scholarly journals Transcriptome Analysis of Pseudomonas aeruginosa Biofilm Following the Exposure to Malaysian Stingless Bee Honey

2021 ◽  
Vol Volume 14 ◽  
pp. 1-11
Author(s):  
Nesrin Seder ◽  
Mohd Hilmi Abu Bakar ◽  
Walid Salem Abu Rayyan
2020 ◽  
Vol Volume 13 ◽  
pp. 155-169
Author(s):  
Jun Hong ◽  
Honghao Jiang ◽  
Jianye Hu ◽  
Lianzhe Wang ◽  
Ruifang Liu

2010 ◽  
Vol 12 (12-13) ◽  
pp. 1042-1050 ◽  
Author(s):  
Amanda Bryan ◽  
Chase Watters ◽  
Lars Koenig ◽  
Eunseog Youn ◽  
Aaron Olmos ◽  
...  

Microbiology ◽  
2018 ◽  
Vol 164 (4) ◽  
pp. 551-562 ◽  
Author(s):  
Jon Shuman ◽  
Tyler Xavier Giles ◽  
Leslie Carroll ◽  
Kenji Tabata ◽  
Austin Powers ◽  
...  

2019 ◽  
Vol 62 (2) ◽  
pp. 97-100
Author(s):  
Taif Shah ◽  
Niyaz Ali ◽  
Zahir Shah ◽  
Azam Hayat

The current study was conducted to determine the antibacterial activity of 50 crude and processed honey samples produced by Apis mellifera and stingless bee. All the honey samples were collected from different places of Districts Dir, Swat and Oghi of Khyber Pakhtunkhwa Province, Pakistan and were tested against the six ATCC bacterial species including E. coli ATCC number 25922, Pseudomonas aeruginosa ATCC number 27853, Staphylococcus aureus ATCC number 6538, Enterococcus faecalis ATCC number 19433, Salmonella typhi ATCC number 19943 and Klebsiella pneumoniae ATCC number 27736. The honey samples showed variable zones of inhibition by using Agar well plate technique. E. coli showed 17-23 mm, S. typhi 31-37 mm, E. faecalis 28 mm, P. aeruginosa 14-15 mm, K. pneumoniae 20-24 mm and Staph. aureus 19-25 mm. Most of the honey samples used in this study showed broad spectrum antibacterial activity.


2004 ◽  
Vol 186 (1) ◽  
pp. 248-252 ◽  
Author(s):  
Marco Palma ◽  
Darrow DeLuca ◽  
Stefan Worgall ◽  
Luis E. N. Quadri

ABSTRACT Pseudomonas aeruginosa must often overcome a high concentration of oxidants to successfully infect the human host. We report here the results of a transcriptome profiling comparing cells treated with H2O2 and untreated controls. The data indicate that the early response of P. aeruginosa to H2O2 consists of an upregulation of protective mechanisms and a downregulation of primary metabolism.


2003 ◽  
Vol 185 (7) ◽  
pp. 2066-2079 ◽  
Author(s):  
Martin Schuster ◽  
C. Phoebe Lostroh ◽  
Tomoo Ogi ◽  
E. P. Greenberg

ABSTRACT There are two interrelated acyl-homoserine lactone quorum-sensing-signaling systems in Pseudomonas aeruginosa. These systems, the LasR-LasI system and the RhlR-RhlI system, are global regulators of gene expression. We performed a transcriptome analysis to identify quorum-sensing-controlled genes and to better understand quorum-sensing control of P. aeruginosa gene expression. We compared gene expression in a LasI-RhlI signal mutant grown with added signals to gene expression without added signals, and we compared a LasR-RhlR signal receptor mutant to its parent. In all, we identified 315 quorum-induced and 38 quorum-repressed genes, representing about 6% of the P. aeruginosa genome. The quorum-repressed genes were activated in the stationary phase in quorum-sensing mutants but were not activated in the parent strain. The analysis of quorum-induced genes suggests that the signal specificities are on a continuum and that the timing of gene expression is on a continuum (some genes are induced early in growth, most genes are induced at the transition from the logarithmic phase to the stationary phase, and some genes are induced during the stationary phase). In general, timing was not related to signal concentration. We suggest that the level of the signal receptor, LasR, is a critical trigger for quorum-activated gene expression. Acyl-homoserine lactone quorum sensing appears to be a system that allows ordered expression of hundreds of genes during P. aeruginosa growth in culture.


Sign in / Sign up

Export Citation Format

Share Document