Severe COVID-19 in People with Type 1 and Type 2 Diabetes in Sweden: A Nationwide Retrospective Case-Control Study

2021 ◽  
Author(s):  
Aidin Rawshani ◽  
Elin Allansson Kjölhede ◽  
Araz Rawshani ◽  
Naveed Sattar ◽  
Katarina Eeg-Olofsson ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Case Control Study ◽  
Case Control ◽  
Retrospective Case ◽  
Control Study

scholarly journals Differences in risk factors of malignancy between men and women with type 2 diabetes: A retrospective case-control study

Oncotarget ◽  
2017 ◽  
Vol 8 (40) ◽  
pp. 66940-66950 ◽  
Author(s):  
Mariusz Dąbrowski ◽  
Elektra Szymańska-Garbacz ◽  
Zofia Miszczyszyn ◽  
Tadeusz Dereziński ◽  
Leszek Czupryniak
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Case Control Study ◽  
Case Control ◽  
Retrospective Case ◽  
Men And Women ◽  
Control Study

scholarly journals Association of Higher Circulating Insulin Antibody with Increased Mean Amplitude Glycemic Excursion in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional, Retrospective Case-Control Study

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Jian Zhu ◽  
Lu Yuan ◽  
Wen-ji Ni ◽  
Yong Luo ◽  
Jian-hua Ma
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Case Control Study ◽  
Mean Amplitude ◽  
Case Control ◽  
Retrospective Case ◽  
Cross Sectional ◽  
The Relationship ◽  
Control Study

Insulin antibody (IA) may potentially affect a patient’s glycemic control due to its variability in both binding and/or releasing insulin. However, the association between IA titer and daily glycemic variability (GV) is still unknown. We thus performed this cross-sectional, retrospective case-control study to assess the relationship between IA titer and mean amplitude glycemic excursion (MAGE) in type 2 diabetes mellitus (T2DM) patients using a continuous glucose monitoring (CGM) system. We recruited 100 eligible patients (IA>5%, IA positive) and divided them into two groups—a low (L) group and a high (H) group—based on their IA titer. The control (C) group consisted of 47 patients (IA≤5%, IA negative) matched for age, BMI, gender, and glycosylated hemoglobin A1c (HbA1c). The CGM determined the GV of enrolled patients. The primary outcome was the relationship between the IA titer and the MAGE, and the secondary outcome was the differences of GV among the three groups. We found that patients in the H group had higher levels of blood glucose fluctuation parameters than those in the L and C groups. The Ln(IA) was positively correlated with Ln(MAGE) even after adjusting for age, gender, BMI, HbA1c, and fasting and postprandial C-peptide(r=0.423, p<0.001). Multiple linear stepwise regression analysis revealed that Ln(IA) was an independent factor of Ln(MAGE) (beta=0.405, p<0.001). In conclusion, the higher circulating IA titer was associated with increased MAGE in T2DM patients, indicating that those patients with elevated IA titer should receive GV assessment and individualized treatment.

scholarly journals The Association of Arsenic Exposure and Metabolism With Type 1 and Type 2 Diabetes in Youth: The SEARCH Case-Control Study

Diabetes Care ◽  
2016 ◽  
Vol 40 (1) ◽  
pp. 46-53 ◽  
Author(s):  
Maria Grau-Pérez ◽  
Chin-Chi Kuo ◽  
Miranda Spratlen ◽  
Kristina A. Thayer ◽  
Michelle A. Mendez ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Case Control Study ◽  
Arsenic Exposure ◽  
Case Control ◽  
Control Study ◽  
Diabetes In Youth

scholarly journals HbA 1C variability and hypoglycemia hospitalization in adults with type 1 and type 2 diabetes: A nested case-control study

2018 ◽  
Vol 32 (2) ◽  
pp. 203-209 ◽  
Author(s):  
Victor W. Zhong ◽  
Juhaeri Juhaeri ◽  
Stephen R. Cole ◽  
Christina M. Shay ◽  
Penny Gordon-Larsen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Case Control Study ◽  
Case Control ◽  
Nested Case Control ◽  
Control Study

Alexithymia impact on type 1 and type 2 diabetes: A case-control study

2014 ◽  
Vol 75 (4) ◽  
pp. 213-219 ◽  
Author(s):  
Leila Mnif ◽  
Rahma Damak ◽  
Fatma Mnif ◽  
Sami Ouanes ◽  
Mohamed Abid ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

Perinatal Risk Factors in Young Adult-Onset Type 1 and Type 2 Diabetes—A Population-Based Case-Control Study

2009 ◽  
Vol 64 (8) ◽  
pp. 511-512
Author(s):  
Niina Lammi ◽  
Paul A. Blomstedt ◽  
Elena Moltchanova ◽  
Johan G. Eriksson ◽  
Jaakko Tuomilehto ◽  
...  
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Adult Onset ◽  
Perinatal Risk Factors ◽  
Control Study

scholarly journals Characteristics of the Gut Microbiota and Metabolism in Patients With Latent Autoimmune Diabetes in Adults: A Case-Control Study

2021 ◽  
Author(s):  
Yuanyuan Fang ◽  
Chenhong Zhang ◽  
Hongcai Shi ◽  
Wei Wei ◽  
Jing Shang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Type 1 Diabetes ◽  
Gut Microbiota ◽  
Case Control Study ◽  
Autoimmune Diabetes ◽  
Case Control ◽  
Latent Autoimmune Diabetes ◽  
Control Study

OBJECTIVE <p>Type 1 and type 2 diabetes are associated with gut dysbiosis. However, the relationship between the gut microbiota and latent autoimmune diabetes in adults (LADA), sharing clinical and metabolic features with classic type 1 and type 2 diabetes, remains unclear. Here, we identified the characteristics of the gut microbiota and metabolic profiles in patients with LADA using a multi-omics approach.</p> <p>RESEARCH DESIGN AND METHODS</p> <p>This age- and sex-matched case-control study included 30 patients with LADA, 31 patients with classic type 1 diabetes, 30 patients with type 2 diabetes, and 29 healthy individuals. The gut microbiota profiles were identified via the 16S rRNA gene, and fecal and serum metabolites were measured via untargeted liquid chromatography-mass spectrometry.</p> <p>RESULTS </p> <p>LADA patients had a significantly different structure and composition of the gut microbiota and their metabolites as well as a severe deficiency of short-chain fatty acid-producing bacteria. The gut microbiota structure of the LADA patients was more similar to that of patients with type 1 diabetes who were positive for GAD antibody. We identified seven serum metabolite modules and eight fecal metabolite modules that differed between the LADA group and the other groups.</p> <p>CONCLUSIONS </p> <p><a>The characteristic gut microbiota and related metabolites of patients with LADA are associated with autoantibodies, glucose metabolism, islet function, and inflammatory factors, which may contribute to the pathogenesis of LADA. </a>Future longitudinal studies should explore whether modulating the gut microbiota and related metabolites can alter the natural course of autoimmune diabetes, in the quest for new therapeutic.</p>

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