Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells

K S Siveen; A H Nguyen; J H Lee; F Li; S S Singh; A P Kumar; G Low; S Jha; V Tergaonkar; K S Ahn; G Sethi

doi:10.1038/bjc.2014.422

Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells

British Journal of Cancer ◽

10.1038/bjc.2014.422 ◽

2014 ◽

Vol 111 (7) ◽

pp. 1327-1337 ◽

Cited By ~ 49

Author(s):

K S Siveen ◽

A H Nguyen ◽

J H Lee ◽

F Li ◽

S S Singh ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Negative Regulation ◽

Carcinoma Cells ◽

Signal Transducer ◽

Hepatocellular Carcinoma Cells ◽

Transcription 3 ◽

Signalling Cascade

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Targeted constitutive activation of signal transducer and activator of transcription 3 in human hepatocellular carcinoma cells by cucurbitacin B

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-008-0780-0 ◽

2008 ◽

Vol 63 (4) ◽

pp. 635-642 ◽

Cited By ~ 49

Author(s):

Meixia Zhang ◽

Hongliang Zhang ◽

Chunyan Sun ◽

Xiaolei Shan ◽

Xiaolin Yang ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Carcinoma Cells ◽

Human Hepatocellular Carcinoma ◽

Signal Transducer ◽

Hepatocellular Carcinoma Cells ◽

Cucurbitacin B ◽

Constitutive Activation ◽

Transcription 3 ◽

Human Hepatocellular Carcinoma Cells

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Identification of β-Escin as a Novel Inhibitor of Signal Transducer and Activator of Transcription 3/Janus-Activated Kinase 2 Signaling Pathway that Suppresses Proliferation and Induces Apoptosis in Human Hepatocellular Carcinoma Cells

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.110.165498 ◽

2010 ◽

Vol 334 (1) ◽

pp. 285-293 ◽

Cited By ~ 95

Author(s):

Sandra Min-Li Tan ◽

Feng Li ◽

Peramaiyan Rajendran ◽

Alan Prem Kumar ◽

Kam M. Hui ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Signaling Pathway ◽

Carcinoma Cells ◽

Human Hepatocellular Carcinoma ◽

Signal Transducer ◽

Hepatocellular Carcinoma Cells ◽

Transcription 3 ◽

Human Hepatocellular Carcinoma Cells

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Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1

Journal of Cellular Physiology ◽

10.1002/jcp.22954 ◽

2012 ◽

Vol 227 (5) ◽

pp. 2184-2195 ◽

Cited By ~ 103

Author(s):

Peramaiyan Rajendran ◽

Feng Li ◽

Muthu K. Shanmugam ◽

Shireen Vali ◽

Taher Abbasi ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Protein Tyrosine Phosphatase ◽

Tyrosine Phosphatase ◽

Carcinoma Cells ◽

Signal Transducer ◽

Hepatocellular Carcinoma Cells ◽

Protein Tyrosine ◽

Transcription 3

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Saikosaponin-d suppresses the expression of cyclooxygenase-2 through the phospho-signal transducer and activator of transcription 3/hypoxia-inducible factor-1α pathway in hepatocellular carcinoma cells

Molecular Medicine Reports ◽

10.3892/mmr.2014.2574 ◽

2014 ◽

Vol 10 (5) ◽

pp. 2556-2562 ◽

Cited By ~ 16

Author(s):

SHUIXIANG HE ◽

GUIFANG LU ◽

HELEI HOU ◽

ZHENJUN ZHAO ◽

ZHANFANG ZHU ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Hypoxia Inducible Factor ◽

Cyclooxygenase 2 ◽

Carcinoma Cells ◽

Signal Transducer ◽

Hepatocellular Carcinoma Cells ◽

Hypoxia Inducible Factor 1Α ◽

Transcription 3

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1056 POSTER Sorafenib Sensitizes Hepatocellular Carcinoma Cells to Radiation-induced Apoptosis Through the Inhibition of Signal Transducers and Activators of Transcription 3

European Journal of Cancer ◽

10.1016/s0959-8049(11)70699-2 ◽

2011 ◽

Vol 47 ◽

pp. S112

Author(s):

K.F. Chen ◽

C.Y. Huang ◽

C.C. Wei ◽

W.T. Tai ◽

A.L. Cheng

Keyword(s):

Hepatocellular Carcinoma ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Signal Transducers ◽

Radiation Induced ◽

Induced Apoptosis ◽

Transcription 3 ◽

Signal Transducers And Activators

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Abstract 2680A: Small molecule induces apoptosis through the inhibition of signal transducers and activators of transcription 3 in hepatocellular carcinoma cells

10.1158/1538-7445.am10-2680a ◽

2010 ◽

Author(s):

Kuen-Feng Chen ◽

Wei-Lin Chen ◽

Wei-Tien Tai ◽

Ann-Lii Cheng ◽

Pei-Jer Chen ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Small Molecule ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Signal Transducers ◽

Transcription 3 ◽

Signal Transducers And Activators

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Long noncoding RNA PVT1 inhibits interferon-α mediated therapy for hepatocellular carcinoma cells by interacting with signal transducer and activator of transcription 1

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2018.04.219 ◽

2018 ◽

Vol 500 (4) ◽

pp. 973-980 ◽

Cited By ~ 10

Author(s):

Hongda Ding ◽

Junpeng Liu ◽

Baiming Liu ◽

Yongchao Zeng ◽

Pengrui Chen ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Long Noncoding Rna ◽

Noncoding Rna ◽

Carcinoma Cells ◽

Interferon Α ◽

Signal Transducer ◽

Hepatocellular Carcinoma Cells

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Proliferating effect of orotic acid through mTORC1 activation mediated by negative regulation of AMPK in SK-Hep1 hepatocellular carcinoma cells

The Journal of Toxicological Sciences ◽

10.2131/jts.37.813 ◽

2012 ◽

Vol 37 (4) ◽

pp. 813-821 ◽

Cited By ~ 3

Author(s):

Eun-Jeong Jung ◽

Kang-Yo Lee ◽

Byung-Hoon Lee

Keyword(s):

Hepatocellular Carcinoma ◽

Orotic Acid ◽

Negative Regulation ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Mtorc1 Activation

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Casticin inhibits stemness of hepatocellular carcinoma cells via disrupting the reciprocal negative regulation between DNMT1 and miR-148a-3p

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2020.114998 ◽

2020 ◽

Vol 396 ◽

pp. 114998

Author(s):

Xiang Li ◽

Lianghou Wang ◽

Xiaocheng Cao ◽

Lingli Zhou ◽

Chang Xu ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Negative Regulation ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells

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Abstract 905: Design and synthesis of regorafenib analogues against signal transducers and activators of transcription 3 in hepatocellular carcinoma cells.

10.1158/1538-7445.am2013-905 ◽

2013 ◽

Author(s):

Jung-Chen Su ◽

Kuen-Feng Chen ◽

Wen-Tien Tai ◽

Jui-Wen Huang ◽

Chung-Wai Shiau

Keyword(s):

Hepatocellular Carcinoma ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Signal Transducers ◽

Design And Synthesis ◽

Transcription 3 ◽

Signal Transducers And Activators

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