Characterization of Host Response to a Polypropylene Mesh Implanted on the Vagina: Diabetic vs. Normoglycemic Conditions

2022 ◽  
Author(s):  
Rui Liang ◽  
Abigail Fisk ◽  
Gabrielle King ◽  
Leslie Meyn ◽  
Xiangwei Xiao ◽  
...  
Keyword(s):  
Polypropylene Mesh ◽  
Host Response

scholarly journals De-Coding the Contributions of the Viral RNAs to Alphaviral Pathogenesis

Pathogens ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 771
Author(s):  
Autumn T. LaPointe ◽  
Kevin J. Sokoloski
Keyword(s):  
Host Response ◽  
Severe Disease ◽  
Review Article ◽  
Structural Proteins ◽  
Virulence Determinants ◽  
Healthy Individuals ◽  
Viral Rnas ◽  
Positive Sense ◽  
Identification And Characterization

Alphaviruses are positive-sense RNA arboviruses that are capable of causing severe disease in otherwise healthy individuals. There are many aspects of viral infection that determine pathogenesis and major efforts regarding the identification and characterization of virulence determinants have largely focused on the roles of the nonstructural and structural proteins. Nonetheless, the viral RNAs of the alphaviruses themselves play important roles in regard to virulence and pathogenesis. In particular, many sequences and secondary structures within the viral RNAs play an important part in the development of disease and may be considered important determinants of virulence. In this review article, we summarize the known RNA-based virulence traits and host:RNA interactions that influence alphaviral pathogenesis for each of the viral RNA species produced during infection. Overall, the viral RNAs produced during infection are important contributors to alphaviral pathogenesis and more research is needed to fully understand how each RNA species impacts the host response to infection as well as the development of disease.

scholarly journals Characterization of and host response to tyramine substituted-hyaluronan enriched fascia extracellular matrix

2011 ◽  
Vol 22 (6) ◽  
pp. 1465-1477 ◽  
Author(s):  
LiKang Chin ◽  
Anthony Calabro ◽  
E. Rene Rodriguez ◽  
Carmela D. Tan ◽  
Esteban Walker ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Host Response

Characterization of host response to Cryptococcus neoformans through quantitative proteomic analysis of cryptococcal meningitis co-infected with HIV

2015 ◽  
Vol 11 (9) ◽  
pp. 2529-2540 ◽  
Author(s):  
Lakshmi Dhevi N. Selvan ◽  
Sreelakshmi K. Sreenivasamurthy ◽  
Satwant Kumar ◽  
Soujanya D. Yelamanchi ◽  
Anil K. Madugundu ◽  
...  
Keyword(s):  
Cryptococcus Neoformans ◽  
Cryptococcal Meningitis ◽  
Proteomic Analysis ◽  
Host Response ◽  
Quantitative Proteomic Analysis ◽  
Brain Proteome ◽  
Proteome Profile

Brain proteome profile of cryptococcal meningitis co-infected with HIV.

scholarly journals Integrated characterization of SARS-CoV-2 genome, microbiome, antibiotic resistance and host response from single throat swabs

2020 ◽  
Author(s):  
Bo Lu ◽  
Yi Yan ◽  
Liting Dong ◽  
Lingling Han ◽  
Yawei Liu ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Severe Acute Respiratory Syndrome ◽  
Host Response ◽  
Comprehensive Analysis ◽  
Clinical Samples ◽  
Full Genome ◽  
Rna Seq ◽  
Sequencing Data ◽  
Genome Information

AbstractThe ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, poses a severe threat to humanity. Rapid and comprehensive analysis of both pathogen and host sequencing data is critical to track infection and inform therapies. In this study, we performed unbiased metatranscriptomic analysis of clinical samples from COVID-19 patients using a newly-developed RNA-seq library construction method (TRACE-seq), which utilizes tagmentation activity of Tn5 on RNA/DNA hybrids. This approach avoids the laborious and time-consuming steps in traditional RNA-seq procedure, and hence is fast, sensitive and convenient. We demonstrated that TRACE-seq allowed integrated characterization of full genome information of SARS-CoV-2, putative pathogens causing coinfection, antibiotic resistance and host response from single throat swabs. We believe that the integrated information will deepen our understanding of pathogenesis and improve diagnostic accuracy for infectious diseases.

