scholarly journals Quantification of the High Level of Endogeneity and of Structural Regime Shifts in Commodity Markets

2013 ◽  
Author(s):  
Vladimir Filimonov ◽  
David Bicchetti ◽  
Nicolas Maystre ◽  
Didier Sornette
Keyword(s):  
Commodity Markets ◽  
Regime Shifts ◽  
Structural Regime ◽  
High Level

scholarly journals Quantification of the high level of endogeneity and of structural regime shifts in commodity markets

2014 ◽  
Vol 42 ◽  
pp. 174-192 ◽  
Author(s):  
Vladimir Filimonov ◽  
David Bicchetti ◽  
Nicolas Maystre ◽  
Didier Sornette
Keyword(s):  
Commodity Markets ◽  
Regime Shifts ◽  
Structural Regime ◽  
High Level

A Long-Run Perspective on Comparative Advantage

2013 ◽  
Author(s):  
Giovanni Federico ◽  
Nikolaus Wolf
Keyword(s):  
Foreign Trade ◽  
Comparative Advantage ◽  
Commodity Markets ◽  
High Concentration ◽  
Long Run ◽  
Trading Partners ◽  
History Of ◽  
High Level ◽  
Global Commodity Markets

The history of Italy since its unification in 1861 was accompanied by a dramatic increase in the country's integration with European and global commodity markets: foreign trade in the long run grew on average faster than the overall economy. Italy's comparative advantage changed fundamentally, from a high concentration of a few trading partners and a handful of rather simple commodities, into a wide diversification of trading partners and more sophisticated commodities. The chapter uses a new long-term database on Italian foreign trade at a high level of disaggregation to document and analyze these changes. The chapter concludes with an assessment of Italy's prospects from a historical perspective.

scholarly journals The Origins of Industrial Conciliation and Arbitration

1964 ◽  
Vol 9 (2) ◽  
pp. 237-254 ◽  
Author(s):  
V. L. Allen
Keyword(s):  
Commodity Markets ◽  
The Other ◽  
Textile Workers ◽  
Trade Unionism ◽  
The North ◽  
Labour Costs ◽  
Low Levels ◽  
High Level ◽  
The Cost ◽  
Wage Cuts

Trade unionism has always involved the settlement of industrial disputes by negotiations between workers' representatives and employers. On occasions in the eighteenth and first half of the nineteenth centuries demands made by workers or employers were granted without question by the other side; at other times the demands were rejected out of hand and this was acquiesced in by the other side. In between these extremes lay a number of possible outcomes. Demands were sometimes conceded after strikes or lockouts or they were moderated and then accepted. The precise outcome depended upon the state of the labour market, and hence the degree of labour organization, and the cost position of the employers. These factors not only varied over time but differed in their intensity between industries and firms at any one point of time. The extreme situations occurred at high and low levels of employment. In the competition for labour, which a high level of employment implies, employers readily gave way to collective demands but as commodity markets deteriorated and the volume of production declined, they at first resisted claims which would have increased labour costs and then deliberately set out to cut wages, lengthen hours and intensify work. Workers commonly resisted initial attempts to reduce labour costs so that a spate of strikes and lockouts ensued. At the onset of the depression in 1819 and at the first suggestion of wage reductions the Lancashire miners, the North Staffordshire potters and the Nottingham framework knitters all responded by striking. The Glasgow cotton spinners resisted wage cuts in 1837 as did the London building workers and miners and textile workers in the midlands and north in 1841 and the typographical workers in 1846. Frequently, however, these disputes resulted in compromise settlements which were superseded by other compromises as trade conditions got worse.

Transcription factor/DNA interactions visualized by electron spectroscopic imaging

1992 ◽  
Vol 50 (1) ◽  
pp. 450-451
Author(s):  
David P. Bazett-Jones ◽  
Mark L. Brown
Keyword(s):  
Transcription Factor ◽  
Dna Sequences ◽  
Transcription Initiation ◽  
Molecular Mechanisms ◽  
Phosphorus Content ◽  
Spectroscopic Imaging ◽  
Electron Spectroscopic Imaging ◽  
Dna Backbone ◽  
Two Parameters ◽  
High Level

A multisubunit RNA polymerase enzyme is ultimately responsible for transcription initiation and elongation of RNA, but recognition of the proper start site by the enzyme is regulated by general, temporal and gene-specific trans-factors interacting at promoter and enhancer DNA sequences. To understand the molecular mechanisms which precisely regulate the transcription initiation event, it is crucial to elucidate the structure of the transcription factor/DNA complexes involved. Electron spectroscopic imaging (ESI) provides the opportunity to visualize individual DNA molecules. Enhancement of DNA contrast with ESI is accomplished by imaging with electrons that have interacted with inner shell electrons of phosphorus in the DNA backbone. Phosphorus detection at this intermediately high level of resolution (≈lnm) permits selective imaging of the DNA, to determine whether the protein factors compact, bend or wrap the DNA. Simultaneously, mass analysis and phosphorus content can be measured quantitatively, using adjacent DNA or tobacco mosaic virus (TMV) as mass and phosphorus standards. These two parameters provide stoichiometric information relating the ratios of protein:DNA content.

