Incidence of SARS-CoV-2 Infection and Related Mortality by Education Level During Three Phases of the 2020 Pandemic: A Population-Based Cohort Study in Rome

2021 ◽  
Author(s):  
Laura Angelici ◽  
Chiara Sorge ◽  
Mirko Di Martino ◽  
Giovanna Cappai ◽  
Massimo Stafoggia ◽  
...  
Keyword(s):  
Cohort Study ◽  
Population Based ◽  
Education Level ◽  
Related Mortality ◽  
Three Phases

scholarly journals Implications of parental lifestyle changes and education level on adolescent offspring weight: a population based cohort study - The HUNT Study, Norway

BMJ Open ◽  
2018 ◽  
Vol 8 (8) ◽  
pp. e023406 ◽  
Author(s):  
Marit Naess ◽  
Erik R Sund ◽  
Turid Lingaas Holmen ◽  
Kirsti Kvaløy
Keyword(s):  
Physical Activity ◽  
Cohort Study ◽  
Parental Education ◽  
Population Based ◽  
Education Level ◽  
Lifestyle Changes ◽  
Education Levels ◽  
Reduced Physical Activity ◽  
Z Scores ◽  
Over Time

ObjectiveObesity tends to cluster in families reflecting both common genetics and shared lifestyle patterns within the family environment. The aim of this study was to examine whether parental lifestyle changes over time, exemplified by changes in weight and physical activity, could affect offspring weight in adolescents and if parental education level influenced the relationship.Design, setting and participantsThe population-based cohort study included 4424 parent-offspring participants from the Nord-Trøndelag Health Study, Norway. Exposition was parental change in weight and physical activity over 11 years, and outcome was offspring weight measured in z-scores of body mass index (BMI) in mixed linear models.ResultsMaternal weight reduction by 2–6 kg was significantly associated with lower offspring BMI z-scores: −0.132 (95% CI −0.259 to −0.004) in the model adjusted for education. Parental weight change displayed similar effect patterns on offspring weight regardless of parents’ education level. Further, BMI was consistently lower in families of high education compared with low education in the fully adjusted models. In mothers, reduced physical activity level over time was associated with higher BMI z-scores in offspring: 0.159 (95% CI 0.030 to 0.288). Associations between physical activity change and adolescent BMI was not moderated by parental education levels.ConclusionLifestyle changes in mothers were associated with offspring BMI; reduced weight with lower—and reduced physical activity with higher BMI. Father’s lifestyle changes, however, did not significantly affect adolescent offspring’s weight. Overall, patterns of association between parental changes and offspring’s BMI were independent of parental education levels, though adolescents with parents with high education had lower weight in general.

scholarly journals Body-mass index and long-term risk of sepsis-related mortality: a population-based cohort study of 0.5 million Chinese adults

Critical Care ◽  
2020 ◽  
Vol 24 (1) ◽  
Author(s):  
Li Weng ◽  
Junning Fan ◽  
Canqing Yu ◽  
Yu Guo ◽  
Zheng Bian ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Body Mass ◽  
Population Based ◽  
Chinese Adults ◽  
Related Mortality

scholarly journals Prehemodialysis arteriovenous access creation is associated with better cardiovascular outcomes in patients receiving hemodialysis: a population-based cohort study

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e6680
Author(s):  
Cheng-Chieh Yen ◽  
Mei-Yin Liu ◽  
Po-Wei Chen ◽  
Peir-Haur Hung ◽  
Tse-Hsuan Su ◽  
...  
Keyword(s):  
Cohort Study ◽  
Population Based ◽  
Sensitivity Analyses ◽  
Major Adverse Cardiovascular Events ◽  
First Year ◽  
Research Database ◽  
All Cause Mortality ◽  
Arteriovenous Access ◽  
Stage Renal Disease ◽  
Related Mortality

Background Cardiovascular (CV) disease contributes to nearly half of the mortalities in patients with end-stage renal disease. Patients who received prehemodialysis arteriovenous access (pre-HD AVA) creation had divergent CV outcomes. Methods We conducted a population-based cohort study by recruiting incident patients receiving HD from 2001 to 2012 from the Taiwan National Health Insurance Research Database. Patients’ characteristics, comorbidities, and medicines were analyzed. The primary outcome of interest was major adverse cardiovascular events (MACEs), defined as hospitalization due to acute myocardial infarction, stroke, or congestive heart failure (CHF) occurring within the first year of HD. Secondary outcomes included MACE-related mortality and all-cause mortality in the same follow-up period. Results The patients in the pre-HD AVA group were younger, had a lower burden of underlying diseases, were more likely to use erythropoiesis-stimulating agents but less likely to use renin–angiotensin–aldosterone system blockers. The patients with pre-HD AVA creation had a marginally lower rate of MACEs but a significant 35% lower rate of CHF hospitalization than those without creation (adjusted hazard ratio (HR) 0.65, 95% confidence interval (CI) [0.48–0.88]). In addition, the pre-HD AVA group exhibited an insignificantly lower rate of MACE-related mortality but a significantly 52% lower rate of all-cause mortality than the non-pre-HD AVA group (adjusted HR 0.48, 95% CI [0.39–0.59]). Sensitivity analyses obtained consistent results. Conclusions Pre-HD AVA creation is associated with a lower rate of CHF hospitalization and overall death in the first year of dialysis.

