Assessment of Potential of First Trimester Ultrasonography in Detection of Fetal Congenital Structural Malformations- A Retrospective Study

2019 ◽  
Vol 7 (2) ◽  
pp. 52-55
Author(s):  
G Rajesh ◽  
◽  
Waseem Akhtar ◽  
Keyword(s):  
Retrospective Study ◽  
First Trimester

scholarly journals Comparison between laparoscopy and laparotomy in the management of ectopic pregnancy: a retrospective study

2020 ◽  
Vol 9 (2) ◽  
pp. 705
Author(s):  
Suneeta Singh ◽  
Namrita Sandhu ◽  
Sanjay Singh ◽  
Praveen Kumar ◽  
Atiya Aziz
Keyword(s):  
Retrospective Study ◽  
Ectopic Pregnancy ◽  
Perioperative Complications ◽  
Operating Time ◽  
Laparoscopic Approach ◽  
First Trimester ◽  
Laparoscopy Group ◽  
Group I ◽  
Duration Of Surgery ◽  
Laparotomy Group

Background: Ectopic pregnancy is one of the most important causes of maternal mortality and morbidity in the first trimester of pregnancy. Objective of this study was to compare the safety, feasibility and advantage of laparoscopic approach with that of laparotomy in management of ectopic pregnancy.Methods: A retrospective study was conducted at two tertiary hospitals over a period of two years i.e.; from Aug 2015 to July 2017. Seventy-five patients who had histopathology confirmed tubal ectopic pregnancy were divided into two groups; laparoscopy (Group I, no-39) and laparotomy (Group II no-36). The main outcome measures were operative time, blood loss, and requirement of blood transfusion, requirement of analgesia and duration of hospital stay.Results: Seventy-five patients of ectopic pregnancy who were managed surgically were studied. There were 39 cases in laparoscopy group and 36 cases in laparotomy group. The incidence of ectopic pregnancy was 1.56% (out of all deliveries over 2 years). Ampullary region was the commonest site of ectopic pregnancy (74.6%). No difference was found in the two groups regarding age, site of tubal pregnancy, pre op Hb status and haemoperitoneum. Mean operating time was significantly shorter in the laparoscopy group 39 min (range 30 - 52 min) versus 50 min (range 40-60 min) in the laparotomy group. There was no difference between the groups regarding the treatment with blood products and perioperative complications. Hospital stay was significantly longer in the laparotomy group (3.5 days) as compared to 2 days in laparoscopy group. The duration of post op analgesia requirement was also longer in laparotomy group (4 days) as compared to 2 days in laparoscopy group.Conclusions: Laparoscopic management of ectopic pregnancy is a safe, effective and beneficial option in the hands of an experienced laparoscopic surgeon even in cases of massive haemoperitoneum. It definitely offers the advantage of shorter duration of surgery, faster post op recovery, shorter duration of hospital stays and lesser requirement of post op analgesia.

scholarly journals Clinical study of ectopic pregnancy at tertiary care center in Haryana, India

2019 ◽  
Vol 8 (7) ◽  
pp. 2816
Author(s):  
Sushila Chaudhary ◽  
Meenakshi B. Chauhan ◽  
Anjali Gupta ◽  
Monika Dalal
Keyword(s):  
Retrospective Study ◽  
Ectopic Pregnancy ◽  
Care Center ◽  
Tertiary Care ◽  
First Trimester ◽  
Sexual Practices ◽  
Care Hospital ◽  
Threatening Condition ◽  
Incidence Risk ◽  
Β Hcg

