scholarly journals Lung-targeting drug delivery system of baicalin-loaded nanoliposomes: development, biodistribution in rabbits, and pharmacodynamics in nude mice bearing orthotopic human lung cancer

2016 ◽  
Vol Volume 12 ◽  
pp. 251-261 ◽  
Author(s):  
Yumeng Wei ◽  
Jing Liang ◽  
Xiaoli Zheng ◽  
Chao Pi ◽  
Hao Liu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Nude Mice ◽  
Human Lung ◽  
Human Lung Cancer ◽  
Lung Targeting

Quantitative analysis of distribution and fate of human lung cancer emboli labeled with 125I-5-iodo-2?-deoxyuridine in nude mice

Surgery Today ◽  
1993 ◽  
Vol 23 (11) ◽  
pp. 979-983 ◽  
Author(s):  
Kazuhiko Yoshida ◽  
Touru Fujikawa ◽  
Akihiro Tanabe ◽  
Kenji Sakurai
Keyword(s):  
Lung Cancer ◽  
Quantitative Analysis ◽  
Nude Mice ◽  
Human Lung ◽  
Human Lung Cancer

Treatment of human lung cancer-bearing nude mice with90Y-LC-l

2000 ◽  
Vol 12 (2) ◽  
pp. 155-156
Author(s):  
Si-jun Lin ◽  
Liang Zeng ◽  
Gao-ren Zhong ◽  
Zi-rui Ge
Keyword(s):  
Lung Cancer ◽  
Nude Mice ◽  
Human Lung ◽  
Human Lung Cancer

scholarly journals Biopolymer Hydrogel Scaffolds Containing Doxorubicin as A Localized Drug Delivery System for Inhibiting Lung Cancer Cell Proliferation

Polymers ◽  
2021 ◽  
Vol 13 (20) ◽  
pp. 3580
Author(s):  
Chuda Chittasupho ◽  
Jakrapong Angklomklew ◽  
Thanu Thongnopkoon ◽  
Wongwit Senavongse ◽  
Pensak Jantrawut ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Carboxymethyl Cellulose ◽  
Encapsulation Efficiency ◽  
Lung Cancer Cell ◽  
Hydrogel Scaffold ◽  
Hydrogel Scaffolds ◽  
Localized Drug Delivery

A hydrogel scaffold is a localized drug delivery system that can maintain the therapeutic level of drug concentration at the tumor site. In this study, the biopolymer hydrogel scaffold encapsulating doxorubicin was fabricated from gelatin, sodium carboxymethyl cellulose, and gelatin/sodium carboxymethyl cellulose mixture using a lyophilization technique. The effects of a crosslinker on scaffold morphology and pore size were determined using scanning electron microscopy. The encapsulation efficiency and the release profile of doxorubicin from the hydrogel scaffolds were determined using UV-Vis spectrophotometry. The anti-proliferative effect of the scaffolds against the lung cancer cell line was investigated using an MTT assay. The results showed that scaffolds made from different types of natural polymer had different pore configurations and pore sizes. All scaffolds had high encapsulation efficiency and drug-controlled release profiles. The viability and proliferation of A549 cells, treated with gelatin, gelatin/SCMC, and SCMC scaffolds containing doxorubicin significantly decreased compared with control. These hydrogel scaffolds might provide a promising approach for developing a superior localized drug delivery system to kill lung cancer cells.

Human Lung Cancer Xenografts and Metastases in Athymic (Nude) Mice

2015 ◽  
pp. 277-280
Author(s):  
Adi F. Gazdar ◽  
Robert Shoemaker ◽  
Joseph Mayo ◽  
Herbert K. Oie ◽  
Patricia Donovan ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Nude Mice ◽  
Human Lung ◽  
Human Lung Cancer ◽  
Athymic Nude Mice
Sign in / Sign up

Export Citation Format

Share Document