scholarly journals Relationship of growth differentiation factor-15 with aortic stiffness in essential hypertension

2019 ◽  
Vol 5 (7) ◽  
pp. FSO406 ◽  
Author(s):  
Erdoğan Sökmen ◽  
Cahit Uçar ◽  
Serkan Sivri ◽  
Mustafa Çelik ◽  
Kenan Güçlü
Keyword(s):  
Essential Hypertension ◽  
Aortic Stiffness ◽  
Aortic Distensibility ◽  
The Other ◽  
Aortic Elasticity ◽  
Differentiation Factor ◽  
Echocardiographic Parameters ◽  
Relationship Of ◽  
The Relationship ◽  
Aortic Strain

Aim: We aimed to assess the relationship between echocardiographic parameters of aortic elasticity, namely aortic strain, aortic distensibility and aortic β-index, and serum growth differentiation factor (GDF)-15 in patients with newly diagnosed essential hypertension (HT). Methods: Grade-1 HT patients (n = 50), grade-2 HT (n = 70) patients and 35 healthy controls were included. Results: GDF-15 was greater in grade-2 HT group compared with the other groups. All aortic elasticity parameters were worse in grade-2 HT group compared with the other groups. GDF-15 correlated positively with E/E′ ratio (the ratio of transmitral E velocity to mean diastolic mitral annular velocity) and β-index; and aortic strain and aortic distensibility correlated negatively with serum GDF-15. β-index, aortic diastolic diameter and diastolic blood pressure were independently associated with GDF-15. Conclusion: GDF-15 may be utilized in the prediction of increased aortic stiffness.

The Relationship Between Serum Endocan Level and Aortic Elastic Properties in Patients With Newly Diagnosed Essential Hypertension

Angiology ◽  
2019 ◽  
Vol 70 (7) ◽  
pp. 662-668 ◽  
Author(s):  
Mustafa Çelik ◽  
Erdoğan Sökmen ◽  
Serkan Sivri ◽  
Cahit Uçar ◽  
Rukiye Nar ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Elastic Properties ◽  
Aortic Stiffness ◽  
Surrogate Marker ◽  
Aortic Distensibility ◽  
Stiffness Index ◽  
Newly Diagnosed ◽  
The Relationship ◽  
Aortic Elastic Properties ◽  
Aortic Strain

Endothelial dysfunction plays role in the generation of both essential hypertension (EH) and aortic stiffness. We evaluated the relationship between serum endocan level and aortic elastic properties (AEPs) assessed with the aortic strain, aortic distensibility, and aortic stiffness index by echocardiography. Newly diagnosed EH patients (n = 67) and controls (n = 70) were included in the study. The EH group was subdivided into stage 1 and 2 EH groups. A higher endocan level was found in the EH group, compared to the controls (34.2 ± 13.0 vs 24.1 ± 7.3 ng/mL, respectively, P < .001). All the AEP parameters were worse in the EH group, compared to the controls. Further, endocan levels correlated with aortic distensibility ( r = −0.305, P < .001) and aortic strain ( r = −0.181, P = .038), but not with aortic stiffness index ( r = 0.162, P = .064) in the whole study population. Aortic elastic properties deteriorate and serum endocan level increases in patients with EH. Moreover, serum endocan level shows a correlation with deteriorated AEPs, and hence may a surrogate marker of escalating aortic stiffness in patients with newly diagnosed EH.

EVALUATION OF AORTIC ELASTICITY ON THE PRIMARY HYPERTENSIVES BY ECHOCARDIOGRAPHY

2011 ◽  
pp. 123-130
Author(s):  
Thi Hieu Dung Nguyen ◽  
Thi Thuy Hang Nguyen
Keyword(s):  
Left Ventricular Mass ◽  
Aortic Stiffness ◽  
Left Ventricular Mass Index ◽  
Aortic Distensibility ◽  
Left Ventricular ◽  
Control Group ◽  
Ventricular Mass Index ◽  
Aortic Elasticity ◽  
Ventricular Mass ◽  
Aortic Strain