Advances in Stem Instrumentation for Biology

1990 ◽  
Vol 48 (1) ◽  
pp. 362-363
Author(s):  
J. S. Wall
Keyword(s):  
Scanning Transmission Electron Microscope ◽  
Carbon Films ◽  
Specimen Preparation ◽  
Material Deposition ◽  
Active User ◽  
Percent Improvement ◽  
Scanning Transmission ◽  
The Moment ◽  
Film Substrate ◽  
High Level

The forte of the Scanning transmission Electron Microscope (STEM) is high resolution imaging with high contrast on thin specimens, as demonstrated by visualization of single heavy atoms. of equal importance for biology is the efficient utilization of all available signals, permitting low dose imaging of unstained single molecules such as DNA.Our work at Brookhaven has concentrated on: 1) design and construction of instruments optimized for a narrow range of biological applications and 2) use of such instruments in a very active user/collaborator program. Therefore our program is highly interactive with a strong emphasis on producing results which are interpretable with a high level of confidence.The major challenge we face at the moment is specimen preparation. The resolution of the STEM is better than 2.5 A, but measurements of resolution vs. dose level off at a resolution of 20 A at a dose of 10 el/A2 on a well-behaved biological specimen such as TMV (tobacco mosaic virus). To track down this problem we are examining all aspects of specimen preparation: purification of biological material, deposition on the thin film substrate, washing, fast freezing and freeze drying. As we attempt to improve our equipment/technique, we use image analysis of TMV internal controls included in all STEM samples as a monitor sensitive enough to detect even a few percent improvement. For delicate specimens, carbon films can be very harsh-leading to disruption of the sample. Therefore we are developing conducting polymer films as alternative substrates, as described elsewhere in these Proceedings. For specimen preparation studies, we have identified (from our user/collaborator program ) a variety of “canary” specimens, each uniquely sensitive to one particular aspect of sample preparation, so we can attempt to separate the variables involved.

A Questionnaire Survey of Current Rehabilitation Practices for Adults With Normal Hearing Sensitivity Who Experience Auditory Difficulties

2020 ◽  
Vol 29 (4) ◽  
pp. 738-761
Author(s):  
Tess K. Koerner ◽  
Melissa A. Papesh ◽  
Frederick J. Gallun
Keyword(s):  
Hearing Aids ◽  
Questionnaire Survey ◽  
Patient Population ◽  
Clinical Care ◽  
Normal Hearing ◽  
Auditory Training ◽  
Training Methods ◽  
Hearing Sensitivity ◽  
Considerable Benefit ◽  
High Level

Purpose A questionnaire survey was conducted to collect information from clinical audiologists about rehabilitation options for adult patients who report significant auditory difficulties despite having normal or near-normal hearing sensitivity. This work aimed to provide more information about what audiologists are currently doing in the clinic to manage auditory difficulties in this patient population and their views on the efficacy of recommended rehabilitation methods. Method A questionnaire survey containing multiple-choice and open-ended questions was developed and disseminated online. Invitations to participate were delivered via e-mail listservs and through business cards provided at annual audiology conferences. All responses were anonymous at the time of data collection. Results Responses were collected from 209 participants. The majority of participants reported seeing at least one normal-hearing patient per month who reported significant communication difficulties. However, few respondents indicated that their location had specific protocols for the treatment of these patients. Counseling was reported as the most frequent rehabilitation method, but results revealed that audiologists across various work settings are also successfully starting to fit patients with mild-gain hearing aids. Responses indicated that patient compliance with computer-based auditory training methods was regarded as low, with patients generally preferring device-based rehabilitation options. Conclusions Results from this questionnaire survey strongly suggest that audiologists frequently see normal-hearing patients who report auditory difficulties, but that few clinicians are equipped with established protocols for diagnosis and management. While many feel that mild-gain hearing aids provide considerable benefit for these patients, very little research has been conducted to date to support the use of hearing aids or other rehabilitation options for this unique patient population. This study reveals the critical need for additional research to establish evidence-based practice guidelines that will empower clinicians to provide a high level of clinical care and effective rehabilitation strategies to these patients.

805: High-Level Cyclin D1 is Associated with High Gleason Grade and Predicts Worse Biochemical-Free Survival in Prostate Cancer

2006 ◽  
Vol 175 (4S) ◽  
pp. 260-260
Author(s):  
Rile Li ◽  
Hong Dai ◽  
Thomas M. Wheeler ◽  
Anna Frolov ◽  
Gustavo Ayala
Keyword(s):  
Prostate Cancer ◽  
Cyclin D1 ◽  
Gleason Grade ◽  
Free Survival ◽  
High Level
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