scholarly journals Colonization Rate of Potential Neonatal Disease-Causing Bacteria, Associated Factors, and Antimicrobial Susceptibility Profile Among Pregnant Women Attending Government Hospitals in Hawassa, Ethiopia

2021 ◽  
Vol Volume 14 ◽  
pp. 3159-3168
Author(s):  
Samrawit Birhane Fiseha ◽  
Getamesay Mulatu Jara ◽  
Elshaday Azerefegn Woldetsadik ◽  
Fanuel Belayneh Bekele ◽  
Musa Mohammed Ali
2018 ◽  
Vol 39 (1) ◽  
pp. 77
Author(s):  
Ana Elisa Belotto Morguette ◽  
Renata Perugini Biasi-Garbin ◽  
Eliane Saori Otaguiri ◽  
Marcia Regina Eches Perugini ◽  
Marsileni Pelisson ◽  
...  

Um estudo retrospectivo foi realizado com gestantes atendidas no Hospital Universitário de Londrina, Paraná, Brasil para determinar a prevalência de colonização vaginal-retal por Estreptococos do Grupo B (EGB) e o perfil de sensibilidade de EGB aos antimicrobianos utilizados para a antibioticoterapia profilática intraparto. Swabs vaginais-retais foram coletados de 2.901 mulheres entre a 35ª e 37ª semana de gestação. Destes, 528 (18,2%) apresentaram cultura positiva para EGB, e 0,4%, 10,2% e 10% dos isolados foram resistentes à penicilina, eritromicina e clindamicina, respectivamente. Estes resultados destacam a importância de vigilância contínua da colonização por EGB em gestantes para a prevenção de infecções em neonatos por EGB.


2011 ◽  
Vol 43 (9) ◽  
pp. 742-746 ◽  
Author(s):  
Esau C. Joao ◽  
Maria Isabel Gouvêa ◽  
Jacqueline A. Menezes ◽  
Haroldo J. Matos ◽  
Maria Letícia S. Cruz ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Mekuria Edae ◽  
Zelalem Teklemariam ◽  
Fitsum Weldegebreal ◽  
Degu Abate

Background. Asymptomatic bacteriuria is one of the major risk factors for the development of urinary tract infections during pregnancy which accounts for about 70% of the cases. However, there is no guideline which recommends routine screening of pregnant women for asymptomatic bacteriuria in most of developing countries including Ethiopia. Thus, the aim of this study was to determine the magnitude, associated factors, and antimicrobial susceptibility pattern of asymptomatic bacteriuria among pregnant women. Methods. A cross-sectional study was conducted from March to April 2019. Data were collected through face-to-face interview and analyzed using Statistical Package for Social Science version 22. A test of association was performed using logistic regression and P value less than 0.05 was considered statistically significant. Results. The overall prevalence of asymptomatic bacteriuria was 19.9%. Direction of wiping after genital wash, postcoital urination, and catheterization were factors significantly associated with asymptomatic bacteriuria. Most of the isolated Gram positive were highly sensitive to Ceftriaxone (90.9%). Coagulase-negative staphylococci showed higher sensitivity to Augmentin (75.0) and Ceftriaxone (87.5%), whereas they showed resistance to Clindamycin (68.7%) and Ampicillin (62.5%). Gram-negative bacteria isolates showed higher sensitivity to Ceftriaxone (88.2%), Gentamycin (67.5%), and Augmentin (64.7%), while they showed resistance to Ampicillin (70.5%) and Clindamycin (50.0%). Conclusion. The overall prevalence of asymptomatic bacteriuria among pregnant women in this study was high. Direction of wiping after genital wash, catheterization, and postcoital urination increases the odds of asymptomatic bacteriuria. Therefore, health education on the predisposing factors is strongly recommended.


2020 ◽  
Vol 29 (3) ◽  
pp. 87-96
Author(s):  
Amal F. Makled ◽  
Ahmed B. Mahmoud ◽  
Said A. Saleh ◽  
Sara G. Hegazy ◽  
Rasha G. Mostafa

Background: Although, GBS is a natural flora of the ano-rectal region, it may colonize vagina and many infants can be infected during the passage through the birth canal. It has emerged as a leading cause of neonatal infections and deaths. Objectives: To estimate the rate of recto-vaginal carriage of GBS among pregnant females, describe its antimicrobial susceptibility profile and to detect some of its virulence genes by multiplex PCR. Methodology: Vaginal, anorectal and neonatal throat swabs which were collected from two-hundred and fifty pregnant women were inoculated in Todd-Hewitt broth for 24 hours then inoculated on blood agar plates. Antimicrobial susceptibility testing for GBS isolates was done and its virulence genes (scpB, bca, rib and HvgA) were identified by PCR. Also, the relation between these virulence genes and antimicrobial susceptibility was studied. Results: Among 250 pregnant females, 36(14.4%) were identified as GBS carriers with exclusive vaginal and anorectal colonization rates of 4% and 10.4% respectively. All isolates were susceptible to penicillin, ampicillin, cefepime, cefotaxime, ceftriaxone, vancomycin and linezolid. On the other hand, 19.4%, 80.6%, 44.4% and 13.9% of GBS isolates were resistant to each of erythromycin and azithromycin, tetracycline, levofloxacin and clindamycin respectively. ScpB, rib, and Hvg-A genes were identified in 100%, 69.4% and 33.3% of GBS isolates respectively. None of them had the bca gene. Conclusion: Screening for GBS colonization of pregnant females is recommended and determination of virulence and different surface proteins would be relevant for better diagnosis and further possible formulation of a vaccine


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