scholarly journals Long Sleep Duration is Associated with Increased High-Sensitivity C-Reactive Protein: A Nationwide Study on Chinese Population

2020 ◽  
Vol Volume 13 ◽  
pp. 4423-4434
Author(s):  
Liyun He ◽  
Na Yang ◽  
Fan Ping ◽  
Lingling Xu ◽  
Wei Li ◽  
...  
2015 ◽  
Vol 32 ◽  
pp. 177-182 ◽  
Author(s):  
Maria K. Luojus ◽  
Soili M. Lehto ◽  
Tommi Tolmunen ◽  
Antti-Pekka Elomaa ◽  
Jussi Kauhanen

SLEEP ◽  
2020 ◽  
Vol 43 (8) ◽  
Author(s):  
Kyu-Man Han ◽  
Heon-Jeong Lee ◽  
Leen Kim ◽  
Ho-Kyoung Yoon

Abstract Study Objectives To investigate the association between weekend catch-up sleep (WCS) and the levels of high-sensitivity C-reactive protein (hsCRP)—a serum inflammatory maker—in adults Methods Data of 5,506 adults aged 19 years or older were obtained from the nationwide cross-sectional Korea National Health and Nutrition Examination Surveys conducted in 2016. Serum hsCRP level, weekday and weekend sleep durations, and sociodemographic and health-related characteristics were assessed. Participants whose weekend sleep duration was more than 1 h longer than their weekday sleep duration were included in the WCS group. hsCRP level was categorized into quartiles (i.e. highest, middle-high, middle-low, and lowest). Obesity was defined by body mass index ≥ 25.0 kg/m2. Results The WCS group included 1,901 participants (34.5%). In the logistic regression analysis controlling for all variables, adults in the WCS group were significantly less likely to show the highest hsCRP level (versus the lowest level) compared with those without WCS in the complete sample (adjusted odds ratio = 0.795, 95% confidence interval [CI] = 0.662 to 0.955). In a subgroup analysis, this association was significant only for those with weekday sleep duration of 6 h or lower. Longer WCS (≥3 h) was not associated with hsCRP levels. Non-obese people with WCS demonstrated a lower risk for high hsCRP levels, while there was no significant difference in obese people with WCS. Conclusions Our findings indicate that WCS may be beneficial for low-grade systemic inflammation in adults, particularly among those with shorter weekday sleep durations. WCS may also interact with obesity.


2009 ◽  
Vol 4 (4) ◽  
pp. 309-313 ◽  
Author(s):  
Enrico Vizzardi ◽  
Savina Nodari ◽  
Gregoriana Zanini ◽  
Alessandra Manerba ◽  
Silvia Frattini ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Hui-Xu Dai ◽  
Zhi-Ying Zhao ◽  
Yang Xia ◽  
Qi-Jun Wu ◽  
Yu-Hong Zhao

Purpose. The aim of the present cohort study was to explore the longitudinal association between high-sensitivity C-reactive protein (CRP) and hyperuricemia in Chinese population. Furthermore, we conducted subgroup analyses to explore this association according to age, sex, and body mass index. Methods. A total of 5,419 healthy participants were enrolled in the final cohort analysis. The high-sensitivity CRP level was measured by immunoturbidimetric assay. Hyperuricemia was defined as serum uric acid ≥7.0 mg/dL (416 μmol/L) in men and ≥6.0 mg/dL (357 μmol/L) in women. Multivariate logistic regression was used to analyze the association. Results. During the 4 years follow-up, 474 participants developed hyperuricemia. Compared with participants in the lowest tertile of high-sensitivity CRP, the multivariate-adjusted odds ratio (OR) (95% confidence interval [CI]) for incident hyperuricemia in the highest tertile was 1.36 (1.02, 1.82). In the subgroup analyses, high-sensitivity CRP was positively associated with the incidence of hyperuricemia after multivariate adjustments (P for trend=0.04) in women. Compared with the women in the lowest tertile of high-sensitivity CRP, the multivariate-adjusted OR (95% CI) in the highest tertile was 1.69 (1.10, 2.66). No statistically significant association was found in other subgroups. Conclusions. The findings of this prospective cohort study suggest that higher level of high-sensitivity CRP is an independent risk factor for hyperuricemia in Chinese, especially in women.


Author(s):  
Yea-Chan Lee ◽  
Da-Hye Son ◽  
Yu-Jin Kwon

Serum high-sensitivity C-reactive protein (hsCRP) and serum uric acid (SUA) are biomarkers that predict chronic inflammation and cardiovascular dysfunction. Therefore, we aimed to investigate the association between sleep duration, hsCRP, and SUA in Korean women. Cross-sectional data from the Seventh Korea National Health and Nutrition Examination Survey was analyzed. The odds ratio (OR) and 95% confidence intervals (CIs) for an association between higher hsCRP (>2.0 mg/L) or higher SUA (>5.6 mg/dL) and sleep duration were calculated using multiple logistic regression analyses after adjusting for potential confounders. In total, 6151 women were included in the analysis. There was a U-shaped relationship between continuous sleep duration, hsCRP, and SUA. Compared to those who slept for 7–8 h, the ORs (95% CIs) for higher hsCRP were 1.43 (0.95–2.16) in short sleepers and 1.64 (1.09–2.48) in long sleepers after adjusting for confounders. Compared with those who slept for 7–8 h, the ORs (95% CIs) for higher SUA were 1.54 (1.04–2.26) in short sleepers and 1.94 (1.27–2.96) in long sleepers after adjusting for confounders. We found a U-shaped association between sleep duration, hsCRP, and SUA in Korean women. 7–8 h sleep was associated with lower level of hsCRP and SUA in Korean women.


BMJ Open ◽  
2014 ◽  
Vol 4 (11) ◽  
pp. e006071 ◽  
Author(s):  
Yue Leng ◽  
Sara Ahmadi-Abhari ◽  
Nick W J Wainwright ◽  
Francesco P Cappuccio ◽  
Paul G Surtees ◽  
...  

Respirology ◽  
2008 ◽  
Vol 13 (5) ◽  
pp. 664-669 ◽  
Author(s):  
Fen-Hong QIAN ◽  
Qian ZHANG ◽  
Lin-Fu ZHOU ◽  
Hua LIU ◽  
Mao HUANG ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document