scholarly journals Cancer‐related mortality among people with intellectual disabilities: A nationwide population‐based cohort study

Cancer ◽  
2021 ◽  
Author(s):  
Maarten Cuypers ◽  
Bianca W. M. Schalk ◽  
Anne J. N. Boonman ◽  
Jenneken Naaldenberg ◽  
Geraline L. Leusink
Keyword(s):  
Cohort Study ◽  
Intellectual Disabilities ◽  
Population Based ◽  
People With Intellectual Disabilities ◽  
Related Mortality

scholarly journals Associations between Physical Activity in Old Age and Dementia-Related Mortality: A Population-Based Cohort Study

2014 ◽  
Vol 4 (3) ◽  
pp. 410-418 ◽  
Author(s):  
Tor Atle Rosness ◽  
Bj�rn Heine Strand ◽  
Astrid Liv Mina Bergem ◽  
Knut Engedal ◽  
Espen Bjertness
Keyword(s):  
Physical Activity ◽  
Cohort Study ◽  
Old Age ◽  
Population Based ◽  
Related Mortality

scholarly journals Hepatitis C virus (HCV) infection and liver-related mortality: a population-based cohort study in southern Italy

2000 ◽  
Vol 29 (5) ◽  
pp. 922-927 ◽  
Author(s):  
Alberto R Osella ◽  
Giovanni Misciagna ◽  
Vito M Guerra ◽  
Marisa Chiloiro ◽  
Renato Cuppone ◽  
...  
Keyword(s):  
Cohort Study ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Southern Italy ◽  
Population Based ◽  
Hcv Infection ◽  
Related Mortality

scholarly journals COVID19-related and all-cause mortality risk among middle-aged and older adults across the first epidemic wave of SARS-COV-2 infection: a population-based cohort study in Southern Catalonia, Spain, March–June 2020

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Angel Vila-Corcoles ◽  
Eva Satue-Gracia ◽  
Angel Vila-Rovira ◽  
Cinta de Diego-Cabanes ◽  
Maria Jose Forcadell-Peris ◽  
...  
Keyword(s):  
Older Adults ◽  
Cohort Study ◽  
Nursing Home ◽  
Population Based ◽  
Considerable Proportion ◽  
Middle Aged ◽  
Mortality Risks ◽  
Increased Risk ◽  
All Cause Mortality ◽  
Related Mortality

Abstract Background Direct and indirect COVID19-related mortality is uncertain. This study investigated all-cause and COVID19-related deaths among middle-aged and older adults during the first wave of COVID-19 pandemic period, assessing mortality risks by pre-existing socio-demographic and medical underlying conditions. Methods Population-based cohort study involving 79,083 individuals ≥50 years-old in Tarragona (Southern Catalonia, Spain). Baseline cohort characteristics (age/sex, comorbidities and medications/vaccinations history) were established at study start (01/03/2020) and main outcomes were COVID19-related deaths (those occurred among patients with laboratory-confirmed COVID19) and all-cause deaths occurred among cohort members between 01/03/2020–30/06/2020. Mortality risks were assessed by Cox regression analyses. Results Cohort members were followed for 1,356,358 persons-weeks, occurring 576 all-cause deaths (124 COVID19-related deaths). Of the 124 deceased patients with a laboratory-confirmed COVID19, 112 (90.3%) died by (due to) COVID-19, while 12 (9.7%) died with COVID-19 (but likely due to other concomitant causes). All-cause mortality rate among cohort members across study period was 42.5 deaths per 100,000 persons-week, being 22.8 among healthy/unrelated-COVID19 subjects, 236.4 in COVID19-excluded/PCR-negative subjects, 493.7 in COVID19-compatible/PCR-unperformed subjects and 4009.1 in COVID19-confirmed patients. Increasing age, sex male, nursing-home residence, cancer, neurologic, cardiac or liver disease, receiving diuretics, systemic corticosteroids, proton-pump inhibitors and benzodiazepines were associated with increased risk of all-cause mortality; conversely, receiving renin-angiotensin inhibitors and statins were associated with reduced risk. Age/years (hazard ratio [HR]: 1.08; 95% confidence interval [CI]: 1.06–1.10), sex male (HR: 1.82; 95% CI: 1.24–2.70), nursing-home residence (HR: 12.56; 95% CI: 8.07–19.54) and number of pre-existing comorbidities (HR: 1.14; 95% CI: 1.01–1.29) were significant predictors for COVID19-related mortality, but none specific comorbidity emerged significantly associated with an increased risk in multivariable analysis evaluating it. Conclusion COVID19-related deaths represented more than 20 % of all-cause mortality occurred among middle-aged and older adults during the first wave of the pandemic in the region. A considerable proportion (around 10 %) of these COVID19-related deaths could be attributed to other concomitant causes. Theoretically COVID19-excluded subjects (PCR-negative) suffered ten-times greater all-cause mortality than healthy/unrelated-COVID19 subjects, which points to the existence of considerable number of false negative results in earlier PCR testing and could explain part of the global excess all-cause mortality observed during the pandemic.

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