Novel Biodegradable PTX-PLGA-Coated Magnesium Stent for Benign Esophageal Stricture: An Experimental Study

2021 ◽  
Author(s):  
Lin-Lin Liu ◽  
Juan Qin ◽  
Chu-Hui Zeng ◽  
Rui-Jie Du ◽  
Tao Pan ◽  
...  
Keyword(s):  
Experimental Study ◽  
Esophageal Stricture ◽  
Benign Esophageal Stricture

Tu1613 Characterization of Swine Models of Benign Esophageal Stricture for the Evaluation of Esophageal Stents.

2015 ◽  
Vol 81 (5) ◽  
pp. AB529-AB530
Author(s):  
Moises A. Rivera Bermudez ◽  
Lynne Swanson ◽  
Amy Townsend ◽  
Sharon E. Hunter ◽  
Jennifer K. Saunders ◽  
...  
Keyword(s):  
Esophageal Stricture ◽  
Benign Esophageal Stricture ◽  
Esophageal Stents

PS01.095: BENIGN ESOPHAGEAL STRICTURE: A RECAP OF OUR EXPERIENCE

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 76-76
Author(s):  
Keat How Teoh ◽  
Kelvin Voon ◽  
Shyang Yee Lim ◽  
Premnath Nagalingam
Keyword(s):  
Endoscopic Treatment ◽  
Esophageal Stricture ◽  
Endoscopic Dilatation ◽  
Line Treatment ◽  
First Line ◽  
Benign Esophageal Stricture ◽  
Anastomotic Strictures ◽  
Esophageal Strictures ◽  
The Mean ◽  
First Line Treatment

Abstract Background Caustic injury remains the commonest cause of benign esophageal strictures in Asia. Others include gastroesophageal reflux, iatrogenic, radiation, autoimmune or idiopathic causes. Treatment goals are relief of dysphagia and prevention of recurrence. This study aims to evaluate the experience with benign esophageal stricture in Penang Hospital, a tertiary hospital in Northern region of Malaysia. Methods A retrospective review of 12 patients with benign esophageal strictures between year 2012 - 2017. Results The mean age was 53.5 and two thirds were female. Half of these patients were of Chinese ethnicity while the other half were Indian. The commonest cause was caustic ingestion (41.7%), followed by reflux stricture (25%) and anastomotic stricture (25%). There was one case of dystrophic epidermolysis bullosa. More than half of the patients had complex and multiple strictures. 41.7% of patients had proximal strictures that were located within 20cm from the incisors. Endoscopic dilatation was the first line treatment with either Savary Gilliard or balloon dilators. A total of 97 dilatation sessions were done with a mean dilatation frequency of 2.3 ± 1.5 times for anastomotic strictures, 8 ± 8.2 times for reflux strictures and 8.0 ± 6.6 times for corrosive strictures. The mean dilatation interval was 2.5 ± 1.2 weeks. 58.3% of patients had successful endoscopic treatment. The success rate was higher in non-corrosive stricture (83% vs 40%). There was one dilatation related complication in which the patient had pneumomediastinum without overt mediastinitis. This however, resolved with conservative management. 41.7% of patients had refractory strictures that failed endoscopic dilatation. Surgery including esophagectomy (40%), revision of anastomosis (20%) and gastrostomy (40%) were done for this group of patients. Proximal strictures, complex strictures and multiple strictures were associated with failed endoscopic dilatation (P < 0.05). Conclusion Endoscopic dilatation is the first line treatment for benign esophageal strictures. Surgery is reserved for refractory strictures with failed endoscopic treatment. Predictor scoring systems for refractory stricture and individualized approaches are the key to success. Disclosure All authors have declared no conflicts of interest.

Treatment of Esophageal Stricture Complicated by Sudden Death

1973 ◽  
Vol 82 (6) ◽  
pp. 805-808
Author(s):  
John T. Howard
Keyword(s):  
Cardiovascular Disease ◽  
Hiatal Hernia ◽  
Esophageal Stricture ◽  
Fibrous Tissue ◽  
Lower Lobe ◽  
Esophageal Wall ◽  
Benign Esophageal Stricture ◽  
Lower Esophagus ◽  
Benign Stricture ◽  
The Right

An elderly lady with arteriosclerotic cardiovascular disease had had dysphagia intermittently for five years before she came under treatment for a benign esophageal stricture which was associated with an hiatal hernia. When her condition became refractory to bouginage and to the passage of beads over a previously swallowed thread, an attempt was made “to soften” the hard fibrous stricture by injecting triamcinolone mixed with hyaluronidase into it. The obstructing fibrous tissue was not softened immediately after the injection of these drugs. Four days later, with the hope that the steroid had “softened” the fibrous stricture, the patient swallowed a thread preliminary to the passage of dilating beads over it. She retired with the thread in place. During the night she was heard to cough and she was found to be dead five minutes later. At necropsy an hiatal hernia with a benign stricture of the lower esophagus was found. Needle tracts were seen in the stricture and deposits of injected material could be seen in the tissues; one tract went through the esophageal wall and there was minor mediastinitis with abscess formation. However, when the stomach and esophagus were distended with a solution of formalin under pressure, no leak could be found. A small thromboembolus in the lower lobe of the right lung might have caused the patient's death.

Mo1232 NEW STRATEGIES FOR PREVENTION OF ESOPHAGEAL STRICTURE AFTER CIRCUMFERENTIAL ENDOSCOPIC DISSECTION - AN EXPERIMENTAL STUDY

2019 ◽  
Vol 89 (6) ◽  
pp. AB476-AB477
Author(s):  
Radek Dolezel ◽  
Bara Walterova ◽  
Zuzana Vackova ◽  
Stefan Juhas ◽  
Jana Juhasova ◽  
...  
Keyword(s):  
Experimental Study ◽  
Esophageal Stricture ◽  
New Strategies
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