scholarly journals COPD assessment test and severity of airflow limitation in patients with asthma, COPD, and asthma–COPD overlap syndrome

2016 ◽  
pp. 479 ◽  
Author(s):  
Kazuyoshi Kurashima ◽  
Yotaro Takaku ◽  
Chie Ohta ◽  
Noboru Takayanagi ◽  
Tsutomu Yanagisawa ◽  
...  
Keyword(s):  
Overlap Syndrome ◽  
Airflow Limitation ◽  
Copd Assessment Test

scholarly journals What is asthma−COPD overlap syndrome? Towards a consensus definition from a round table discussion

2016 ◽  
Vol 48 (3) ◽  
pp. 664-673 ◽  
Author(s):  
Don D. Sin ◽  
Marc Miravitlles ◽  
David M. Mannino ◽  
Joan B. Soriano ◽  
David Price ◽  
...  
Keyword(s):  
Management Strategies ◽  
Round Table ◽  
Case Definition ◽  
Overlap Syndrome ◽  
Airflow Limitation ◽  
Round Table Discussion ◽  
Chronic Obstructive ◽  
Consensus Definition ◽  
Key Features ◽  
Definition Of

Patients with asthma–chronic obstructive pulmonary disease overlap syndrome (ACOS) have been largely excluded from pivotal therapeutic trials and, as a result, its treatment remains poorly defined and lacking firm evidence. To date, there is no universally accepted definition of ACOS, which has made it difficult to understand its epidemiology or pathophysiology. Despite many uncertainties, there is emerging agreement that some of the key features of ACOS include persistent airflow limitation in symptomatic individuals 40 years of age and older, a well-documented history of asthma in childhood or early adulthood and a significant exposure history to cigarette or biomass smoke. In this perspective, we propose a case definition of ACOS that incorporates these key features in a parsimonious algorithm that may enable clinicians to better diagnose patients with ACOS and most importantly enable researchers to design therapeutic and clinical studies to elucidate its epidemiology and pathophysiology and to ascertain its optimal management strategies.

Is COPD Assessment Test score better correlated with airflow limitation or Hyperinflation?

2021 ◽  
Author(s):  
Soumaya Khaldi ◽  
Khouloud Kchaou ◽  
Asma Chaker ◽  
Salma Mokaddem ◽  
Saloua Ben Khamsa Jameleddine
Keyword(s):  
Test Score ◽  
Airflow Limitation ◽  
Copd Assessment Test

Asthma and COPD Overlap Syndrome (ACOS)

2015 ◽  
Vol 69 (1) ◽  
pp. 8-11
Author(s):  
Deska Dimitrievska ◽  
Marija Zdraveska ◽  
Dejan Todevski ◽  
Elena Janeva ◽  
Suzana Arbutina ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lung Function ◽  
Randomized Clinical Trials ◽  
Significant Proportion ◽  
Overlap Syndrome ◽  
Airflow Limitation ◽  
Rapid Decline ◽  
Chronic Obstructive ◽  
Acute Exacerbations

Abstract Asthma and chronic obstructive pulmonary disease (COPD) have traditionally been viewed as distinct clinical entities. Recently, however, much attention has been focused on patients with overlapping features of both asthma and COPD: those with asthma COPD overlap syndrome (ACOS). A significant proportion of patients who present with symptoms of a chronic airways disease have features of both asthma and COPD. Several diagnostic terms, most including the word “overlap”, have been applied to such patients, and the topic has been extensively reviewed. However, there is no generally agreed term or defining features for this category of chronic airflow limitation, although a definition based upon consensus has been published for overlap in patients with existing COPD. In spite of these uncertainties, there is broad agreement that patients with features of both asthma and COPD experience frequent exacerbations, have poor quality of life, a more rapid decline in lung function and high mortality, and consume a disproportionate amount of healthcare resources than asthma or COPD alone. ACOS accounts for approximately 15-25% of the obstructive airway diseases and patients experience worse outcomes compared to asthma or COPD alone. Patients with ACOS often have the combined risk factors of smoking and atopy, are generally younger than patients with COPD and experience acute exacerbations with higher frequency and greater severity than in COPD alone. Pharmacotherapeutic considerations require an integrated approach, first to identify the relevant clinical phenoltype( s), then to determine the best available therapy. The authors discuss the array of existing and emerging classes of drugs which patients with ACOS could benefit from and share their therapeutic approach. A consensus international definition of ACOS is needed to design prospective. Randomized clinical trials are necessary to evaluate specific influence of drug interventions on important outcomes such as lung function, acute exacerbations, quality of life and mortality.

scholarly journals Evaluation of the Persian Transcript of the COPD Assessment Test in the Measurement of COPD Health Status in Iranian COPD Patients

2015 ◽  
Vol 8 (5) ◽  
pp. 225 ◽  
Author(s):  
Alireza Azargon ◽  
Mohammadreza Gholami ◽  
Ali Farhadi ◽  
Maryam Hadi Chegni ◽  
Abolfazl Zendedel
Keyword(s):  
Disease Severity ◽  
Chronic Obstructive Lung Disease ◽  
Airway Disease ◽  
Cross Sectional Study ◽  
Airflow Limitation ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Copd Assessment Test ◽  
The Relationship ◽  
Obstruction Severity

<p><strong>AIM:</strong> Chronic obstructive pulmonary disease is a completely irreversible obstructive airway disease. The COPD assessment test (CAT) is one of the standard methods for the clinical assessment of the disease, which is translated into Persian. This study investigated the reliability of the test and its relationship with the severity of the disease.</p><p><strong>METHODS:</strong> In this cross-sectional study, 120 patients filled out the Persian transcript of the test. After two weeks, the patients filled out the CAT test again. Obstruction severity was determined for all the patients using spirometry, and the patients were categorized into four groups according to the Global Initiative for Chronic Obstructive Lung Disease criteria. The relationship between the test scores and the disease severity wan validated.</p><p><strong>RESULTS:</strong> The mean age of the patients was 51.5 years. The Cronbach's alpha coefficient of the Persian transcript of the test was 0.872 in the first time, and 0.885 in the second time. Intragroup reliability, test re-test and intragroup correlations were significant for all the questions (&lt;0.001). The relationship between the test mean score and obstruction severity was significant, and the correlation between disease categorization in accordance with obstruction severity and categorization according to the test score was significant as well.</p><p><strong>CONCLUSION:</strong> The Persian transcript of the assessment test for COPD was reliable and is directly related to the disease severity according to airflow limitation.</p>

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