Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs

Atsuto Inoue; Yuhei Nishimura; Norihito Matsumoto; Noriko Umemoto; Yasuhito Shimada; Toru Maruyama; Kana Kayasuga; Motohiko Morihara; Jun Katagi; Tsutomu Shiroya; Yasushi Hirota; Soonih Kim; Toshio Tanaka

doi:10.2131/fts.3.79

Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs

Fundamental Toxicological Sciences ◽

10.2131/fts.3.79 ◽

2016 ◽

Vol 3 (2) ◽

pp. 79-87 ◽

Cited By ~ 4

Author(s):

Atsuto Inoue ◽

Yuhei Nishimura ◽

Norihito Matsumoto ◽

Noriko Umemoto ◽

Yasuhito Shimada ◽

...

Keyword(s):

Stem Cell ◽

Comparative Study ◽

Embryonic Stem Cell ◽

Toxicity Test ◽

Developmental Toxicity ◽

Embryonic Stem ◽

Mouse Embryonic Stem Cell ◽

Pharmaceutical Drugs ◽

Cell Test ◽

Embryonic Toxicity

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Relative potency of albendazole and its sulfoxide metabolite in two in vitro tests for developmental toxicity: The rat whole embryo culture and the mouse embryonic stem cell test

Reproductive Toxicology ◽

10.1016/j.reprotox.2012.05.037 ◽

2012 ◽

Vol 34 (3) ◽

pp. 378-384 ◽

Cited By ~ 11

Author(s):

Kathrin Eckardt ◽

Johanna Kaltenhäuser ◽

Caroline Kilb ◽

Andrea Seiler ◽

Ralf Stahlmann

Keyword(s):

Stem Cell ◽

Embryonic Stem Cell ◽

Embryo Culture ◽

Developmental Toxicity ◽

Embryonic Stem ◽

Mouse Embryonic Stem Cell ◽

In Vitro Tests ◽

Whole Embryo Culture ◽

Cell Test

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Prenatal developmental toxicity testing of petroleum substances: Application of the mouse embryonic stem cell test (EST) to compare in vitro potencies with potencies observed in vivo

Toxicology in Vitro ◽

10.1016/j.tiv.2017.07.018 ◽

2017 ◽

Vol 44 ◽

pp. 303-312 ◽

Cited By ~ 11

Author(s):

Lenny Kamelia ◽

Jochem Louisse ◽

Laura de Haan ◽

Ivonne M.C.M. Rietjens ◽

Peter J. Boogaard

Keyword(s):

Stem Cell ◽

Embryonic Stem Cell ◽

Developmental Toxicity ◽

Embryonic Stem ◽

Mouse Embryonic Stem Cell ◽

Toxicity Testing ◽

Cell Test ◽

Developmental Toxicity Testing

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Pre-validation study of alternative developmental toxicity test using mouse embryonic stem cell-derived embryoid bodies

Food and Chemical Toxicology ◽

10.1016/j.fct.2018.10.044 ◽

2019 ◽

Vol 123 ◽

pp. 50-56 ◽

Cited By ~ 1

Author(s):

Jae-Hwan Lee ◽

Seon Young Park ◽

Changhwan Ahn ◽

Cho-Won Kim ◽

Ji-eun Kim ◽

...

Keyword(s):

Stem Cell ◽

Embryonic Stem Cell ◽

Validation Study ◽

Toxicity Test ◽

Developmental Toxicity ◽

Embryonic Stem ◽

Mouse Embryonic Stem Cell ◽

Embryoid Bodies

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Ultrastructure of Three Mouse Embryonic Stem Cell Lines: A Comparative Study

Journal of Stem Cell Research & Therapy ◽

10.4172/2157-7633.1000150 ◽

2013 ◽

Vol 03 (04) ◽

Author(s):

Suzan Alharbi Mona Elsafadi ◽

Mohammed Mobarak Ali Alrwili

Keyword(s):

Stem Cell ◽

Comparative Study ◽

Embryonic Stem Cell ◽

Cell Lines ◽

Embryonic Stem ◽

Mouse Embryonic Stem Cell ◽

Stem Cell Lines

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Developing osteoblasts as an endpoint for the mouse embryonic stem cell test

Reproductive Toxicology ◽

10.1016/j.reprotox.2015.04.008 ◽

2015 ◽

Vol 53 ◽

pp. 131-140 ◽

Cited By ~ 9

Author(s):

Xinrong Chen ◽

Deborah K. Hansen ◽

Gwenn Merry ◽

Christian DeJarnette ◽

Greg Nolen ◽

...

