scholarly journals Targeting T1 and T2 dual modality enhanced magnetic resonance imaging of tumor vascular endothelial cells based on peptides-conjugated manganese ferrite nanomicelles

2016 ◽  
Vol Volume 11 ◽  
pp. 4051-4063 ◽  
Author(s):  
Mingfu Gong ◽  
Hua Yang ◽  
Song Zhang ◽  
Yan Yang ◽  
Dong Zhang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Endothelial Cells ◽  
Magnetic Resonance ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial ◽  
Manganese Ferrite ◽  
Resonance Imaging ◽  
Dual Modality

Organised haematoma of the maxillary sinus: pathophysiological differences suggesting a new aetiological hypothesis

2013 ◽  
Vol 127 (5) ◽  
pp. 519-524 ◽  
Author(s):  
S Urata ◽  
M Ohki ◽  
T Tsutsumi ◽  
S Kikuchi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Endothelial Cells ◽  
Maxillary Sinus ◽  
Vascular Endothelial Cells ◽  
Histopathological Examination ◽  
The Other ◽  
Vascular Endothelial ◽  
Blood Components ◽  
Resonance Imaging ◽  
Basal Portion

AbstractBackground and objectives:Organised haematomas of the maxillary sinus are rare, non-neoplastic, haemorrhagic lesions which can extend into the nasal cavity and/or the other paranasal sinuses. This study aimed to investigate the pathology of maxillary sinus organised haematoma, and also proposes a new aetiological hypothesis based on the observed pathology.Methods:Biopsies, computed tomography, magnetic resonance imaging and post-surgical histopathological examination of resected specimens were carried out.Conclusion:Distinct pathological differences were observed between the basal and peripheral portions of organised haematomas. We propose that an organised haematoma originates from the exudation of blood components between vascular endothelial cells. As a result, the basal portion consists of aggregated, dilated vessels around the natural ostium of the maxillary sinus. In addition, pseudovessels, without endothelial cells, arise from endocapillary vessels within the haematoma. Exudation of additional blood components from the pseudovessels advances the growth of the organised haematoma.

scholarly journals Manganese Ferrite Nanoparticles Encapsulated into Vitamin E/Sphingomyelin Nanoemulsions as Contrast Agents for High‐Sensitive Magnetic Resonance Imaging

2021 ◽  
pp. 2101019
Author(s):  
Sandra Díez‐Villares ◽  
Miguel A. Ramos‐Docampo ◽  
Andrés da Silva‐Candal ◽  
Pablo Hervella ◽  
Abi J. Vázquez‐Ríos ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Vitamin E ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Ferrite Nanoparticles ◽  
Manganese Ferrite ◽  
Resonance Imaging

Preparation of Gd-Au Dendrimer-Entrapped Gold Nanoparticles-Folic Acid Nanoparticles and Its Application in Computed Tomography/Magnetic Resonance Imaging Dual-Modality Diagnosis of Abdominal Tumors

2021 ◽  
Vol 13 (7) ◽  
pp. 1364-1373
Author(s):  
Yumei Zhang ◽  
Ruina Pei ◽  
Tao Luo
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Gold Nanoparticles ◽  
Folic Acid ◽  
Magnetic Resonance ◽  
Receptor Expression ◽  
Average Particle ◽  
Resonance Imaging ◽  
Dual Modality ◽  
Abdominal Tumors

ABSTRACTThe development of nanomaterials, especially the development of multi-modality imaging nanoprobe technology has become a reality for tumor imaging diagnosis. In this study, the gadolinium ion chelating agent (2,2′,2′′-(10-(2-(2, 5-dioxopyrrolidin-1-oxyl)-2 oxoethyl)-1, 4, 7, 10-tetraazacyclododecane-1, 4, 7-tri)triacetic acid) (DOTA-NHS) and polyethylene glycol (PEG)-modified targeting ligand PEG-folic acid (FA) were grafted onto the PEG-modified fifth-generation polyamide-amine dendrimer (P5-NH2), which were undertaken as standards to wrap gold nanoparticles. Then, remaining amino group was acetylated to acquire Gd–Au DENPS-FA nanoparticles. Biocompatibility and cytotoxicity of nanoparticles were analyzed while characterizing them. The cases with unidentified tumors (mass diameter >4.5 cm) of abdominal or pelvic origin were selected and used for clinical study of computed tomography (CT)/magnetic resonance imaging (MRI) dual-modality abdominal tumors. In the test, average particle size of Gd-Au DENPs-FA nanoparticles was 4.2 nm, and they had good water solubility and stability in aqueous solution. When concentration of Au+ nanoparticles increased, the cell morphology remained normal, only a small number of round cells appeared, and the cell activity remained above 80%. GD-Au DENPs-FA nanoparticles had a good targeting specificity for KB cells with high folate receptor expression. During 6–24 hours of injection, the signal at the tumor site of the patient was enhanced markedly, namely the targeted gold nanoparticles were bound to the tumor tissue and the metabolic rate was slow. Based on this material, CT/MRI imaging could be performed in the patient’s body and further used for the early diagnosis of abdominal tumors.

Magnetic Resonance Imaging of Endothelial Cells with Vectorized Iron Oxide Nanoparticles

2011 ◽  
Vol 151 (6) ◽  
pp. 726-730 ◽  
Author(s):  
M. A. Abakumov ◽  
A. E. Goldt ◽  
M. Sokolsky-Papkov ◽  
Y. A. Zorkina ◽  
V. P. Baklaushev ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Endothelial Cells ◽  
Iron Oxide ◽  
Magnetic Resonance ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Resonance Imaging

scholarly journals Dual-modality photothermal optical coherence tomography and magnetic-resonance imaging of carbon nanotubes

2012 ◽  
Vol 37 (5) ◽  
pp. 872 ◽  
Author(s):  
Jason M. Tucker-Schwartz ◽  
Tu Hong ◽  
Daniel C. Colvin ◽  
Yaqiong Xu ◽  
Melissa C. Skala
Keyword(s):  
Magnetic Resonance Imaging ◽  
Carbon Nanotubes ◽  
Optical Coherence Tomography ◽  
Magnetic Resonance ◽  
Optical Coherence ◽  
Resonance Imaging ◽  
Dual Modality

Morphology and Crsytallization Control of Multifunctional GdPO4:Eu Nanostructures by Hydrothermal Preparation

2014 ◽  
Vol 1082 ◽  
pp. 14-17 ◽  
Author(s):  
Bi Lin Shao ◽  
Xian Zhu Xu ◽  
Min Liao ◽  
Yan Li Wu
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Hydrothermal Method ◽  
Ph Value ◽  
Precursor Solution ◽  
Hydrothermal Time ◽  
Resonance Imaging ◽  
Hydrothermal Preparation ◽  
Dual Modality

Here, GdPO4:Eu3+ nanostructures with different morphology and size were successfully synthesized by a hydrothermal method and characterized by SEM ,XRD, PL and VSM . The results indicated that the morphology and crystallization strongly depended on the pH value of precursor solution as well as the surfactant and hydrothermal time. The photoluminescent and paramagnetic results showed the nanorods could be used as a promising nanoprobe for dual-modality with optical bioimaging and magnetic resonance imaging.

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