Intervertebral Disc Swelling Maintains Strain Homeostasis Throughout the Annulus Fibrosus: A Finite Element Analysis of Healthy and Degenerated Discs

2019 ◽  
Author(s):  
Bo Yang ◽  
Grace D. O’Connell
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Intervertebral Disc ◽  
Annulus Fibrosus ◽  
Element Analysis

Multiphasic Finite Element Analysis of Physical Signals and Solute Transport in the Human Intervertebral Disc

2004 ◽  
Author(s):  
Hai Yao ◽  
Wei Yong Gu
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Soft Tissue ◽  
Intervertebral Disc ◽  
Mixture Theory ◽  
Element Model ◽  
Tissue Composition ◽  
Element Analysis ◽  
3D Finite Element ◽  
Disc Nutrition

A 3D finite element model for charged hydrated soft tissue containing charged/uncharged solutes was developed based on the multi-phasic mechano-electrochemical mixture theory [1–2]. This model was applied to analyze the mechanical, chemical and electrical signals within the human intervertebral disc under mechanical loading. The effects of tissue composition and material property on the physical signals and the transport of fluid, ions and nutrients were investigated. This study is important for understanding disc biomechanics, disc nutrition and disc mechanobiology.

Designing, Manufacturing and FEA Analyzing of a Intervertebral Disc Made from UHMWPE

2019 ◽  
Vol 957 ◽  
pp. 427-436
Author(s):  
Corneliu Nicolae Druga ◽  
Ileana Constanta Rosca ◽  
Radu Necula
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Intervertebral Disc ◽  
Rapid Prototyping ◽  
Intervertebral Disk ◽  
Cad Model ◽  
Element Analysis ◽  
Fea Analysis

The paper presents a series of aspects regarding the design, manufacturing (through Rapid Prototyping) and FEA analysis of an intervertebral disk made from UHMWPE. In the first part are presented the most used model existing on the market. The CAD model and Finite Element Analysis (FEA) of the intervertebral disc (IVD) were made using the SolidWorks program. As a material, UHMWPE has been preferred due to good mechanical and biocompatibility characteristics.

INFLUENCE OF THE CONSTITUTIVE MATERIAL BEHAVIOR MODEL ASSIGNED TO THE ANNULUS FIBROSUS AND THE NUCLEUS PULPOSUS ON THE BIOMECHANICAL PERFORMANCE OF A MODEL OF THE CERVICAL SPINE: A FINITE ELEMENT ANALYSIS STUDY

2010 ◽  
Vol 10 (01) ◽  
pp. 151-166 ◽  
Author(s):  
YUAN LI ◽  
GLADIUS LEWIS
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Cervical Spine ◽  
Annulus Fibrosus ◽  
Constitutive Models ◽  
Material Behavior ◽  
Elastic Behavior ◽  
Behavior Model ◽  
Element Analysis ◽  
Constitutive Material

One feature of the literature on finite element analysis of models of cervical spine segment(s) is that an assortment of constitutive models has been used for the elastic behavior of the annulus fibrosus (AF) and the nucleus pulposus (NF). The extent to which the model assigned to each of these tissues affects the values of the biomechanical parameters of interest of the model is lacking. This issue was the subject of the present study. We used a three-dimensional solid model of the C4–C6 motion segment units (which comprised the vertebral bodies, the bony posterior elements (transverse processes, pedicles, laminae, spinous processes, and facet joints), the intervertebral discs (IVDs), the endplates, and the five major ligaments) and eight combinations of constitutive models. It was found that (1) the influence of the constitutive material models used depended on the tissue considered, with some, such as the posterior endplate of C5 and the cancellous bone of C6, showing marked sensitivity, while others, such as the cancellous bone of C4 and the cortical bone of C5, were moderately affected; and (2) the biomechanical performance of the spine model is more sensitive to the material behavior model used for the AF than it is to that used for the NF. These results suggest that experimental and computational efforts expended in obtaining the most appropriate constitutive model for the elastic behavior of the two parts of the IVD, in particular the AF, are justified.

Finite Element Analysis of Nutrient Distribution and Cell Viability in Intervertebral Disc: Effect of Compression and Degeneration

2011 ◽  
Author(s):  
Alicia R. Jackson ◽  
Chun-Yuh Huang ◽  
Mark D. Brown ◽  
Weiyong Gu
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Intervertebral Disc ◽  
Human Body ◽  
Cell Activity ◽  
Concentration Gradients ◽  
Nutrient Distribution ◽  
Element Analysis ◽  
Cellular Survival ◽  
Tissue Degeneration

The intervertebral disc (IVD) is the largest avascular structure in the human body. As such, important nutrients, such as glucose and oxygen, that are necessary for cellular survival and functioning, must be transported into the disc via diffusion. As a result, steep concentration gradients develop across the tissue, dependent upon both cellular demand (i.e., metabolism) and transport. Both mechanical loading and tissue degeneration may alter nutrient distributions in the IVD. This may, in turn, affect IVD cell activity and viability.

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