scholarly journals Enhanced Expression of miR-34c in Peripheral Plasma Associated with Diabetic Foot Ulcer in Type 2 Diabetes Patients

2021 ◽  
Vol Volume 14 ◽  
pp. 4263-4273
Author(s):  
Tingting Wu ◽  
Dandan Xie ◽  
Xiaotong Zhao ◽  
Murong Xu ◽  
Li Luo ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Peripheral Plasma ◽  
Enhanced Expression ◽  
Diabetes Patients

Fewer Type A personality traits in type 2 diabetes patients with diabetic foot ulcer

2021 ◽  
pp. 101245
Author(s):  
Bruno Vergès ◽  
Roxane Brands ◽  
Coralie Fourmont ◽  
Jean-Michel Petit ◽  
Isabelle Simoneau ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Personality Traits ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Type A ◽  
Type A Personality ◽  
Diabetes Patients

scholarly journals Modified tibial transverse transport technique for the treatment of ischemic diabetic foot ulcer in patients with type 2 diabetes

2021 ◽  
Vol 29 ◽  
pp. 100-105
Author(s):  
Yusong Yuan ◽  
Xiaofang Ding ◽  
Zhengwei Jing ◽  
Hao Lu ◽  
Kun Yang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Transport Technique

scholarly journals Role of toll like receptor-9 (1237 T/C) gene polymorphism in patients with type 2 diabetes and diabetic foot ulcer

2021 ◽  
Vol 1879 (2) ◽  
pp. 022012
Author(s):  
Furqan Naeem Al-Karawi ◽  
Naji Al-Hasnawiand Abeer Thaher ◽  
Thekra Abd Jebur Al-Kashwan
Keyword(s):  
Type 2 Diabetes ◽  
Gene Polymorphism ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Toll Like Receptor

scholarly journals Diabetic foot ulcer severity predicts mortality among veterans with type 2 diabetes

2017 ◽  
Vol 31 (3) ◽  
pp. 556-561 ◽  
Author(s):  
Meghan B. Brennan ◽  
Timothy M. Hess ◽  
Brian Bartle ◽  
Jennifer M. Cooper ◽  
Jonathan Kang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer

scholarly journals Decreased Plasma Maresin 1 Concentration Is Associated with Diabetic Foot Ulcer

2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Tian Miao ◽  
Bangliang Huang ◽  
Niexia He ◽  
Lihua Sun ◽  
Guangsheng Du ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Insulin Secretion ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Model Assessment ◽  
Homeostasis Model Assessment

Aims. To assess the maresin 1 (MaR1) contents in type 2 diabetic patients with or without diabetic foot ulcer and to analyze the association of MaR1 concentrations with several metabolism-related parameters. Methods. Plasma MaR1 concentrations were analyzed in 96 subjects with normal glucose tolerant (NC, n=43), type 2 diabetes (T2DM, n=40), or diabetic foot ulcer (DFU, n=13). The intravenous glucose tolerance test (IVGTT) and biochemical parameters were measured in all participants. Results. Plasma MaR1 concentrations were significant decreased in type 2 diabetes patient with or without DFU compared with NC (both P<0.001) and were lowest in DFU patients among these 3 groups. (DFU vs. T2DM, P<0.05). Plasma MaR1 concentrations were negatively correlated with BMI, waist circumference (Wc), waist hip ratio (WHR), systolic blood pressure (SBP), diastolic blood pressure (DBP), LDL-c, FPG, 2hPG, HbA1c, and homeostasis model assessment for insulin resistance (HOMA-IR) (all P<0.05) and were positively correlated with HDL-c, acute insulin response (AIR), area under the curve of the first-phase (0-10 min) insulin secretion (AUC), and homeostasis model assessment for beta-cell function (HOMA-β) (all P<0.05). After adjusting for age and sex, Wc, WHR, TG, FPG, 2hPG, HbA1c, HOMA-IR, AIR, AUC, and HOMA-β remain statistically significant (all P<0.05). Conclusions. Plasma MaR1 concentration were decreased in T2DM with or without DFUs and were the lowest in DFU patients. The decreased plasma MaR1 strongly associated with obesity, impaired glucose and lipid metabolism, reduced first-phase of glucose-stimulated insulin secretion, and enhanced insulin resistance.

scholarly journals Antioxidant and oxidative stress status in type 2 diabetes and diabetic foot ulcer

2008 ◽  
Vol 13 (2) ◽  
pp. 58-63 ◽  
Author(s):  
Kensese Sontin Mossanda ◽  
Elizabeth Bosede Bolajoko ◽  
Mpho Moropane ◽  
Francis Adeniyi ◽  
Olubayo Akinosun ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Type 2 Diabetes ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Oxidative Stress Status ◽  
And Oxidative Stress

scholarly journals Comparison Pai-1 Level in Type 2 Diabetes Mellitus with and Without Diabetic Foot Ulcer

2018 ◽  
Vol 1 (1) ◽  
pp. 1-5
Author(s):  
Alfi Dewi Sholat ◽  
Dairion Gatot ◽  
Savina Handayani ◽  
Andri Iskandar Mardia ◽  
Santi Syafril
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Diabetic Patients ◽  
Significant Difference ◽  
Pai 1

In type 2 diabetes mellitus, there are changes in hemostasis components, including overexpression of PAI-1. By these facts, the authors are interested in conducting the study of PAI-1 level in diabetic patients with and without foot ulcer. Methods: The sample of this research was collected cross-sectionally on 20 type 2 diabetic patients with foot ulcer and 20 without foot ulcer. Blood samples were taken to measure serum PAI-1 level, complete blood count and hemostasis screening test. Results: Statistical analysis showed there are significant differences in hemoglobin, trombosit, Fibrinogen and D-dimer levels in the ulcer and non-ulcer groups but no significant difference in PAI-1 level. Conclusions: No higher PAI – 1 level were found in diabetic foot ulcer group than those without diabetic foot ulcer. There was no significant difference between PAI-1 level and grade of diabetic foot ulcer.

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