Ligand Screening of G Protein-Coupled Receptors in Yeast

2019 ◽  
pp. 49-70
Author(s):  
John R. Hadcock ◽  
Mark H. Pausch
Keyword(s):  
G Protein ◽  
G Protein Coupled Receptors ◽  
Ligand Screening ◽  
G Protein Coupled

scholarly journals G protein-coupled receptors: structure- and function-based drug discovery

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Dehua Yang ◽  
Qingtong Zhou ◽  
Viktorija Labroska ◽  
Shanshan Qin ◽  
Sanaz Darbalaei ◽  
...  
Keyword(s):  
Drug Discovery ◽  
G Protein ◽  
Structure And Function ◽  
G Protein Coupled Receptors ◽  
Comprehensive Overview ◽  
Ligand Screening ◽  
Important Field ◽  
Common Interests ◽  
And Function ◽  
G Protein Coupled

AbstractAs one of the most successful therapeutic target families, G protein-coupled receptors (GPCRs) have experienced a transformation from random ligand screening to knowledge-driven drug design. We are eye-witnessing tremendous progresses made recently in the understanding of their structure–function relationships that facilitated drug development at an unprecedented pace. This article intends to provide a comprehensive overview of this important field to a broader readership that shares some common interests in drug discovery.

Sign in / Sign up

Export Citation Format

Share Document