scholarly journals A novel composite scaffold of Cu-doped nano calcium-deficient hydroxyapatite/multi-(amino acid) copolymer for bone tissue regeneration

2019 ◽  
Vol Volume 14 ◽  
pp. 3331-3343 ◽  
Author(s):  
Ping Mou ◽  
Haitao Peng ◽  
Li Zhou ◽  
Lin Li ◽  
Hong Li ◽  
...  
Keyword(s):  
Amino Acid ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Composite Scaffold ◽  
Bone Tissue Regeneration ◽  
Acid Copolymer

Fabrication andin vivoevaluation of an osteoblast-conditioned nano-hydroxyapatite/gelatin composite scaffold for bone tissue regeneration

2016 ◽  
Vol 104 (8) ◽  
pp. 2001-2010 ◽  
Author(s):  
Ali Samadikuchaksaraei ◽  
Mazaher Gholipourmalekabadi ◽  
Elham Erfani Ezadyar ◽  
Mahmoud Azami ◽  
Masoud Mozafari ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Composite Scaffold ◽  
Bone Tissue Regeneration

Preparation of an rhBMP-2 loaded mesoporous bioactive glass/calcium phosphate cement porous composite scaffold for rapid bone tissue regeneration

2015 ◽  
Vol 3 (43) ◽  
pp. 8558-8566 ◽  
Author(s):  
Nan Li ◽  
Chuan Jiang ◽  
Xingdi Zhang ◽  
Xinfeng Gu ◽  
Jingwei Zhang ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Bioactive Glass ◽  
Bone Tissue ◽  
Tissue Regeneration ◽  
Calcium Phosphate Cement ◽  
Composite Scaffold ◽  
Early Stage ◽  
Bone Tissue Regeneration ◽  
Porous Composite ◽  
Mesoporous Bioactive Glass

An rhBMP-2/MBG/CPC scaffold is beneficial for rapid bone tissue regeneration in the early stage.

Relevance of fiber integrated gelatin-nanohydroxyapatite composite scaffold for bone tissue regeneration

2015 ◽  
Vol 26 (40) ◽  
pp. 405101 ◽  
Author(s):  
Bibi Halima Shamaz ◽  
A Anitha ◽  
Manju Vijayamohan ◽  
Shruthy Kuttappan ◽  
Shantikumar Nair ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Composite Scaffold ◽  
Bone Tissue Regeneration

Novel calcified gum Arabic porous nano-composite scaffold for bone tissue regeneration

2017 ◽  
Vol 488 (4) ◽  
pp. 671-678 ◽  
Author(s):  
M. Hadavi ◽  
S. Hasannia ◽  
Sh. Faghihi ◽  
F. Mashayekhi ◽  
H.H. Zadeh ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Composite Scaffold ◽  
Gum Arabic ◽  
Bone Tissue Regeneration ◽  
Nano Composite

Nanostructured magnetic Mg2SiO4-CoFe2O4 composite scaffold with multiple capabilities for bone tissue regeneration

2019 ◽  
Vol 99 ◽  
pp. 83-95 ◽  
Author(s):  
Ashkan Bigham ◽  
Amir Hamed Aghajanian ◽  
Shima Behzadzadeh ◽  
Zahra Sokhani ◽  
Sara Shojaei ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Composite Scaffold ◽  
Bone Tissue Regeneration

scholarly journals The Construction of Multi-Incorporated Polylactic Composite Nanofibrous Scaffold for the Potential Applications in Bone Tissue Regeneration

Nanomaterials ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 2402
Author(s):  
Du Nie ◽  
Yi Luo ◽  
Guang Li ◽  
Junhong Jin ◽  
Shenglin Yang ◽  
...  
Keyword(s):  
Bone Tissue ◽  
Tissue Regeneration ◽  
Composite Scaffold ◽  
Nanofibrous Scaffold ◽  
Bone Tissue Regeneration ◽  
Calcium Deposition ◽  
Regeneration Ability ◽  
Bioactive Components ◽  
Bone Mesenchymal Stem Cells ◽  
Potential Applications

To improve the bone regeneration ability of pure polymer, varieties of bioactive components were incorporated to a biomolecular scaffold with different structures. In this study, polysilsesquioxane (POSS), pearl powder and dexamethasone loaded porous carbon nanofibers (DEX@PCNFs) were incorporated into polylactic (PLA) nanofibrous scaffold via electrospinning for the application of bone tissue regeneration. The morphology observation showed that the nanofibers were well formed through electrospinning process. The mineralization test of incubation in simulated body fluid (SBF) revealed that POSS incorporated scaffold obtained faster hydroxyapatite depositing ability than pristine PLA nanofibers. Importantly, benefitting from the bioactive components of pearl powder like bone morphogenetic protein (BMP), bone mesenchymal stem cells (BMSCs) cultured on the composite scaffold presented higher proliferation rate. In addition, by further incorporating with DEX@PCNFs, the alkaline phosphatase (ALP) level and calcium deposition were a little higher based on pearl powder. Consequently, the novel POSS, pearl powder and DEX@PCNFs multi-incorporated PLA nanofibrous scaffold can provide better ability to enhance the biocompatibility and accelerate osteogenic differentiation of BMSCs, which has potential applications in bone tissue regeneration.

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