Hypertension, affecting directly cardiovascular structure and function, reduces aortic elasticity, which leads to early reflect wave in central aortic. Studying on aortic elasticity in the primary hypertensives by echocardiography contributes to evaluate cardiovascular changes. Aims: was to estimate the indexes of aortic elasticity in the primary hypertensives and the correlation between them and left ventricular mass index. Subjects and Methods: this study was carried on 30 primary hypertensives, mean age: 47,43 ± 5,83 and compared with normotensive control group. They are all under echocardiography to measure systolic aortic diameter and diastolic aortic diameter, left ventricular mass, and left ventricular mass index. Then, assess the indexes such as: aortic strain, aortic stiffness, aortic distensibility and correlation between them and left ventricular mass index. Results: Aortic stiffness is significantly higher and aortic strain and aortic distensibility are significantly lower in the hypertensives than the normotensive control group (p< 0,05). There are negative correlation between left ventricular mass index and both aortic strain and aortic distensibility. In contrast, there is positive correlation between aortic stiffness and left ventricular mass index (p < 0,05). Conclusion: Aortic elasticity in the primary hypertensives decreases, which has repercussions on left ventricular mass, so it is a predictor of cardiovascular risk factors.

scholarly journals On Newcomb's method of investigating periodicities and its application to Brückner's weather cycle

1914 ◽  
Vol 90 (619) ◽  
pp. 349-355
Keyword(s):  
Thermal Radiation ◽  
The Other ◽  
New Method ◽  
Critical Examination ◽  
Numerical Work ◽  
Average Value ◽  
Other Hand ◽  
Relationship Of ◽  
The Relationship ◽  
Great Simplicity

During the last few years of his life Prof. Simon Newcomb was keenly interested in the problem of periodicities, and devised a new method for their investigation. This method is explained, and to some extent applied, in a paper entitled "A Search for Fluctuations in the Sun's Thermal Radiation through their Influence on Terrestrial Temperature." The importance of the question justifies a critical examination of the relationship of the older methods to that of Newcomb, and though I do not agree with his contention that his process gives us more than can be obtained from Fourier's analysis, it has the advantage of great simplicity in its numerical work, and should prove useful in a certain, though I am afraid, very limited field. Let f ( t ) represent a function of a variable which we may take to be the time, and let the average value of the function be zero. Newcomb examines the sum of the series f ( t 1 ) f ( t 1 + τ) + f ( t 2 ) f ( t 2 + τ) + f ( t 3 ) f ( t 3 + τ) + ..., where t 1 , t 2 , etc., are definite values of the variable which are taken to lie at equal distances from each other. If the function be periodic so as to repeat itself after an interval τ, the products are all squares and each term is positive. If, on the other hand, the periodic time be 2τ, each product will be negative and the sum itself therefore negative. It is easy to see that if τ be varied continuously the sum of the series passes through maxima and minima, and the maxima will indicated the periodic time, or any of its multiples.

scholarly journals Physical Activity and Psychological Well-Being: Testing Alternative Sociological Interpretations

1990 ◽  
Vol 7 (4) ◽  
pp. 329-346 ◽  
Author(s):  
William McTeer ◽  
James E. Curtis
Keyword(s):  
Physical Activity ◽  
Socioeconomic Status ◽  
Social Interaction ◽  
Physical Fitness ◽  
Well Being ◽  
The Other ◽  
Positive Zero ◽  
Psychological Well Being ◽  
Relationship Of ◽  
The Relationship

This study examines the relationship between physical activity in sport and feelings of well-being, testing alternative interpretations of the relationship between these two variables. It was expected that there would be positive relationships between physical activity on the one hand and physical fitness, feelings of well-being, social interaction in the sport and exercise environment, and socioeconomic status on the other hand. It was also expected that physical fitness, social interaction, and socioeconomic status would be positively related to psychological well-being. Further, it was expected that any positive zero-order relationship of physical activity and well-being would be at least in part a result of the conjoint effects of the other variables. The analyses were conducted separately for the male and female subsamples of a large survey study of Canadian adults. The results, after controls, show a modest positive relationship of physical activity and well-being for males but no such relationship for females. The predicted independent effects of the control factors obtained for both males and females. Interpretations of the results are discussed.

