Therapeutic effects of traditional Chinese medicines in experimental autoimmune prostatitis mouse model

2020 ◽  
Author(s):  
XIngxing Cui ◽  
Muhammad Naveed ◽  
Mirza Muhammad Faran Ashraf Baig ◽  
Wenlu Wang ◽  
Reyaj Mikrani ◽  
...  
Keyword(s):  
Mouse Model ◽  
Therapeutic Effects ◽  
Traditional Chinese Medicines ◽  
Chinese Medicines ◽  
Experimental Autoimmune

scholarly journals Application of Traditional Chinese Medicines in Postoperative Abdominal Adhesion

2020 ◽  
Vol 2020 ◽  
pp. 1-9 ◽  
Author(s):  
Fuling Wu ◽  
Wenqin Liu ◽  
Haixing Feng ◽  
Li Long ◽  
Lianbing Hou ◽  
...  
Keyword(s):  
Acupuncture Treatment ◽  
Modern Medicine ◽  
Clinical Applications ◽  
Therapeutic Effects ◽  
Traditional Chinese Medicines ◽  
Chinese Medicinal Herbs ◽  
Active Components ◽  
Chinese Medicines ◽  
Abdominal Adhesion ◽  
New Strategies

Adhesion is a frequent complication after abdominal surgery. Although various methods have been applied to prevent and treat postoperative abdominal adhesion (PAA), few modern drugs designed for clinical applications have reached the expected preventive or therapeutic effect so far. There is an imperative to develop some new strategies for the treatment of PAA. Traditional Chinese medicine (TCM) has been widely practiced for thousands of years and played an indispensable role in the prevention and treatment of diseases. Modern medicine researchers have accepted the therapeutic effects of many active components derived from Chinese medicinal herbs. The review stresses the most commonly used TCM treatment, including Chinese medicinal herbals and monomers, TCM formulas, and acupuncture treatment.

The Neuroprotective Effects of BNG-1: A New Formulation of Traditional Chinese Medicines for Stroke

2005 ◽  
Vol 33 (01) ◽  
pp. 61-71 ◽  
Author(s):  
Fong-Chi Cheng ◽  
Wen-Long Chen ◽  
Jiann-Wu Wei ◽  
Ken-Shung Huang ◽  
George G. Yarbrough
Keyword(s):  
Clinical Results ◽  
Artery Occlusion ◽  
Drug Formulation ◽  
Cerebral Stroke ◽  
Therapeutic Effects ◽  
Traditional Chinese Medicines ◽  
Neuroprotective Effects ◽  
Chinese Medicines

BNG-1, a novel mixture of traditional Chinese medicines with a long history in the treatment of stroke, exhibited acute neuroprotection effect on rats with middle cerebral artery occlusion (MCAO). Anti-ischemic effects were seen in both animals receiving BNG-1 before the ischemic insult as well as in animals receiving the drug formulation after surgical occlusion of the artery. Anti-thrombic activity was seen in vitro to inhibit arachidonic acid-induced platelet aggregation and in vivo to prolong bleeding time in mice. BNG-1 was also found to inhibit several phosphodiesterase (PDE) isoforms with potency order of the following rank: PDE 1>PDE 3>PDE 6>PDE 2>PDE 4>PDE 5. Other pre-clinical results and emerging clinical data coupled with the present findings suggest that BNG-1 may be a safe and effective therapy for both the prevention and treatment of cerebral stroke. Moreover, the fundamental cellular mechanism underlying its therapeutic effects may result from phosphodiesterase inhibition.

scholarly journals A Comprehensive Review on Pharmacokinetic Profile of Some Traditional Chinese Medicines

2016 ◽  
Vol 2016 ◽  
pp. 1-31 ◽  
Author(s):  
Piyush Mehta ◽  
Vividha Dhapte
Keyword(s):  
Chemical Constituents ◽  
Herbal Medicines ◽  
Pharmacokinetic Profile ◽  
Pharmacokinetic Data ◽  
Therapeutic Effects ◽  
Traditional Chinese Medicines ◽  
Herbal Drug ◽  
Major Drawback ◽  
Chinese Medicines ◽  
Wide Range

Herbal medicines are the oldest and most widely used form of treatment for welfare of mankind. Herbal medicines possess strong reputation as complementary treatment across the globe due to their easy accessibility and safety. Particularly traditional Chinese medicines (TCM) are very popular due to their desirable therapeutic effects. They already have been proven for their remarkable potential in treatment of wide range of disease ailments. The major drawback in using herbal medicines is lack of standardisation aspects due to the complexity of chemical constituents. Pharmacokinetics study of such medicines helps forecast a range of events related to efficacy, safety, and toxicity profile of them. Apart from this, pharmacokinetics studies also recommended by various regulatory agencies during diverse stages of herbal drug development. Thus it is highly essential to have knowledge about the pharmacokinetic properties of any herbal drug. Thus it was thought that it will be worthwhile to compile the pharmacokinetic data of TCM which will be helpful for the researchers involved in further research on TCM. To portray entire picture about absorption, distribution, metabolism, and excretion (ADME) of some TCM, this well-designed scientific review covers the pharmacokinetic profile of 50 TCM available from 2003 and onwards.

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