Proliferating effect of orotic acid through mTORC1 activation mediated by negative regulation of AMPK in SK-Hep1 hepatocellular carcinoma cells

Eun-Jeong Jung; Kang-Yo Lee; Byung-Hoon Lee

doi:10.2131/jts.37.813

Proliferating effect of orotic acid through mTORC1 activation mediated by negative regulation of AMPK in SK-Hep1 hepatocellular carcinoma cells

The Journal of Toxicological Sciences ◽

10.2131/jts.37.813 ◽

2012 ◽

Vol 37 (4) ◽

pp. 813-821 ◽

Cited By ~ 3

Author(s):

Eun-Jeong Jung ◽

Kang-Yo Lee ◽

Byung-Hoon Lee

Keyword(s):

Hepatocellular Carcinoma ◽

Orotic Acid ◽

Negative Regulation ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Mtorc1 Activation

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Casticin inhibits stemness of hepatocellular carcinoma cells via disrupting the reciprocal negative regulation between DNMT1 and miR-148a-3p

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2020.114998 ◽

2020 ◽

Vol 396 ◽

pp. 114998

Author(s):

Xiang Li ◽

Lianghou Wang ◽

Xiaocheng Cao ◽

Lingli Zhou ◽

Chang Xu ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Negative Regulation ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells

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Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells

British Journal of Cancer ◽

10.1038/bjc.2014.422 ◽

2014 ◽

Vol 111 (7) ◽

pp. 1327-1337 ◽

Cited By ~ 49

Author(s):

K S Siveen ◽

A H Nguyen ◽

J H Lee ◽

F Li ◽

S S Singh ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Negative Regulation ◽

Carcinoma Cells ◽

Signal Transducer ◽

Hepatocellular Carcinoma Cells ◽

Transcription 3 ◽

Signalling Cascade

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Orotic acid-treated hepatocellular carcinoma cells resist steatosis by modification of fatty acid metabolism

Lipids in Health and Disease ◽

10.1186/s12944-020-01243-5 ◽

2020 ◽

Vol 19 (1) ◽

Author(s):

Johanna Matilainen ◽

Anne-Mari Mustonen ◽

Kirsi Rilla ◽

Reijo Käkelä ◽

Sanna P. Sihvo ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Fatty Acid ◽

Fatty Acid Metabolism ◽

Orotic Acid ◽

Acid Metabolism ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells

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The role of α2, αv and β1 Integrins in cell growth of hepatocellular carcinoma cells in vitro

Zeitschrift für Gastroenterologie ◽

10.1055/s-0037-1612833 ◽

2018 ◽

Vol 56 (01) ◽

pp. E2-E89

Author(s):

M Juratli ◽

A Schnitzbauer ◽

R Blaheta ◽

W Bechstein

Keyword(s):

Hepatocellular Carcinoma ◽

Cell Growth ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Β1 Integrins

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Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-MRP2 antisense constructs

Zeitschrift für Gastroenterologie ◽

10.1055/s-2004-816111 ◽

2004 ◽

Vol 42 (01) ◽

Author(s):

P Hafkemeyer ◽

Y Folmer ◽

C Fulda ◽

H Blum

Keyword(s):

Hepatocellular Carcinoma ◽

Drug Resistance ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Adenoviral Delivery ◽

Antisense Constructs

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HGF/SF downstream signaling in human hepatoblastoma and hepatocellular carcinoma cells

Klinische Pädiatrie ◽

10.1055/s-2004-828568 ◽

2004 ◽

Vol 216 (03) ◽

Author(s):

S Grotegut ◽

E Fasler-Kan ◽

G Christofori ◽

D von Schweinitz

Keyword(s):

Hepatocellular Carcinoma ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Downstream Signaling

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Induction of Apoptosis and Chemosensitization by the Histone Deacetylase Inhibitor Trichostatin in Hepatocellular Carcinoma Cells: Molecular Analysis and RKIP Levels

Forum on Immunopathological Diseases and Therapeutics ◽

10.1615/forumimmundisther.v2.i2.40 ◽

2011 ◽

Vol 2 (2) ◽

pp. 127-135 ◽

Cited By ~ 2

Author(s):

Luigi Inguglia ◽

Monica Notarbartolo ◽

Paola Poma ◽

Manuela Labbozzetta ◽

Natale D'Alessandro

Keyword(s):

Hepatocellular Carcinoma ◽

Histone Deacetylase ◽

Molecular Analysis ◽

Histone Deacetylase Inhibitor ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin ◽

Induction Of Apoptosis

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Apoptotic Effect of Extract from Medicinal Mushroom from Taiwan Taiwanofungus salmoneus (Higher Basidiomycetes) Mycelium Combined with or without Cisplatin on Hepatocellular Carcinoma Cells

International Journal of Medicinal Mushrooms ◽

10.1615/intjmedmushrooms.v17.i6.70 ◽

2015 ◽

Vol 17 (6) ◽

pp. 567-577 ◽

Cited By ~ 2

Author(s):

Rao-Chi Chien ◽

Yun-Jung Hsieh ◽

Jeng-Leun Mau

Keyword(s):

Hepatocellular Carcinoma ◽

Carcinoma Cells ◽

Medicinal Mushroom ◽

Hepatocellular Carcinoma Cells ◽

Apoptotic Effect

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Effects of Liver Cancer Drugs on Cellular Energy Metabolism in Hepatocellular Carcinoma Cells

International Journal of Pharmaceutical Research ◽

10.31838/ijpr/2018.10.03.079 ◽

2018 ◽

Vol 10 (03) ◽

Keyword(s):

Hepatocellular Carcinoma ◽

Energy Metabolism ◽

Liver Cancer ◽

Carcinoma Cells ◽

Cancer Drugs ◽

Hepatocellular Carcinoma Cells ◽

Cellular Energy ◽

Cellular Energy Metabolism

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Faculty Opinions recommendation of Loss of p53 and Ink4a/Arf cooperate in a cell autonomous fashion to induce metastasis of hepatocellular carcinoma cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1090889.544239 ◽

2007 ◽

Author(s):

Shannon Glaser

Keyword(s):

Hepatocellular Carcinoma ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

A Cell

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