THE RELATIONSHIP OF THE SODIUM, POTASSIUM, AND CHLORIDE CONCENTRATION OF THE FEEDING TO THE WEIGHT GAIN OF PREMATURE INFANTS

PEDIATRICS ◽  
1962 ◽  
Vol 30 (6) ◽  
pp. 909-916
Author(s):  
Herbert I. Goldman ◽  
Samuel Karelitz ◽  
Hedda Acs ◽  
Eli Seifter
Keyword(s):  
Weight Gain ◽  
Sodium Chloride ◽  
Human Milk ◽  
Premature Infants ◽  
Chloride Concentration ◽  
The Other ◽  
Milk Formula ◽  
Sodium Potassium ◽  
Relationship Of ◽  
The Relationship

One hundred four healthy premature infants, of birth weight 1,000 to 1,800 gm, were fed one of five feedings: (1) human milk; (2) human milk plus 13 meq/l of sodium chloride; (3) human milk plus 13 meq/l of sodium chloride and 18 meq/l of potassium chloride; (4) a half-skimmed cows milk formula; and (5) a partially-skimmed vegetable oil, cows milk formula. The infants fed any of the three human milk formulas gained weight at a slower rate than the infants fed either of the two cows milk formulas. Infants whose diets were changed from unmodified human milk to the half-skimmed cows milk gained large amounts of weight, and at times were visibly edematous. Infants whose diets were changed from the human milks with added sodium chloride, to the half-skimmed cows milk, gained lesser amounts of weight and did not become edematous. The infants fed the two cows milk diets gained similar amounts of weight, although one diet provided 6.5 gm/kg/day, the other 3.1 gm/kg/day of protein.

Abstract 18907: Relationships Between Renal Haemodynamics With Cardiac and Aortic Haemodynamics in the Early Stages of Essential Hypertension

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Konstantinos Kintis ◽  
Costas Tsioufis ◽  
Anastasia Mazaraki ◽  
Evaggelia Koutra ◽  
Lefki Nikolopoulou ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Augmentation Index ◽  
Resistive Index ◽  
Renal Haemodynamics ◽  
Renal Resistive Index ◽  
Diabetic Patients ◽  
Diastolic Velocity ◽  
Relationship Of ◽  
The Relationship ◽  
Cardiac Haemodynamics

Introduction: The relationship of renal haemodynamics with cardiac and aortic hameodynamics is still unclear. Hypothesis: We evaluated the relationship of increased renal resistive index (RRI) with Augmentation index (AIx) and cardiac haemodynamics by means of mitral annular early diastolic velocity (E/Ea) in untreated patients with essential hypertension. Methods: 76 newly diagnosed untreated non diabetic patients with stage I-II essential hypertension [35 males, aged 50 years, office blood pressure (BP) = 143/ 91 mm Hg], underwent ABPM, complete echocardiographic study for determination of E/Ea and blood sampling for assessment of metabolic profile. Moreover, data on renal resistive index (RRI), obtained by Doppler ultrasound sampling of the intrarenal arteries, as well as augmentation index (AIx), were retrospectively analyzed. Results: Based on the mean value of RRI (0.60), hypertensives were classified into those with high and low RRI. Hypertensives with high RRI values compared to those with low values were older (55.6±9.8 vs 44.4±11.6 years, p < 0.001), had lower 24-hour diastolic BP (77.5±7.7 vs 84.3±6.7 mmHg, p < 0.001), lower 24-hour HR (71.2±10.3 vs 76.2±9.2 bpm, p < 0.05), higher levels of AIx (27.2±8.2 vs 17.8±14.8 %, p < 0.01), and higher values of E/Ea (lateral) (7.7±1.8 vs 6.2±2.3, p < 0.05). In the total population, RRI was negatively related to 24-hour diastolic BP (r = -0.523, p < 0.001) and 24-hour HR (r = -0.281, p < 0.05), while it was positively associated with CRP (r = 0.335, p < 0.05), TChol (r = 0.296, p < 0.01), age (r = 0.443, r < 0.001), AIx (r = 0.413, p = 0.001) and E/Ea(lateral) (r = 0.465, p < 0.05). Multiple regression analysis revealed that 24-hour diastolic BP and E/Ea (lateral) were independent associated with RRI (R2 = 0.434, p < 0.05). Conclusions: Increased vascular resistance of intrarenal arteries is associated with impaired aortic and cardiac haemodynamics, as reflected by increased AIx and E/Ea (lateral) values. RRI may be considered a useful surrogate of haemodynamics in essential hypertension.

