scholarly journals Bone mass density estimation: Archimede’s principle versus automatic X-ray histogram and edge detection technique in ovariectomized rats treated with germinated brown rice bioactives

2013 ◽  
pp. 1421 ◽  
Author(s):  
Sani Ismaila Muhammad ◽  
Maznah Ismail ◽  
Rozi Mahmud ◽  
Maher Faik Esmaile ◽  
Zuki Abu Bakar Zakaria
Keyword(s):  
Bone Mass ◽  
Edge Detection ◽  
Density Estimation ◽  
Mass Density ◽  
Brown Rice ◽  
Detection Technique ◽  
Ovariectomized Rats ◽  
Bone Mass Density ◽  
Germinated Brown Rice ◽  
X Ray

scholarly journals Autoimmunological serum parameters and bone mass density in premature ovarian insufficiency: a retrospective cohort study

2020 ◽  
Author(s):  
Klara Beitl ◽  
Klara Rosta ◽  
Nina Poetsch ◽  
Manuel Seifried ◽  
Daniel Mayrhofer ◽  
...  
Keyword(s):  
Bone Mass ◽  
Retrospective Cohort ◽  
Mass Density ◽  
Dual Energy ◽  
Premature Ovarian Insufficiency ◽  
Bone Mass Density ◽  
Ovarian Insufficiency ◽  
X Ray ◽  
T Score ◽  
Normal Women

Abstract Purpose It is still not clear whether to screen women with primary premature ovarian insufficiency for autoimmunity. Moreover, a possible association of autoimmunity with decreased bone mass density in premature ovarian insufficiency patients has not been evaluated. Thus, the objectives of this study were to review our experience with the use of an autoimmune screening panel in premature ovarian insufficiency women and to focus on bone mass density. Methods In a retrospective cohort study, 76 chromosomally normal women with primary premature ovarian insufficiency were included. The main outcome parameters were the results of an autoimmune screening panel and of dual-energy X-ray absorptiometry. Results Median age was 33 years. Sixty percent of premature ovarian insufficiency patients revealed abnormal dual-energy X-ray absorptiometry results (minimal T-score < −1.0). Any signs of autoimmunity were found in 21 women (36.2%). The most frequent abnormal results were increased thyroperoxidase antibodies (24.1%) and thyroglobulin antibodies (20.7%). A longer duration of amenorrhea (β = −0.015; p = 0.007), any abnormality during autoimmune screening (β = −0.940; p = 0.010), and a lower body mass index (β = −0.057; p = 0.036) were associated with a lower minimal T-score. Conclusion In chromosomally normal women with primary premature ovarian insufficiency, the prevalence of autoimmunity and decreased bone mass density seem high. Our data highlight the association between autoimmune abnormalities and decreased dual-energy X-ray absorptiometry results.

scholarly journals The Influence of Statins on Bone Tissue in Ovariectomized Rats

2018 ◽  
Vol 1 (1) ◽  
Keyword(s):  
Bone Density ◽  
Mass Density ◽  
Dual Energy ◽  
Bone Architecture ◽  
Female Rats ◽  
Ovariectomized Rats ◽  
Bone Mass Density ◽  
X Ray ◽  
Skeletal Disease ◽  
Coa Reductase

Objectives: Osteoporosis is a silent, progressive, systemic skeletal disease characterized by impaired bone architecture with decreased bone mass density, affecting mainly women. Statins, inhibitors of HMG-CoA-reductase, seem to interfere with bone formation exerting anabolic and anti-resorptive effect. The aim of the present study is to investigate the effect of simvastatin on size parameters and bone density of mandible and femur, in an ovariectomized rat model of osteoporosis. Methods: 50 Wistar female rats were randomized in five groups (n=10). Groups 1, 2,3 were ovariectomized, 4 and 5 serve as controls. Groups 2, 3 and 5 were treated with simvastatin (0.5mg/kg/daily per os). Size parameters of the isolated femur, mandible and uterus, BMD via dual energy X-Ray absorptiometry (DEXA) and serum interleukin-13 (IL-13) were estimated. Results: DEXA results showed significant decrease of BMD in ovariectomized group / controls while statins treatment decreased the severity of BMD lose. The serum IL-13, as osteogenesis index, seems to be positively influenced by statins treatment. Conclusions: Statins treatment seems to restore the decreased femur and mandible parameters and uterus weight in experimental menopause following ovariectomy.

scholarly journals Selection of risk assessment methods for osteoporosis screening in postmenopausal women with low-energy fractures: A comparison of fracture risk assessment tool, digital X-ray radiogrammetry, and dual-energy X-ray absorptiometry

2022 ◽  
Vol 10 ◽  
pp. 205031212110734
Author(s):  
Mischa Woisetschläger ◽  
Simona Chisalita ◽  
Marta Vergara ◽  
Anna Spångeus
Keyword(s):  
Risk Assessment ◽  
Bone Mass ◽  
Fracture Risk ◽  
Assessment Tool ◽  
Mass Density ◽  
Fracture Risk Assessment ◽  
Bone Mass Density ◽  
X Ray ◽  
Fracture Risk Assessment Tool ◽  
Fracture Liaison

