scholarly journals Management of Chlamydia trachomatis genital tract infection: screening and treatment challenges

2011 ◽  
pp. 19 ◽  
Author(s):  
Brandie Depaoli Taylor ◽  
Haggerty
Keyword(s):  
Chlamydia Trachomatis ◽  
Tract Infection ◽  
Genital Tract ◽  
Genital Tract Infection

A novel guinea pig model of Chlamydia trachomatis genital tract infection

Vaccine ◽  
2011 ◽  
Vol 29 (35) ◽  
pp. 5994-6001 ◽  
Author(s):  
Marien I. de Jonge ◽  
Sander A.S. Keizer ◽  
Hicham M. el Moussaoui ◽  
Lieke van Dorsten ◽  
Rima Azzawi ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Tract Infection ◽  
Guinea Pig ◽  
Genital Tract ◽  
Pig Model ◽  
Genital Tract Infection ◽  
Guinea Pig Model

scholarly journals Prior Genital Tract Infection with a Murine or Human Biovar of Chlamydia trachomatis Protects Mice against Heterotypic Challenge Infection

1999 ◽  
Vol 67 (6) ◽  
pp. 3019-3025 ◽  
Author(s):  
Kyle H. Ramsey ◽  
Todd W. Cotter ◽  
Rena D. Salyer ◽  
Gurwattan S. Miranpuri ◽  
Michael A. Yanez ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Tract Infection ◽  
Genital Tract ◽  
Primary Infection ◽  
Secondary Infection ◽  
Delayed Type Hypersensitivity ◽  
Genital Infection ◽  
Blast Transformation ◽  
Genital Tract Infection ◽  
Igg Antibody

ABSTRACT We sought to assess the degree of cross-protective immunity in a mouse model of chlamydial genital tract infection. Following resolution of genital infection with the mouse pneumonitis (MoPn) biovar ofChlamydia trachomatis, mice were challenged intravaginally with either MoPn or human serovar E or L2. The majority of animals previously infected with MoPn were solidly immune to challenge with either of the two human biovars. Surprisingly, approximately 50% of animals became reinfected when homologously challenged with MoPn, although the secondary infection yielded significantly lower numbers of the organism isolated over a shorter duration than in the primary infection. Primary infection with serovar E also protected against challenge with MoPn or serovar L2, although the degree of immune protection was lower than that resulting from primary infection with MoPn. Blast transformation and assessment of delayed-type hypersensitivity indicated that mice previously infected with either human or murine biovars produced broadly cross-reactive T cells that recognized epitopes of either murine or human biovars of C. trachomatis. Immunoblotting demonstrated that primary MoPn infection produced immunoglobulin G (IgG) antibody to antigens of MoPn as well as at least three distinct antigenic components of human serovar E, one of which was identical in molecular weight to the major outer membrane protein (MOMP). Primary infection with serovar E produced IgG antibody reactive against serovar E but not MoPn MOMP and against at least one ca. 60-kDa protein of both chlamydial strains. Our results indicate that primary genital infection of mice with murineC. trachomatis induces immunity against challenge with either of two human biovars.

scholarly journals Vaginal swabs are appropriate specimens for the diagnosis of genital tract infection with Chlamydia trachomatis

2008 ◽  
Vol 23 (2) ◽  
Author(s):  
Giacomo Audisio ◽  
Aldo Bossano ◽  
Denis Cauchi Inglott ◽  
Giovanni Orso Giacone ◽  
Maria Agnese Latino ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Tract Infection ◽  
Genital Tract ◽  
Genital Tract Infection ◽  
Vaginal Swabs

Lower genital tract infection with Chlamydia trachomatis and Neisseria gonorrhoeae in Icelandic women with salpingitis

1986 ◽  
Vol 155 (3) ◽  
pp. 602-607 ◽  
Author(s):  
Sigurdur S. Magnússon ◽  
Thordur Oskarsson ◽  
Reynir T. Geirsson ◽  
Benedikt Sveinsson ◽  
Olafur Steingrimsson ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Tract Infection ◽  
Neisseria Gonorrhoeae ◽  
Genital Tract ◽  
Genital Tract Infection ◽  
Lower Genital Tract ◽  
Lower Genital Tract Infection

scholarly journals Vaginal Swabs Are Appropriate Specimens for Diagnosis of Genital Tract Infection with Chlamydia trachomatis

2003 ◽  
Vol 41 (8) ◽  
pp. 3784-3789 ◽  
Author(s):  
J. Schachter ◽  
W. M. McCormack ◽  
M. A. Chernesky ◽  
D. H. Martin ◽  
B. Van Der Pol ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Tract Infection ◽  
Genital Tract ◽  
Genital Tract Infection ◽  
Vaginal Swabs
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