Background: Ectopic pregnancy is a life threatening condition in the first trimester of pregnancy. Diagnosis can be done by clinical examination, serum β-HCG and ultrasonography. This retrospective study was done to know the incidence, risk factors, and management of ectopic pregnancy.Methods: It was a retrospective study conducted on 75 patients of ectopic pregnancy admitted at tertiary care hospital in Haryana from February-2017 to January-2019. Data collected from record room and analysis done.Results: Total deliveries were conducted were 5064. The incidence of ectopic pregnancy was 1.48%, majority of the women were in the age group of 21-30 (68%), multi-parous (77.32%). The most common risk factor was abortion 33.33%, f/b tubal ligation was 13.13%, medical management of ectopic pregnancy done in 30.66%, 8% were managed by laproscopically and 58.66% by laparotomy.Conclusions: Safe sexual practices can reduce pelvic infections and ectopic pregnancy incidences. Early diagnosis before tubal rupture can reduce morbidity and mortality in ectopic pregnancy.

scholarly journals Utility of First Trimester Ultrasonography before 11 Weeks of Gestation: A Retrospective Study

2012 ◽  
Vol 2012 ◽  
pp. 1-6
Author(s):  
Sevki Celen ◽  
Necmiye Dover ◽  
Berna Seckin ◽  
Ufuk Goker ◽  
Okan Yenicesu ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Gestational Age ◽  
Pregnancy Outcomes ◽  
Maternal Age ◽  
First Trimester ◽  
Antenatal Clinic ◽  
Ovarian Cysts ◽  
Chi Square ◽  
Uterine Anomalies ◽  
Chi Square Tests

We showed the utility of first trimester ultrasonography before 11 weeks of gestation for antenatal followup. We retrospectively analyzed 1295 records of patients who underwent first trimester ultrasonography (transvaginal/abdominal) in our antenatal clinic in Ankara, Turkey. Maternal age, parity, gestational age, and maternal gestational history were compared with ultrasonographic findings. Patients were divided into 12 groups based on ultrasonographic diagnoses in the first ultrasonographic scan, and called for a control examination within 10 days if the diagnostic findings were abnormal. The data were statistically analyzed using Kruskal-Wallis and chi-square tests. We noted 81.3% patients to have single, viable, intrauterine pregnancies, while 18.7% had abnormal or complicated pregnancies with uterine anomalies, ovarian cysts, fibroids, or subchorionic hematomas. Normal and anembryonic pregnancies had significantly lower median diagnostic period in the control ultrasonography than in the first examination. First trimester ultrasonography before 11 weeks of gestation is valuable in determining pregnancy outcomes.

First trimester serum PAPP-A is associated with placenta accreta: a retrospective study

2021 ◽  
Author(s):  
Fengge Wang ◽  
Shuxiong Chen ◽  
Jishui Wang ◽  
Yangping Wang ◽  
Fang Ruan ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Placenta Accreta ◽  
First Trimester

scholarly journals Performance and the Optimal Cut-Off Value of First-Trimester Fasting Plasma Glucose To Identify Gestational Diabetes Mellitus: A Retrospective Study From Southern China

2021 ◽  
Author(s):  
Jia-Ning Tong ◽  
Lin-Lin Wu ◽  
Yi-Xuan Chen ◽  
Xiao-Nian Guan ◽  
Kan Liu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Retrospective Study ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Maternal Age ◽  
First Trimester ◽  
Fasting Plasma

Abstract Purpose Previous studies have suggested that first-trimester fasting plasma glucose (FPG) is associated with gestational diabetes mellitus (GDM) and is a predictor of GDM. The aim of the present study was to explore whether first-trimester FPG levels can be used as a screening and diagnostic test for GDM in pregnant women. Methods This retrospective study included pregnant women who had their first-trimester FPG recorded at 9-13+6 weeks and underwent screening for GDM using the 2-hour 75 g oral glucose tolerance test (OGTT) between 24th and 28th gestational weeks. The cut-off values were calculated using a receiver operating characteristic (ROC) curve. Results The medical records of 28,030 pregnant women were analysed, and 4,669 (16.66%) of them were diagnosed with GDM. The mean first-trimester FPG was 4.62 ± 0.37 mmol/L. The total trend in the optimal cut-off value of first-trimester FPG in pregnant women was 4.735 mmol/L, with a sensitivity of 49%, a specificity of 67.6% and AUC of 0.608 (95% CI: 0.598-0.617, p༜0.001). Moreover, as the maternal age increased, the optimal cut-off values increased, respectively. The results suggest that first-trimester FPG can be considered a marker for identifying pregnant women with GDM. Conclusion The level of first-trimester FPG increased slightly with maternal age and, as maternal age increased, the optimal cut-off values increased, especially after age 30. The first-trimester FPG should be considered a screening marker when diagnosing GDM in pregnant women.