Objectives: Fracture liaison services are designed to identify patients needing osteoporosis treatment after a fracture. Some fracture liaison service designs involve a prescreening step, for example, fracture risk assessment tool (FRAX®). Another possible prescreening tools are bone mass density assessment in the acute setting. The aim of this study was to assess the effectiveness of prescreening tools. Methods: In the present prospective cohort study, women aged >55 years with a radius fracture were included. Patients were recruited at the emergency department after experiencing their fracture. All patients performed fracture risk assessment by fracture risk assessment tool, and bone mass density assessment by digital X-ray radiogrammetry and dual-energy X-ray absorptiometry (prescreening steps) as well as full routine evaluation at the osteoporosis unit (endpoint). The main outcome measures were sensitivity, specificity, predictive values, and area under the curve. Results: Forty-one women were recruited (mean age: 70 ± 8 years). Of these, 54% fulfilled the treatment indication criteria of osteoporosis after a full examination. Fracture risk assessment tool without bone mass density (cutoff ⩾ 15%) for prescreening patients had a high sensitivity (90%) but a low area under the curve (0.50) and specificity (16%). The highest area under the curve (0.73) was found prescreening with bone mass density assessment (dual-energy X-ray absorptiometry or digital X-ray radiogrammetry) having a sensitivity of 59%–86% and specificity of 61%–90%. Conclusion: This study, though small, raises questions regarding the effectiveness of using a prescreening step in fracture liaison services for high-risk individuals. In this cohort, FRAX® without bone mass density had a low precision, with a risk of both underestimating and overestimating patients requiring treatment. Bone mass density assessment in the acute setting could improve the precision of prescreening. Further investigations on the effectiveness and health economics of prescreening steps in fracture liaison services are needed.

scholarly journals The influence of bone quality on radiological outcome in 50 consecutive acetabular fractures treated with a pre-contoured anatomic suprapectineal plate

2021 ◽  
Author(s):  
Maximilian J. Hartel ◽  
Tareq Naji ◽  
Florian Fensky ◽  
Frank O. Henes ◽  
Darius M. Thiesen ◽  
...  
Keyword(s):  
Total Hip Arthroplasty ◽  
Bone Mass ◽  
Bone Quality ◽  
Hip Arthroplasty ◽  
Mass Density ◽  
Acetabular Fractures ◽  
Bone Mass Density ◽  
Radiological Outcome ◽  
Total Hip ◽  
The Impact

Abstract Purpose To investigate the range of indications of an anatomical-preshaped three-dimensional suprapectineal plate and to assess the impact of the bone mass density on radiologic outcomes in different types of acetabular fractures. Patients and methods A consecutive case series of 50 acetabular fractures (patient age 69 ± 23 years) treated with suprapectineal anatomic plates were analyzed in a retrospective study. The analysis included: Mechanism of injury, fracture pattern, surgical approach, need for additional total hip arthroplasty, intra- or postoperative complications, as well as bone mass density and radiological outcome on postoperative computed tomography. Results Most frequently, anterior column fracture patterns with and without hemitransverse components as well as associated two column fractures were encountered. The anterior intrapelvic approach (AIP) was used in 98% (49/50) of the cases as primary approach with additional utilization of the first window of the ilioinguinal approach in 13/50 cases (26%). Determination of bone density revealed impaired bone quality in 70% (31/44). Postoperative steps and gaps were significantly greater in this subgroup (p < 0.05). Fracture reduction quality for postoperative steps revealed anatomic results in 92% if the bone quality was normal and in 46% if impaired (p < 0.05). In seven cases (14%), the plate was utilized in combination with acute primary arthroplasty. Conclusion A preshaped suprapectineal plate provides good radiological outcomes in a variety of indications in a predominantly geriatric cohort. Impaired bone quality has a significantly higher risk of poor reduction results. In cases with extensive joint destruction, the combination with total hip arthroplasty was a valuable option.

Relationship between bone mass density and tensile strength of the skin in women

2001 ◽  
Vol 31 (8) ◽  
pp. 731-735 ◽  
Author(s):  
G. E. Piérard ◽  
C. Piérard-Franchimont ◽  
S. Vanderplaetsen ◽  
N. Franchimont ◽  
U. Gaspard ◽  
...  
Keyword(s):  
Tensile Strength ◽  
Bone Mass ◽  
Mass Density ◽  
Bone Mass Density

scholarly journals Effect of ghrelin on bone mass density: The InChianti study

Bone ◽  
2011 ◽  
Vol 49 (2) ◽  
pp. 257-263 ◽  
Author(s):  
Nicola Napoli ◽  
Claudio Pedone ◽  
Paolo Pozzilli ◽  
Fulvio Lauretani ◽  
Stefania Bandinelli ◽  
...  
Keyword(s):  
Bone Mass ◽  
Mass Density ◽  
Bone Mass Density
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