scholarly journals Effect of buprenorphine on genotoxicity evaluation of chemicals by the rat liver micronucleus test with partial hepatectomy

2015 ◽  
Vol 40 (1) ◽  
pp. 109-114 ◽  
Author(s):  
Satoru Itoh ◽  
Mayumi Nagata ◽  
Chiharu Hattori ◽  
Wataru Takasaki
Keyword(s):  
Partial Hepatectomy ◽  
Rat Liver ◽  
Micronucleus Test ◽  
Liver Micronucleus Test

Gender differences in the liver micronucleus test in rats with partial hepatectomy

2012 ◽  
Vol 214 (3) ◽  
pp. 296-300 ◽  
Author(s):  
Satoru Itoh ◽  
Chiharu Hattori ◽  
Mayumi Nagata ◽  
Wataru Takasaki
Keyword(s):  
Gender Differences ◽  
Partial Hepatectomy ◽  
Micronucleus Test ◽  
Liver Micronucleus Test

DEOXYCYTIDYLATE DEAMINASE LEVELS IN REGENERATING RAT LIVER

1961 ◽  
Vol 39 (6) ◽  
pp. 1043-1054 ◽  
Author(s):  
D. K. Myers ◽  
C. Anne Hemphill ◽  
Constance M. Townsend
Keyword(s):  
Dna Synthesis ◽  
Liver Regeneration ◽  
Partial Hepatectomy ◽  
Rat Liver ◽  
Deoxyribonucleic Acid ◽  
Regenerating Liver ◽  
Regenerating Rat Liver ◽  
High Level ◽  
Early Regeneration

Deoxycytidylate deaminase activity and net synthesis of deoxyribonucleic acid (DNA) in vivo were found to increase at approximately the same time during the early stages of liver regeneration. However, deaminase activity in the regenerating liver remained at a high level for 1 day after DNA synthesis had slowed down again during the later stages of regeneration. The increase in deaminase activity was restricted as a result of exposure to 600 r X radiation during early regeneration, but this effect only became evident 11–16 hours after the irradiation. Irradiation on the second day after partial hepatectomy, when deaminase levels in control regenerating livers were relatively constant, failed to affect the deaminase activity immediately but did produce a 40–50% decrease in activity 11–16 hours later. Other antimitotic agents, e.g., colchicine, had little effect on deaminase activity.

Changes in the expression of lipid-mediated signal-transducing enzymes in the rat Liver after partial hepatectomy

Surgery Today ◽  
2000 ◽  
Vol 30 (7) ◽  
pp. 622-630 ◽  
Author(s):  
Atsushi Watanabe ◽  
Shigeru Nakashima ◽  
Takahito Adachi ◽  
Shigetoyo Saji ◽  
Yoshinori Nozawa
Keyword(s):  
Partial Hepatectomy ◽  
Rat Liver
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