scholarly journals Mesoporous composite nanoparticles for dual-modality ultrasound/magnetic resonance imaging and synergistic chemo-/thermotherapy against deep tumors

2017 ◽  
Vol Volume 12 ◽  
pp. 7273-7289 ◽  
Author(s):  
Nan Zhang ◽  
Ronghui Wang ◽  
Junnian Hao ◽  
Yang Yang ◽  
Hongmi Zou ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Composite Nanoparticles ◽  
Resonance Imaging ◽  
Mesoporous Composite ◽  
Dual Modality

Preparation of Gd-Au Dendrimer-Entrapped Gold Nanoparticles-Folic Acid Nanoparticles and Its Application in Computed Tomography/Magnetic Resonance Imaging Dual-Modality Diagnosis of Abdominal Tumors

2021 ◽  
Vol 13 (7) ◽  
pp. 1364-1373
Author(s):  
Yumei Zhang ◽  
Ruina Pei ◽  
Tao Luo
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Gold Nanoparticles ◽  
Folic Acid ◽  
Magnetic Resonance ◽  
Receptor Expression ◽  
Average Particle ◽  
Resonance Imaging ◽  
Dual Modality ◽  
Abdominal Tumors

ABSTRACTThe development of nanomaterials, especially the development of multi-modality imaging nanoprobe technology has become a reality for tumor imaging diagnosis. In this study, the gadolinium ion chelating agent (2,2′,2′′-(10-(2-(2, 5-dioxopyrrolidin-1-oxyl)-2 oxoethyl)-1, 4, 7, 10-tetraazacyclododecane-1, 4, 7-tri)triacetic acid) (DOTA-NHS) and polyethylene glycol (PEG)-modified targeting ligand PEG-folic acid (FA) were grafted onto the PEG-modified fifth-generation polyamide-amine dendrimer (P5-NH2), which were undertaken as standards to wrap gold nanoparticles. Then, remaining amino group was acetylated to acquire Gd–Au DENPS-FA nanoparticles. Biocompatibility and cytotoxicity of nanoparticles were analyzed while characterizing them. The cases with unidentified tumors (mass diameter >4.5 cm) of abdominal or pelvic origin were selected and used for clinical study of computed tomography (CT)/magnetic resonance imaging (MRI) dual-modality abdominal tumors. In the test, average particle size of Gd-Au DENPs-FA nanoparticles was 4.2 nm, and they had good water solubility and stability in aqueous solution. When concentration of Au+ nanoparticles increased, the cell morphology remained normal, only a small number of round cells appeared, and the cell activity remained above 80%. GD-Au DENPs-FA nanoparticles had a good targeting specificity for KB cells with high folate receptor expression. During 6–24 hours of injection, the signal at the tumor site of the patient was enhanced markedly, namely the targeted gold nanoparticles were bound to the tumor tissue and the metabolic rate was slow. Based on this material, CT/MRI imaging could be performed in the patient’s body and further used for the early diagnosis of abdominal tumors.

scholarly journals Dual-modality photothermal optical coherence tomography and magnetic-resonance imaging of carbon nanotubes

2012 ◽  
Vol 37 (5) ◽  
pp. 872 ◽  
Author(s):  
Jason M. Tucker-Schwartz ◽  
Tu Hong ◽  
Daniel C. Colvin ◽  
Yaqiong Xu ◽  
Melissa C. Skala
Keyword(s):  
Magnetic Resonance Imaging ◽  
Carbon Nanotubes ◽  
Optical Coherence Tomography ◽  
Magnetic Resonance ◽  
Optical Coherence ◽  
Resonance Imaging ◽  
Dual Modality

Morphology and Crsytallization Control of Multifunctional GdPO4:Eu Nanostructures by Hydrothermal Preparation

2014 ◽  
Vol 1082 ◽  
pp. 14-17 ◽  
Author(s):  
Bi Lin Shao ◽  
Xian Zhu Xu ◽  
Min Liao ◽  
Yan Li Wu
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Hydrothermal Method ◽  
Ph Value ◽  
Precursor Solution ◽  
Hydrothermal Time ◽  
Resonance Imaging ◽  
Hydrothermal Preparation ◽  
Dual Modality

Here, GdPO4:Eu3+ nanostructures with different morphology and size were successfully synthesized by a hydrothermal method and characterized by SEM ,XRD, PL and VSM . The results indicated that the morphology and crystallization strongly depended on the pH value of precursor solution as well as the surfactant and hydrothermal time. The photoluminescent and paramagnetic results showed the nanorods could be used as a promising nanoprobe for dual-modality with optical bioimaging and magnetic resonance imaging.

Sequential Growth of NaYF4:Yb/Er@NaGdF4 Nanodumbbells for Dual-Modality Fluorescence and Magnetic Resonance Imaging

2017 ◽  
Vol 9 (11) ◽  
pp. 9226-9232 ◽  
Author(s):  
Hui-Qin Wen ◽  
Huang-Yong Peng ◽  
Kun Liu ◽  
Mao-Hong Bian ◽  
Yun-Jun Xu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Dual Modality

Use of a Simple, Inexpensive Dual-Modality Phantom as a Learning Tool for Magnetic Resonance Imaging-Ultrasound Fusion Techniques

2018 ◽  
Vol 37 (8) ◽  
pp. 2083-2089 ◽  
Author(s):  
William R. Walter ◽  
Christopher J. Burke ◽  
Mamadou Diallo ◽  
Ronald S. Adler
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Learning Tool ◽  
Dual Modality
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