Suppression of lncRNA Xist Improves Sevoflurane-Induced Social and Emotional Impairment by Activating miR-98-5p/EDEM1 Signaling Axis in Neonatal Mice

2020 ◽  
Author(s):  
Lili Xu ◽  
Qi Xu ◽  
Shaobing Dai ◽  
Wenxin Zhang ◽  
Hui Wu ◽  
...  
Keyword(s):  
Social And Emotional ◽  
Neonatal Mice ◽  
Signaling Axis ◽  
Lncrna Xist ◽  
Emotional Impairment

The Assessment of Emotional Awareness in Children

2011 ◽  
Vol 27 (4) ◽  
pp. 265-273 ◽  
Author(s):  
Elke Veirman ◽  
Symen A. Brouwers ◽  
Johnny R. J. Fontaine
Keyword(s):  
Emotional Intelligence ◽  
Construct Validity ◽  
Age Differences ◽  
Emotional Awareness ◽  
Future Research ◽  
Alternative Design ◽  
Social And Emotional ◽  
And Gender ◽  
Emotional Impairment ◽  
Validity Research

The Levels of Emotional Awareness Scale (LEAS) is a widely used scenario-based instrument that has been developed for the measurement of emotional awareness in adults. Although the LEAS has been validated in numerous studies, published validity research on the recently developed child version (LEAS-C) is scarce. The objective of the present study was to evaluate the construct validity of the Dutch LEAS-C in a sample of 318 children, aged 10 to 17 years. Outcomes revealed novel structural evidence in favor of alternative design-driven modeling. Further, the pattern of relationships with ability- and trait-oriented emotional intelligence, intelligence, personality, social and emotional impairment, and gender was generally consistent with previous theorizing and adult studies on the LEAS. Reasons for absence of age differences are discussed. In conclusion, this study corroborates the construct validity of the LEAS-C and highlights the importance of fully exploring the LEAS-C in its potential. Directions for future research are proposed.

Parent observed neuro-behavioral and pro-social improvements with oxytocin following surgical resection of craniopharyngioma

2016 ◽  
Vol 29 (8) ◽  
Author(s):  
Naomi Cook ◽  
Jennifer Miller ◽  
John Hart
Keyword(s):  
Quality Of Life ◽  
Surgical Resection ◽  
Low Dose ◽  
Individual Treatment ◽  
Social Emotional ◽  
Hypothalamic Dysfunction ◽  
Social And Emotional ◽  
Potential Benefits ◽  
Emotional Impairment

AbstractSocial and emotional impairment, school dysfunction, and neurobehavioral impairment are highly prevalent in survivors of childhood craniopharyngioma and negatively affect quality of life. As surgical resection of craniopharyngioma typically impairs hypothalamic/pituitary function, it has been postulated that perhaps post-operative deficiency of the hormone oxytocin may be the etiology of social/emotional impairment. Research on the benefits of oxytocin treatment as a hormone facilitating social interaction is well established. However, no research has yet been conducted on patients with known pituitary/hypothalamic dysfunction due to structural lesions or surgery. This case report investigates the effects of oxytocin therapy on a youngster with pituitary/hypothalamic dysfunction after craniopharyngioma removal. In this individual, treatment with low dose intranasal oxytocin resulted in increased desire for socialization and improvement in affection towards family. In light of these findings, the authors believe that further research into the potential benefits of intranasal oxytocin therapy for patients with panhypopituitarism is necessary to determine whether a broader population may also benefit from intranasal oxytocin therapy.

Social and Emotional Robots for Aging Well?

GeroPsych ◽  
2013 ◽  
Vol 26 (2) ◽  
pp. 81-82
Author(s):  
Barbara Klein ◽  
Monika Knopf ◽  
Frank Oswald ◽  
Johannes Pantel
Keyword(s):  
Social And Emotional ◽  
Aging Well

The Type D Construct

2014 ◽  
Vol 30 (4) ◽  
pp. 283-288 ◽  
Author(s):  
Gesine Grande ◽  
Matthias Romppel ◽  
Matthias Michal ◽  
Elmar Brähler
Keyword(s):  
Social Functioning ◽  
Negative Affectivity ◽  
Population Based ◽  
Type D Personality ◽  
Social Orientation ◽  
German Population ◽  
Social Competencies ◽  
Social And Emotional ◽  
Type D ◽  
Worse Prognosis

The interaction of negative affectivity (NA) and social inhibition (SI), known as the Type D personality, is associated with a worse prognosis in cardiac patients. Until now, causal models have been speculative, and this is partly due to a lack of clarity related to the validity of SI, its role in emotion regulation, and the postulated independence of social and emotional functioning. To examine the construct validity of the Type D personality, we analyzed associations of NA and SI with different measures of affectivity, social anxiety, and social competencies in a German population-based representative sample (n = 2,495). Both NA and SI were associated with all other measures of social functioning and negative affect (all rs > .30) and showed considerable cross-loadings (NA: a 1 = .39, a 2 = .63; SI: a1 = .73 and a2 = .34) in a two-factor solution with the factors labeled as Social Functioning and Negative Affectivity. The SI subscale did not properly differentiate between social fears and social competencies, which emerged as rather different aspects of social functioning. Further studies should examine the effect of broader dimensions of social orientation and competencies and their interaction with NA on cardiac prognosis.

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