A Novel Non-Enzyme Glucose  Biosensor Based on Bimetallic Pt-Au Nanoparticles Decorated Chinese Acupuncture Needle Microelectrode

2021 ◽  
Author(s):  
Qi Xiao ◽  
Guangxian Liu ◽  
Jiandan Chen ◽  
Chunchuan Gu ◽  
Zhengzhi Yin ◽  
...  
Keyword(s):  
Au Nanoparticles ◽  
Glucose Biosensor ◽  
Acupuncture Needle ◽  
Chinese Acupuncture

scholarly journals Novel amperometric glucose biosensor based on MXene nanocomposite

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
R. B. Rakhi ◽  
Pranati Nayak ◽  
Chuan Xia ◽  
Husam N. Alshareef
Keyword(s):  
Au Nanoparticles ◽  
Synergistic Effects ◽  
High Sensitivity ◽  
Glucose Biosensor ◽  
Glucose Detection ◽  
Carbon Electrode ◽  
Potential Candidate ◽  
Amperometric Response ◽  
Excellent Stability ◽  
Electrochemical Transducer

Abstract A biosensor platform based on Au/MXene nanocomposite for sensitive enzymatic glucose detection is reported. The biosensor leverages the unique electrocatalytic properties and synergistic effects between Au nanoparticles and MXene sheets. An amperometric glucose biosensor is fabricated by the immobilization of glucose oxidase (GOx) enzyme on Nafion solubilized Au/ MXene nanocomposite over glassy carbon electrode (GCE). The biomediated Au nanoparticles play a significant role in facilitating the electron exchange between the electroactive center of GOx and the electrode. The GOx/Au/MXene/Nafion/GCE biosensor electrode displayed a linear amperometric response in the glucose concentration range from 0.1 to 18 mM with a relatively high sensitivity of 4.2 μAmM−1 cm−2 and a detection limit of 5.9 μM (S/N = 3). Furthermore, the biosensor exhibited excellent stability, reproducibility and repeatability. Therefore, the Au/MXene nanocomposite reported in this work is a potential candidate as an electrochemical transducer in electrochemical biosensors.

Glucose biosensor based on Au nanoparticles–conductive polyaniline nanocomposite

2006 ◽  
Vol 21 (10) ◽  
pp. 1996-2000 ◽  
Author(s):  
Yuezhong Xian ◽  
Yi Hu ◽  
Fang Liu ◽  
Yang Xian ◽  
Haiting Wang ◽  
...  
Keyword(s):  
Au Nanoparticles ◽  
Glucose Biosensor ◽  
Conductive Polyaniline ◽  
Polyaniline Nanocomposite

scholarly journals Investigating the Effects of Three Needling Parameters (Manipulation, Retention Time, and Insertion Site) on Needling Sensation and Pain Profiles: A Study of Eight Deep Needling Interventions

2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Bertrand Y. K. Loyeung ◽  
Deirdre M. Cobbin
Keyword(s):  
Retention Time ◽  
Healthy Subjects ◽  
Insertion Site ◽  
Needle Insertion ◽  
Manual Acupuncture ◽  
Post Intervention ◽  
Acupuncture Needle ◽  
Chinese Acupuncture ◽  
Pain Scores ◽  
Subsequent Measurement

Introduction. In traditional Chinese acupuncture, needle sensation (deqi) is purported to contribute to a therapeutic outcome. While researchers have attempted to definedeqiqualitatively, few have examined the effects of needling parameters on its intensity.Methods. 24 healthy subjects completed eight interventions scheduled at least one week apart, which involved manual acupuncture to LI4 or a designated nonacupoint (NAP) on the hand, with real or simulated manipulation each three minutes and needle retentions of one or 21 minutes. Intensities of needling sensation and pain were reported every three minutes and sensation qualities were reported post-intervention.Results. Immediately after needle insertion, similar levels of mean needle sensation and of pain were reported independent of intervention. At subsequent measurement times, only two interventions (one at LI4 and one at NAP) maintained statistically significantly elevated needle sensation and pain scores and reported higher numbers of needle sensation descriptors. For both, the needle was retained for 21 minutes and manipulated every three minutes. Neither intervention differed significantly in terms of levels of pain, and needle sensation or numbers and qualities of needle sensation described.Conclusion. In this group of healthy subjects, the initial needling for all eight interventions elicited similar levels of needle sensation and pain. These levels were only maintained if there was ongoing of needle manipulation and retention of the needle. By contrast, the strength of needle sensation or pain experienced was independent of insertion site.

