scholarly journals 1P235 Ligand screening of G protein-coupled receptors from a random peptide library

2005 ◽  
Vol 45 (supplement) ◽  
pp. S90
Author(s):  
Y. Sasaki ◽  
S. Takeda ◽  
K. Yamada ◽  
R. Katakai
Keyword(s):  
G Protein ◽  
Peptide Library ◽  
G Protein Coupled Receptors ◽  
Random Peptide Library ◽  
Random Peptide ◽  
Ligand Screening ◽  
G Protein Coupled

scholarly journals G protein-coupled receptors: structure- and function-based drug discovery

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Dehua Yang ◽  
Qingtong Zhou ◽  
Viktorija Labroska ◽  
Shanshan Qin ◽  
Sanaz Darbalaei ◽  
...  
Keyword(s):  
Drug Discovery ◽  
G Protein ◽  
Structure And Function ◽  
G Protein Coupled Receptors ◽  
Comprehensive Overview ◽  
Ligand Screening ◽  
Important Field ◽  
Common Interests ◽  
And Function ◽  
G Protein Coupled

AbstractAs one of the most successful therapeutic target families, G protein-coupled receptors (GPCRs) have experienced a transformation from random ligand screening to knowledge-driven drug design. We are eye-witnessing tremendous progresses made recently in the understanding of their structure–function relationships that facilitated drug development at an unprecedented pace. This article intends to provide a comprehensive overview of this important field to a broader readership that shares some common interests in drug discovery.

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