Een beetje onsterfelijk

Lampas ◽  
2019 ◽  
Vol 52 (4) ◽  
pp. 437-452
Author(s):  
Gerard Boter
Keyword(s):  
Present Article ◽  
The Other ◽  
Relationship Of ◽  
The Relationship ◽  
Immortality Of The Soul

Summary The present article discusses three hotly debated interpretational issues in Diotima´s speech in Plato´s Symposium. The first of these is the relationship of Diotima´s speech to other dialogues, such as the Phaedo and the Republic, with regard to the immortality of the soul. It is argued that there is no discrepancy at all, because the immortality of the soul does not play any role in the Symposium. The second issue is the nature of the three classes of posterity: biological, spiritual and philosophical. Whereas the posterity of the first two classes can be relatively easily defined, the character of the philosopher´s posterity, ‘true virtue’, remains rather vague. It may consist in dialectical teaching of the Idea of Beauty by Socrates. Thirdly, it is argued that the philosopher´s immortality differs only gradually from the immortality of the other two classes, that is, the philosopher as a man only survives by means of his posterity.

Comparing the Arrangements of Governance and Sustainable Development in OECD Countries: Coupled or Decoupled?

2019 ◽  
Vol 34 (1) ◽  
pp. 99-117
Author(s):  
Huh Taewook
Keyword(s):  
Sustainable Development ◽  
Oecd Countries ◽  
The Other ◽  
Type Analysis ◽  
Ideal Types ◽  
Type 3 ◽  
Relationship Of ◽  
The Relationship

This study attempts to analyze to what extent governance and sustainable development (SD) empirically appear compatible in the thirtyfive OECD countries through the fuzzy-set ideal type analysis, and identify which ideal types appear coupled or decoupled, and then reveal which countries belong to the coupled types or to the decoupled types. In short, twenty-two countries (including Sweden (fuzzy score, 0.953), Denmark (0.920), Finland (0.914), Norway (0.911) in Type 1 (G*S, ‘strong G-S coupled countries’); and Turkey (0.906), Greece (0.833), Mexico (0.828) in Type 4 (g*s, ‘lite g-s coupled countries’) are in line with the accepted conventions regarding the compatible relationship between governance and SD. On the other hand, the rest of thirteen countries (including USA (fuzzy score, 0.815), Luxembourg (0.721), Australia (0.660) in Type 2 (G*s, ‘G-s decoupled countries’); and Slovenia (0.728), France (0.644), Czech Rep. (0.625) in Type 3 (g*S, ‘g-S decoupled countries’) may indicate that the relationship of governance and SD is in fact experiencing tensions in the national contexts. These findings are characterized by the substance (of SD) and procedure (of governance) divide. Considering the results, this study focuses on the idea of reflexivity or reflexive capacity.

Interpersonal Conflicts in the Relationship of Twins

1998 ◽  
Vol 47 (3-4) ◽  
pp. 153-160
Author(s):  
S. A. Gruszewska
Keyword(s):  
Social Life ◽  
Interpersonal Conflict ◽  
The Other ◽  
Psychological Space ◽  
Interpersonal Conflicts ◽  
Educational Methods ◽  
The Moment ◽  
Relationship Of ◽  
The Relationship

AbstractTaking into consideration two facts: that the structure of social life forces twins to part and that the presented roles in a pair are not equal, (one of the twins plays the role of a leader (L) and the other, the subordinate (P.)), one can ask the question — what meaning does the moment of parting have and what are its consequences?In order to do that, a survey was conducted, (a sample of 31 pairs of twins above the age of 30), in which every pair was asked the question: “Which one of you made the decision about parting?” The answer had two options: A – I, B – brother/sister. Out of 31 pairs of twins, 16 pairs chose the variant different from his brother or sister – that is A, B, admitting that the interpersonal conflict was the result of the parting. In 7 pairs, both twins chose the B variant – they withdrew from the conflict; and in 8 pairs they chose the A variant – looking for a compromise as the means of agreement.When analyzing the results of the survey, we can state the following:– in the relationship of twins, there is an interpersonal conflict;– the decision about parting is difficult with prevalent feelings of sadness and sorrow;– after parting, at least one of the twins has problems with preserving his identity and integrity of psychological space.Since the moment of parting is necessary and difficult, specialists and mainly parents are required to consciously change their position towards the relationship of twins. It has to be the result of applied educational methods which aim at creating subjectivity and equality of each of the twins before the moment of parting.

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