A super highly sensitive glucose biosensor based on Au nanoparticles–AgCl@polyaniline hybrid material

2008 ◽  
Vol 23 (7) ◽  
pp. 925-931 ◽  
Author(s):  
Wei Yan ◽  
Xiaomiao Feng ◽  
Xiaojun Chen ◽  
Wenhua Hou ◽  
Jun-Jie Zhu
Keyword(s):  
Hybrid Material ◽  
Au Nanoparticles ◽  
Glucose Biosensor ◽  
Highly Sensitive

Radiolytic Synthesis of Pt-M@MWNT Catalysts (M=Ru, Sn, and Au) for Biosensors

2013 ◽  
Vol 717 ◽  
pp. 139-145
Author(s):  
Hai Doo Kwen ◽  
Seong Ho Choi
Keyword(s):  
Au Nanoparticles ◽  
Glucose Biosensor ◽  
Food Chemistry ◽  
X Ray Diffraction ◽  
X Ray ◽  
Electrochemical Testing ◽  
Multi Walled Carbon Nanotube ◽  
Enzymatic Biosensors ◽  
Alloy Properties ◽  
Radiolytic Synthesis

Non-enzymatic biosensors employing multi-walled carbon nanotube (MWNT) with highly dispersed Pt-M (M = Ru, Sn, and Au) nanoparticles (Pt-M@MWNT catalysts) were fabricated by radiolytic deposition. The Pt-M nanoparticles on the MWNTs were characterized by transmittance electron microscopy, elemental analysis, and X-ray diffraction. They were found to be well-dispersed and to exhibit alloy properties on the MWNT support. Electrochemical testing showed that these non-enzymatic biosensors had larger currents (mA) than that of a bare glassy carbon (GC) electrode and one modified with MWNTs. The sensitivity (μA mM-1), linear range (mM), and detection limit (mM) (S/N = 3) of the glucose biosensor with the Pt-Ru, Pt-Sn and Pt-Au catalysts in PBS electrolyte were determined, respectively. The experimental results show that such biosensors can be applied to glucose detection in food chemistry field.

Application of Au Nanoparticles–AgCl@Polypyrrole Hybrid Material to Amperometric Biosensor

2010 ◽  
Vol 92 ◽  
pp. 23-28 ◽  
Author(s):  
Xiang Zhong Ren ◽  
Li Zhang ◽  
Ying Kai Jiang ◽  
Pei Xin Zhang ◽  
Jian Hong Liu ◽  
...  
Keyword(s):  
Hybrid Material ◽  
Sodium Citrate ◽  
Au Nanoparticles ◽  
Chemical Oxidation ◽  
Glucose Biosensor ◽  
In Situ Chemical Oxidation ◽  
Highly Sensitive ◽  
Chemical Oxidation Polymerization ◽  
Infrared Spectrometer

AgCl@polypyrrole(PPy) nanocomposites were synthesized through in situ chemical oxidation polymerization by using poly(vinylpyrrolidane) (PVP) as dispersant, and some Au colloid were prepared by using KBH4 as reductant and sodium citrate as stabilizer, then the Au nanoparticles-AgCl@PPy hybrid material was formed by physical chemical reaction. Fourier transform infrared spectrometer (FTIR) and electron dispersive spectrometer (EDS) data suggested that the hybrid material were composed of Au, AgCl and PPy. An amperometric glucose biosensor was fabricated by adsorbing glucose oxidase (GOx) to an Au nanoparticles-AgCl@PPy hybrid material modified platinum electrode. The biosensor exhibited a super highly sensitive response to H2O2.

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