Characterization of the T-Cell Response to Polypropylene Mesh in Women With Complications

2019 ◽  
Vol 74 (5) ◽  
pp. 274-275 ◽  
Author(s):  
Lauren Tennyson ◽  
Matthew Rytel ◽  
Stacy Palcsey ◽  
Leslie Meyn ◽  
Rui Liang ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Response ◽  
Polypropylene Mesh ◽  
T Cell Response

Collagen-Chitosan- Glycerol-HPMC Composite as Cornea Artificial Candidate

2019 ◽  
Vol 42 ◽  
pp. 14-21
Author(s):  
Prihartini Widiyanti ◽  
Reni Prastyani
Keyword(s):  
Pore Size ◽  
Host Response ◽  
Living Cells ◽  
Cytotoxicity Test ◽  
Artificial Cornea ◽  
Functional Cluster ◽  
Post Surgery ◽  
Cornea Transplantation ◽  
Simplex Virus

The number of blindness is tend to be increased year by year. One of the blindness cause is cornea ulcer.The cause of cornea ulcer is bacteria, fungi, and herpes simplex virus. Cornea transplantation is the only treatment which could widely accepted for blindness. Transplant by donor network becomes the only treatment that is acceptable on a large for blindness. However, treatment donor transplants have many shortcomings in complications post surgery such as host response, donor limitations, incompatibility and the length of time healing. As technology develops, there are many corneal substitutes based on natural ingredients derived from collagen or their derivatives because they promise better properties in biocompatibility. The aim of research are to conduct the synthesis and characterization of collagen- chitosan- glycerol - HPMC as artificial cornea such functional cluster test, cytotoxycity test, morphological test and antibacterial test. Based on functional cluster test, there are functional groups of all components of composite materials. While from cytotoxicity test, all samples have a percentage of living cells above 85%. The morphology test is showed that the pore size of sample B with composition collagen-chitosan-glycerol-HPMC is in accordance with the standard pore size for keratoprothesis. Sample A (collagen-chitosan-glycerol) and sample B (collagen-chitosan-glycerol-HPMC) have strong antibacterial properties.Biocomposite of collagen-chitosan-glycerol could be considered as artificial cornea due to the proximity with the corneal characteristics.

Proteomic characterization of host response to Yersinia pestis and near neighbors

2004 ◽  
Vol 320 (2) ◽  
pp. 474-479 ◽  
Author(s):  
Brett A Chromy ◽  
Julie Perkins ◽  
Jenny L Heidbrink ◽  
Arlene D Gonzales ◽  
Gloria A Murphy ◽  
...  
Keyword(s):  
Yersinia Pestis ◽  
Host Response

scholarly journals Characterization of the plasma proteome of nonhuman primates during Ebola virus disease or melioidosis: a host response comparison

2019 ◽  
Vol 16 (1) ◽  
Author(s):  
Michael D. Ward ◽  
Ernst E. Brueggemann ◽  
Tara Kenny ◽  
Raven E. Reitstetter ◽  
Christopher R. Mahone ◽  
...  
Keyword(s):  
Host Response ◽  
Nonhuman Primates ◽  
Ebola Virus ◽  
Virus Disease ◽  
Ebola Virus Disease ◽  
Plasma Proteome

scholarly journals Multiple Channel Bridges for Spinal Cord Injury: Cellular Characterization of Host Response

2009 ◽  
Vol 15 (11) ◽  
pp. 3283-3295 ◽  
Author(s):  
Yang Yang ◽  
Laura De Laporte ◽  
Marina L. Zelivyanskaya ◽  
Kevin J. Whittlesey ◽  
Aileen J. Anderson ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Host Response ◽  
Multiple Channel ◽  
Cord Injury
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