scholarly journals Review of Australian Health Economic Evaluation - 245 interventions: What Can We Say About Cost-Effectiveness?

2006 ◽  
Author(s):  
Kim Dalziel ◽  
Leonie Segal ◽  
Duncan Mortimer
Keyword(s):  
Health Economic ◽  
Economic Evaluation ◽  
Cost Effectiveness ◽  
Health Economic Evaluation ◽  
Australian Health

Quality of economic evaluations of ventricular assist devices: A systematic review

2020 ◽  
Vol 36 (4) ◽  
pp. 380-387
Author(s):  
Sarah Fontenay ◽  
Lionel Catarino ◽  
Soumeya Snoussi ◽  
Hélène van den Brink ◽  
Judith Pineau ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Economic ◽  
Economic Evaluation ◽  
Cost Effectiveness ◽  
Health Economic Evaluation ◽  
Ventricular Assist Devices ◽  
Economic Evaluations ◽  
Level Of Evidence ◽  
Ventricular Assist

ObjectiveBecause of a lack of suitable heart donors, alternatives to transplantation are required. These alternatives can have high costs. The aim of this study was to perform a systematic review of cost-effectiveness studies of ventricular assist devices (VADs) and to assess the level of evidence of relevant studies. The purpose was not to present economic findings.MethodsA systematic review was performed using four electronic databases to identify health economic evaluation studies dealing with VADs. The methodological quality and reporting quality of the studies was assessed using three different tools, the Drummond, Cooper, and CHEERS (Consolidated Health Economic Evaluation Reporting Standards) checklists.ResultsOf the 1,258 publications identified, thirteen articles were included in this review. Twelve studies were cost–utility analyses and one was a cost-effectiveness analysis. According to the Cooper hierarchy scale, the quality of the data used was heterogeneous. The level of evidence used for clinical effect sizes, safety data, and baseline clinical data was of poor quality. In contrast, cost data were of high quality in most studies. Quality of reporting varied between studies, with an average score of 17.4 (range 15–19) according to the CHEERS checklist.ConclusionThe current study shows that the quality of clinical data used in economic evaluations of VADs is rather poor in general. This is a concern that deserves greater attention in the process of health technology assessment of medical devices.

scholarly journals Complaint-Directed Mini-Interventions for Depressive Symptoms: A Health-Economic Evaluation of Unguided Web-Based Self-Help Interventions (Preprint)

2018 ◽  
Author(s):  
Ben F.M. Wijnen ◽  
Suzanne Lokman ◽  
Stephanie Leone ◽  
Silvia M.A.A. Evers ◽  
Filip Smit
Keyword(s):  
Health Economic ◽  
Economic Evaluation ◽  
Cost Effectiveness ◽  
Depressive Symptomatology ◽  
Health Economic Evaluation ◽  
Control Group ◽  
Web Based ◽  
Self Help ◽  
Low Threshold

BACKGROUND The past decades depression prevention and early intervention has become a top priority within the Netherlands, however, there is still considerable room for improvement. To this extent, web-based complaint-directed mini-interventions (CDMIs) were developed. These brief and low-threshold interventions focus on psychological stress, sleep problems, and worry, because these complaints are highly prevalent, are demonstrably associated with depression and have a substantial economic impact. OBJECTIVE Aim of the current economic evaluation is to examine the added value of web-based unguided self-help CDMIs as compared to a wait-listed control group with unrestricted access to usual care both from a societal and healthcare perspective. METHODS This health economic evaluation was embedded in a randomized controlled trial. The study entailed two-arms in which three web-based CMDIs were compared to a no-intervention waiting-list control group (control group received intervention at three months follow-up). Measurements were conducted at baseline, and at three- and six-months follow-up. Primary outcome of the study was response rate on depressive symptomatology as measured by the Inventory of Depressive Symptomatology Self-Report (IDS-SR). Change in quality of life was estimated by calculating effect sizes (Cohens’ d) for individual pre- and post-treatment IDS-SR scores. Incremental cost-effectiveness ratios (ICERs) were calculated using bootstraps (5000 times) of seemingly unrelated regression equations and cost-effectiveness acceptability curves were constructed for the costs per QALY gained. RESULTS In total, 329 participants were included in the study of which 165 randomized to the CDMI group. At three months follow-up the responder rate was 13.9% in the CDMI group and 7.3% in the control group. Participants in the CDMI group gained 0.15 QALY at three months follow-up compared to baseline, whereas participants in the control group gained 0.03 QALY at three months follow-up. Average total costs per patient during 3 months follow-up were €2,094 for the CDMI group and €2,230 for the control group (excluding baseline costs). Bootstrapped SURE models resulted in a dominant ICER (i.e. less costs and a higher responder rate) for the CDMI group compared to the control group at three months follow-up. The same result was found for the costs per QALY gained. Various sensitivity analyses attested to the robustness of the findings of the main analysis. CONCLUSIONS This study demonstrated that brief and low-threshold web-based unguided self-help CDMIs have the potential to be a cost-effective addition to usual care for adults with mild-to-moderate depressive symptoms. The CDMIs were shown to improve health status while at the same time reduced healthcare costs of participants and hence dominates the care as usual control condition. As intervention costs are relatively low, and Internet is nowadays readily available in the Western world, we believe the CDMIs can be easily implemented on a large scale. CLINICALTRIAL Netherlands Trial Register (NTR): NTR4612; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=4612 (Archived by WebCite at http://www.webcitation.org/6n4PVYddM)

Health economic evaluations: How to find them

2006 ◽  
Vol 22 (4) ◽  
pp. 512-517 ◽  
Author(s):  
Viveka Alton ◽  
Ingemar Eckerlund ◽  
Anders Norlund
Keyword(s):  
Health Economic ◽  
Economic Evaluation ◽  
Cost Effectiveness ◽  
Evaluation Studies ◽  
Health Economic Evaluation ◽  
Cost Effective ◽  
Cochrane Library ◽  
Bibliographic Databases ◽  
Economic Evaluations ◽  
Full Text Review

Objectives: The aim of this study was to demonstrate the best way of identifying all relevant published health economic evaluation studies, which have increased in number rapidly in the past few decades. Nevertheless, health technology assessment projects are often faced with a scarcity of relevant studies.Methods: Six bibliographic databases were searched using various individually adapted strategies. The particular example involves the cost-effectiveness of diagnosing gastroesophageal reflux disease. Inclusion and exclusion criteria were formulated.Results: After irrelevant studies and duplicates had been excluded, sixty-eight abstracts were reviewed. We chose forty-one of them as relevant for full-text review, which identified fourteen papers as having met the inclusion criteria. Most of the relevant studies were identified by searching the National Health Service Economic Evaluation Database (NHS EED) and PubMed databases.Conclusions: A search in NHS EED, by means of the Cochrane Library or the Center for Reviews and Dissimination, along with a supplementary search in PubMed, is generally an appropriate, cost-effective strategy. However, because “cost-effectiveness” is not consistently indexed with Medical Subject Heading terms in PubMed, all economic search terms need to be used to fully identify the relevant references.

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