Keyword(s):

Stem Cell ◽

Embryonic Stem Cell ◽

Embryonic Stem ◽

Mouse Embryonic Stem Cell ◽

Cell Test

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Relative Developmental Toxicity of Glycol Ether Alkoxy Acid Metabolites in the Embryonic Stem Cell Test as compared with the In Vivo Potency of their Parent Compounds

Toxicological Sciences ◽

10.1093/toxsci/kfp083 ◽

2009 ◽

Vol 110 (1) ◽

pp. 117-124 ◽

Cited By ~ 51

Author(s):

Esther de Jong ◽

Jochem Louisse ◽

Miriam Verwei ◽

Bas J. Blaauboer ◽

Johannes J. M. van de Sandt ◽

...

Keyword(s):

Stem Cell ◽

Embryonic Stem Cell ◽

Developmental Toxicity ◽

Embryonic Stem ◽

Glycol Ether ◽

Cell Test ◽

Acid Metabolites

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The embryonic toxicity evaluation of deoxynivalenol (DON) by murine embryonic stem cell test and human embryonic stem cell test models

Food Control ◽

10.1016/j.foodcont.2017.10.018 ◽

2018 ◽

Vol 86 ◽

pp. 234-240 ◽

Cited By ~ 7

Author(s):

Haiqin Fang ◽

Yuan Zhi ◽

Zhou Yu ◽

Robert A. Lynch ◽

Xudong Jia

Keyword(s):

Stem Cell ◽

Embryonic Stem Cell ◽

Human Embryonic Stem Cell ◽

Embryonic Stem ◽

Toxicity Evaluation ◽

Murine Embryonic Stem Cell ◽

Test Models ◽

Cell Test ◽

Embryonic Toxicity

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Relative developmental toxicity of glycol ethers in the embryonic stem cell test and comparison to their in vivo potency ranking

Reproductive Toxicology ◽

10.1016/j.reprotox.2009.05.041 ◽

2009 ◽

Vol 28 (2) ◽

pp. 133

Author(s):

Esther de Jong ◽

Jochem Louisse ◽

Miriam Verwei ◽

Bas J. Blaauboer ◽

Han van de Sandt ◽

...

Keyword(s):

Stem Cell ◽

Embryonic Stem Cell ◽

Developmental Toxicity ◽

Embryonic Stem ◽

Glycol Ethers ◽

Cell Test ◽

Potency Ranking

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Combination of the BeWo b30 placental transport model and the embryonic stem cell test to assess the potential developmental toxicity of silver nanoparticles

Particle and Fibre Toxicology ◽

10.1186/s12989-020-00342-6 ◽

2020 ◽

Vol 17 (1) ◽

Cited By ~ 2

Author(s):

Ashraf Abdelkhaliq ◽

Meike van der Zande ◽

Ruud J. B. Peters ◽

Hans Bouwmeester

Keyword(s):

Silver Nanoparticles ◽

Stem Cell ◽

Embryonic Stem Cell ◽

Transport Model ◽

Developmental Toxicity ◽

Embryonic Stem ◽

Placental Transport ◽

Bewo B30 ◽

Cell Test

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Gene set assembly for quantitative prediction of developmental toxicity in the embryonic stem cell test

Toxicology ◽

10.1016/j.tox.2011.03.017 ◽

2011 ◽

Vol 284 (1-3) ◽

pp. 63-71 ◽

Cited By ~ 27

Author(s):

Jeroen L.A. Pennings ◽

Dorien A.M. van Dartel ◽

Joshua F. Robinson ◽

Tessa E. Pronk ◽

Aldert H. Piersma

Keyword(s):

Stem Cell ◽

Embryonic Stem Cell ◽

Developmental Toxicity ◽

Embryonic Stem ◽

Quantitative Prediction ◽

Gene Set ◽

Cell Test

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