scholarly journals Prognostic value of subcutaneous adipose tissue volume in hepatocellular carcinoma treated with transcatheter intra-arterial therapy

2018 ◽  
Vol Volume 10 ◽  
pp. 2231-2239 ◽  
Author(s):  
Takamasa Kobayashi ◽  
Hirokazu Kawai ◽  
Oki Nakano ◽  
Satoshi Abe ◽  
Hiroteru Kamimura ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Prognostic Value ◽  
Tissue Volume ◽  
Adipose Tissue Volume ◽  
Subcutaneous Adipose

Total and segmental subcutaneous adipose tissue volume measured by ultrasound

1996 ◽  
Vol 28 (7) ◽  
pp. 908-912 ◽  
Author(s):  
TAKASHI ABE ◽  
FUMIKO TANAKA ◽  
YASUO KAWAKAMI ◽  
KOHKI YOSHIKAWA ◽  
TETSUO FUKUNAGA
Keyword(s):  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Tissue Volume ◽  
Adipose Tissue Volume ◽  
Subcutaneous Adipose

scholarly journals Computed Tomography Measurement of Hepatic Steatosis: Prevalence of Hepatic Steatosis in a Canadian Population

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Malcolm M. Wells ◽  
Zhe Li ◽  
Bryan Addeman ◽  
Charles A. McKenzie ◽  
Amol Mujoomdar ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Adipose Tissue ◽  
Liver Disease ◽  
Hepatic Steatosis ◽  
Subcutaneous Adipose Tissue ◽  
Chart Review ◽  
Retrospective Chart Review ◽  
Canadian Population ◽  
Adipose Tissue Volume ◽  
Subcutaneous Adipose

Background/Aims. Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease that can progress to cirrhosis and hepatocellular carcinoma. This retrospective chart review investigated the incidence of hepatic steatosis in London, Ontario, Canada.Methods. A retrospective chart review was performed on emergency room (ER) patients undergoing nonscheduled computed tomography (CT) imaging over a six-month period in London, Ontario. CT images and reports were examined to determine presence of steatosis. Analyses of the electronic chart for a period of six months following the CT and communication with the patients’ family doctors were used to determine if there was follow-up. Waist circumference, subcutaneous fat depth, and abdominal fat volumes were calculated.Results. 48/450 patients meeting inclusion criteria were identified by radiology as having steatosis, with 34/40 (85%) family physicians unaware of the finding. 24.7% (100/405) of patients met standard CT criteria for steatosis, 40 of which were reported by the radiologist. Waist circumference, subcutaneous adipose tissue depth, subcutaneous adipose tissue volume, and visceral adipose tissue volume were significantly associated with steatosis.Conclusions. The hepatic steatosis prevalence we report is the first reported in a Canadian population. Early identification of steatosis will become more important as new pharmacologic therapies arise.

scholarly journals Rapid Depletion of Subcutaneous Adipose Tissue during Sorafenib Treatment Predicts Poor Survival in Patients with Hepatocellular Carcinoma

Cancers ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1795
Author(s):  
Kenji Imai ◽  
Koji Takai ◽  
Takao Miwa ◽  
Daisuke Taguchi ◽  
Tatsunori Hanai ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Skeletal Muscle ◽  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Proportional Hazards Model ◽  
Cox Proportional Hazards ◽  
Cox Proportional Hazards Model ◽  
Sorafenib Treatment ◽  
Skeletal Muscle Index ◽  
Subcutaneous Adipose

The aim of this study was to assess the annualized changes in body composition, including skeletal muscle, subcutaneous adipose tissue (SAT), and visceral adipose tissue (VAT) before, during, and after sorafenib treatment in patients with hepatocellular carcinoma (HCC). This retrospective study evaluated 61 HCC patients treated with sorafenib. Annualized changes (Δ; cm2/m2/year) in skeletal muscle index (SMI), SAT index (SATI), and VAT index (VATI), which were defined as the cross-sectional areas (cm2) of those areas on computed tomography normalized by the square of one’s height (m2), before (pre), during (during), and after (post) sorafenib treatment, were calculated. Patients within the 20th percentile cutoffs for these indices were classified into the rapid depletion group and the effects of these values on survival were analyzed using the Kaplan-Meier analysis and Cox proportional-hazards model. Annualized depletion rates of SMI (ΔSMIpre: −3.5, ΔSMIduring: −3.5, ΔSMIpost: −8.0) and VATI (ΔVATIpre: −3.2, ΔVATIduring: −2.8, ΔVATIpost: −15.1) accelerated after the cancellation of sorafenib, whereas that of SATI (ΔSATIpre: −4.8, ΔSATIduring; −7.6, ΔSATIpost; −8.0) had already accelerated during sorafenib treatment. Patients with rapid depletion of ΔSATIduring experienced significantly worse survival rates (p < 0.001), and it was an independent predictor of survival (p = 0.009), together with therapeutic effect (p < 0.001). Rapid depletion of SAT during sorafenib treatment can be used to predict survival in patients with HCC.

Subcutaneous adipose tissue is a predictor of survival in patients with hepatocellular carcinoma

2018 ◽  
Vol 68 ◽  
pp. S423
Author(s):  
L. von Koeckritz ◽  
P. Kolly ◽  
M. Maurer ◽  
S.-E. Birgit ◽  
A. Berzigotti ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Adipose Tissue ◽  
Subcutaneous Adipose Tissue ◽  
Subcutaneous Adipose
Sign in / Sign up

Export Citation Format

Share Document