽  
Hongkee Sah ◽  
Pavan Balabathula ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hybrid Nanoparticles ◽  
Core Shell ◽  
Polymer Hybrid ◽  
Shell Type ◽  
Delivery Platform

scholarly journals Extracellular vesicles as a next-generation drug delivery platform

2021 ◽  
Author(s):  
Inge Katrin Herrmann ◽  
Matthew John Andrew Wood ◽  
Gregor Fuhrmann
Keyword(s):  
Drug Delivery ◽  
Extracellular Vesicles ◽  
Next Generation ◽  
Delivery Platform

scholarly journals Lipid-polymer hybrid nanoparticles: Development & statistical optimization of norfloxacin for topical drug delivery system

2017 ◽  
Vol 2 (4) ◽  
pp. 269-280 ◽  
Author(s):  
Vivek Dave ◽  
Renu Bala Yadav ◽  
Kriti Kushwaha ◽  
Sachdev Yadav ◽  
Swapnil Sharma ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Statistical Optimization ◽  
Hybrid Nanoparticles ◽  
Topical Drug Delivery ◽  
Polymer Hybrid

Development and optimization of methotrexate-loaded lipid-polymer hybrid nanoparticles for controlled drug delivery applications

2017 ◽  
Vol 533 (1) ◽  
pp. 156-168 ◽  
Author(s):  
Nayab Tahir ◽  
Asadullah Madni ◽  
Vimalkumar Balasubramanian ◽  
Mubashar Rehman ◽  
Alexandra Correia ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Drug Delivery ◽  
Hybrid Nanoparticles ◽  
Polymer Hybrid ◽  
Drug Delivery Applications

Microfluidic Synthesis of Lipid-Polymer Hybrid Nanoparticles for Targeted Drug Delivery

MRS Advances ◽  
2016 ◽  
Vol 1 (29) ◽  
pp. 2155-2160
Author(s):  
Eri A. Takami ◽  
Folarin Erogbogbo
Keyword(s):  
Drug Delivery ◽  
Low Cost ◽  
Three Dimensional ◽  
Hybrid Nanoparticles ◽  
Dimensional Structure ◽  
Force Microscopy ◽  
Polymer Hybrid ◽  
Medical Issues ◽  
Transmission Electron ◽  
Size And Morphology

ABSTRACTLipid-polymer hybrid nanoparticles (LPHN) have great potential as drug delivery devices for treatment of serious medical issues such as cardiovascular disease, tuberculosis, and cancer. Nanoprecipitation is a commonly used method to synthesize LPHN in a low cost manner. However, this multi-step process proves to be difficult in consistently producing uniformly sized nanoparticles. Here we developed a microfluidic device that utilizes a three-channel pathway and mixer channel to synthesize uniformly sized LPHN in a controlled manner. Dynamic light scattering results of the microfluidic synthesized nanoparticles show decrease in diameter size from 140 nm to 40 nm as the Reynolds number of the channel inflow increases. Transmission electron microscopy confirms the size and morphology of the nanoparticles. Three dimensional structure of the LPHN were observed using atomic force microscopy. The production of higher quality nanoparticles using our microfluidics device can expedite the research and development process of drug delivering lipid polymer nanoparticles.

scholarly journals Nanoarchitectonics: Complexes and Conjugates of Platinum Drugs with Silicon Containing Nanocarriers. An Overview

2021 ◽  
Vol 22 (17) ◽  
pp. 9264
Author(s):  
Kinga Piorecka ◽  
Jan Kurjata ◽  
Wlodzimierz A. Stanczyk
Keyword(s):  
Drug Delivery ◽  
Driving Force ◽  
State Of The Art ◽  
Platinum Drugs ◽  
Research Groups ◽  
Current State ◽  
Delivery Platform ◽  
Silicon Based ◽  
Intensive Search

The development in the area of novel anticancer prodrugs (conjugates and complexes) has attracted growing attention from many research groups. The dangerous side effects of currently used anticancer drugs, including cisplatin and other platinum based drugs, as well their systemic toxicity is a driving force for intensive search and presents a safer way in delivery platform of active molecules. Silicon based nanocarriers play an important role in achieving the goal of synthesis of the more effective prodrugs. It is worth to underline that silicon based platform including silica and silsesquioxane nanocarriers offers higher stability, biocompatibility of such the materials and pro-longed release of active platinum drugs. Silicon nanomaterials themselves are well-known for improving drug delivery, being themselves non-toxic, and versatile, and tailored surface chemistry. This review summarizes the current state-of-the-art within constructs of silicon-containing nano-carriers conjugated and complexed with platinum based drugs. Contrary to a number of other reviews, it stresses the role of nano-chemistry as a primary tool in the development of novel prodrugs.

scholarly journals Lipid Polymer Hybrid Nanoparticles: A Novel Approach for Drug Delivery

2020 ◽  
Author(s):  
Nayab Tahir ◽  
Muhammad Tahir Haseeb ◽  
Asadullah Madni ◽  
Farzana Parveen ◽  
Muhammad Muzamil Khan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hybrid Nanoparticles ◽  
Polymer Hybrid ◽  
Novel Approach
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