Cell Membrane-Camouflaged Nanoparticles as Drug Carriers for Cancer Therapy

2019 ◽  
Author(s):  
Cheng-Hui Xu ◽  
Peng-Ju Ye ◽  
Yang-Chun Zhou ◽  
Dong-Xiu He ◽  
Cui-Yun Yu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Cell Membrane ◽  
Drug Carriers

Cell membrane-inspired polymeric micelles as carriers for drug delivery

2015 ◽  
Vol 3 (3) ◽  
pp. 490-499 ◽  
Author(s):  
Gongyan Liu ◽  
Quanqing Luo ◽  
Haiqi Gao ◽  
Yuan Chen ◽  
Xing Wei ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Cell Membrane ◽  
Polymeric Micelles ◽  
Drug Carriers

Cell membrane-inspired polymeric micelles were designed as drug carriers for cancer therapy.

Cell membrane-camouflaged nanoparticles as drug carriers for cancer therapy

2020 ◽  
Vol 105 ◽  
pp. 1-14 ◽  
Author(s):  
Cheng-Hui Xu ◽  
Peng-Ju Ye ◽  
Yang-Chun Zhou ◽  
Dong-Xiu He ◽  
Hua Wei ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Cell Membrane ◽  
Drug Carriers

Hyaluronan based Multifunctional Nano-carriers for Combination Cancer Therapy

2020 ◽  
Vol 20 ◽  
Author(s):  
Menghan Gao ◽  
Hong Deng ◽  
Weiqi Zhang
Keyword(s):  
Cancer Therapy ◽  
Combination Therapy ◽  
Cancer Cells ◽  
Drug Loading ◽  
Tumor Therapy ◽  
Drug Carriers ◽  
Functional Sites ◽  
Therapeutic Modalities ◽  
Combination Cancer Therapy ◽  
Targeting Strategy

: Hyaluronan (HA) is a natural linear polysaccharide that has excellent hydrophilicity, biocompatibility, biodegradability, and low immunogenicity, making it one of the most attractive biopolymers used for biomedical researches and applications. Due to the multiple functional sites on HA and its intrinsic affinity for CD44, a receptor highly expressed on various cancer cells, HA has been widely engineered to construct different drug-loading nanoparticles (NPs) for CD44- targeted anti-tumor therapy. When a cocktail of drugs is co-loaded in HA NP, a multifunctional nano-carriers could be obtained, which features as a highly effective and self-targeting strategy to combat the cancers with CD44 overexpression. The HA-based multidrug nano-carriers can be a combination of different drugs, various therapeutic modalities, or the integration of therapy and diagnostics (theranostics). Up to now, there are many types of HA-based multidrug nano-carriers constructed by different formulation strategies including drug co-conjugates, micelles, nano-gels and hybrid NP of HA and so on. This multidrug nano-carrier takes the full advantages of HA as NP matrix, drug carriers and targeting ligand, representing a simplified and biocompatible platform to realize the targeted and synergistic combination therapy against the cancers. In this review, recent progresses about HA-based multidrug nano-carriers for combination cancer therapy are summarized and its potential challenges for translational applications have been discussed.

scholarly journals Immune Cell Membrane‐Coated Biomimetic Nanoparticles for Targeted Cancer Therapy

Small ◽  
2021 ◽  
pp. 2006484
Author(s):  
Fatemeh Oroojalian ◽  
Mohammad Beygi ◽  
Behzad Baradaran ◽  
Ahad Mokhtarzadeh ◽  
Mohammad‐Ali Shahbazi
Keyword(s):  
Cancer Therapy ◽  
Cell Membrane ◽  
Immune Cell ◽  
Targeted Cancer Therapy ◽  
Biomimetic Nanoparticles

scholarly journals Combination Cancer Therapy Using Chimeric Antigen Receptor-Engineered Natural Killer Cells as Drug Carriers

2017 ◽  
Vol 25 (12) ◽  
pp. 2607-2619 ◽  
Author(s):  
Elizabeth L. Siegler ◽  
Yu Jeong Kim ◽  
Xianhui Chen ◽  
Natnaree Siriwon ◽  
John Mac ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Cancer Therapy ◽  
Natural Killer ◽  
Chimeric Antigen Receptor ◽  
Antigen Receptor ◽  
Drug Carriers ◽  
Killer Cells ◽  
Combination Cancer Therapy

scholarly journals Stimuli Responsive Polymeric Systems for Cancer Therapy

Pharmaceutics ◽  
2018 ◽  
Vol 10 (3) ◽  
pp. 136 ◽  
Author(s):  
Ali Alsuraifi ◽  
Anthony Curtis ◽  
Dimitrios Lamprou ◽  
Clare Hoskins
Keyword(s):  
Cancer Therapy ◽  
Drug Efficacy ◽  
Drug Carriers ◽  
Smart Polymers ◽  
Stimuli Responsive ◽  
Research Focus ◽  
Polymeric Systems ◽  
Effective Strategies ◽  
Targeting Ability ◽  
Patient Side

Nanoscale polymers systems have dominated the revolution of drug delivery advancement. Their potential in the fight against cancer is unrivalled with other technologies. Their functionality increase, targeting ability and stimuli responsive nature have led to a major boom in research focus. This review article concentrates on the use of these smart polymers in cancer therapy. Nanotechnologies have shown potential as drug carriers leading to increased drug efficacy and penetration. Multifunctional smart carriers which can release their payload upon an external or internal trigger such as pH or temperature are proving to be major frontrunners in the development of effective strategies to overcome this disease with minimal patient side effects.

Cancer Cell Membrane Camouflaged Nanoparticles to Realize Starvation Therapy Together with Checkpoint Blockades for Enhancing Cancer Therapy

ACS Nano ◽  
2019 ◽  
Vol 13 (3) ◽  
pp. 2849-2857 ◽  
Author(s):  
Wei Xie ◽  
Wei-Wei Deng ◽  
Minghui Zan ◽  
Lang Rao ◽  
Guang-Tao Yu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Cell Membrane ◽  
Cancer Cell
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