Randomized trial of oral versus intravenous acetaminophen for postoperative pain control

2018 ◽  
Vol 75 (6) ◽  
pp. 367-375 ◽  
Author(s):  
Skip R. Hickman ◽  
Kathleen M. Mathieson ◽  
Lynne M. Bradford ◽  
Casey D. Garman ◽  
Richard W. Gregg ◽  
...  
Keyword(s):  
Postoperative Pain ◽  
Randomized Trial ◽  
Pain Control ◽  
Postoperative Pain Control ◽  
Intravenous Acetaminophen

Preoperative Caesarean Delivery Intravenous Acetaminophen Treatment for Postoperative Pain Control

2019 ◽  
Vol 39 (2) ◽  
pp. 109-110
Author(s):  
C.V. Towers ◽  
S. Shelton ◽  
J. van Nes ◽  
E. Gregory ◽  
E. Liske ◽  
...  
Keyword(s):  
Postoperative Pain ◽  
Pain Control ◽  
Caesarean Delivery ◽  
Postoperative Pain Control ◽  
Intravenous Acetaminophen

Review of Intravenous Acetaminophen for Analgesia in the Postoperative Setting

2021 ◽  
pp. 000313482198905
Author(s):  
Danielle M. Tompkins ◽  
Arielle DiPasquale ◽  
Michelle Segovia ◽  
Stephen M. Cohn
Keyword(s):  
Postoperative Pain ◽  
Clinical Benefit ◽  
Pain Control ◽  
Opioid Analgesic ◽  
Postoperative Pain Control ◽  
Intravenous Acetaminophen ◽  
Primary Literature ◽  
Significant Efficacy ◽  
Postoperative Setting ◽  
Type Of Surgery

Background Acetaminophen is a non-opioid analgesic commonly utilized for pain control after several types of surgical procedures. Methods This scoping primary literature review provides recommendations for intravenous (IV) acetaminophen use based on type of surgery. Results Intravenous acetaminophen has been widely studied for postoperative pain control and has been compared to other agents such as NSAIDs, opioids, oral/rectal acetaminophen, and placebo. Some of the procedures studied include abdominal, gynecologic, orthopedic, neurosurgical, cardiac, renal, and genitourinary surgeries. Results of these studies have been conflicting and largely have not shown consistent clinical benefit. Conclusion Overall, findings from this review did not support the notion that IV acetaminophen has significant efficacy for postoperative analgesia. Given the limited clinical benefit of IV acetaminophen, especially when compared to the oral or rectal formulations, use is generally not justifiable.

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