scholarly journals Clinical profile and outcome of congenital cyanotic heart disease in neonatal period: a retrospective study

2020 ◽  
Vol 7 (2) ◽  
pp. 311
Author(s):  
Janaki B. Pradhan ◽  
C. N. Kamalarathnam
Keyword(s):  
Heart Disease ◽  
Retrospective Study ◽  
Neonatal Period ◽  
Pulmonary Atresia ◽  
Fetal Distress ◽  
First Trimester ◽  
Cyanotic Heart Disease ◽  
Trimester Abortion ◽  
Maternal Risk ◽  
Congenital Cyanotic Heart Disease

Background: Congenital Cyanotic Heart Disease (CCHD) is under reported during neonatal period and mortality rate is high in India. Aims and objectives of the study determine clinical presentation, maternal and neonatal risk factors and outcome of CCHD during neonatal period.Methods: A retrospective study conducted over 15-month period during March 2017 to June 2018 in a tertiary out born NICU. Neonates with echocardiographically confirmed case of structurally abnormal heart disease were analyzed.Results: Among 106 CCHD neonates, 60% neonates were asymptomatic, 22% had persistent cyanosis and 19% had tachypneic at birth. Cyanosis (35%) and tachypnea (30%) were common initial presentation in postnatal period. 22% neonates were readmitted with initial clinical symptom after discharge from birthing centre. CCHD were more common in male and term neonate, 34% were small for age, median age at admission and discharge were 5days (2-12) and 5 days (2.7-9.2) days respectively. Nineteen percent neonates had fetal distress and 6% neonates required aggressive resuscitation at birth. First trimester abortion (16%), maternal diabetes (10%) and hypothyroidism (7%) were common maternal risk factor. Nearly 20% neonates were diagnosed at referring hospital and 4.7% were transported with PGE1 during transport. TGA (17%) was most common lesion noted followed by pulmonary atresia (10%). Fourteen percent neonates died during the neonatal period. Disease specific death rate was highest for Single ventricle (42%) followed by TGA with IVS (37.5%) and aortic arch anomaly (28.5%) in this study.Conclusions: Early diagnosis and management may improve the survival in CCHD neonates.

scholarly journals The Effects of LIT and MLR-Bf on Immune Biomarkers and Pregnancy Outcomes in Women With Previous Early Recurrent Miscarriage: A Retrospective Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Lili Meng ◽  
Jianping Tan ◽  
Tao Du ◽  
Xianghua Lin ◽  
Shuning Zhang ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Pregnancy Outcomes ◽  
Recurrent Miscarriage ◽  
First Trimester ◽  
Successful Pregnancy ◽  
Immunological Failure ◽  
Maternal Immune System ◽  
Immune Biomarkers ◽  
Blocking Factors ◽  
Lymphocyte Immunotherapy

Background: Immunological failure during pregnancy is considered one of the etiologies of recurrent miscarriage (RM). The decreased production of mixed lymphocyte reaction-blocking factors (MLR-Bf) may play a major role in this condition. Lymphocyte immunotherapy (LIT), which induces the production of MLR-Bf, has been used in treating RM patients since 1984. However, the effectiveness of LIT is currently being heatedly debated. In addition to that, possible changes to the maternal immune system upon induced MLR-Bf production by LIT remains unclear.Objectives: To explore the possible impacts that MLR-Bf may have on the expression of immune biomarkers and pregnancy outcomes, and deduce whether the prevention of miscarriages is possible with LIT or MLR-Bf in RM patients.Materials and Methods: Women with previous early RM (eRM) were enrolled in this retrospective study after they got pregnant again. LIT was implemented before pregnancy and during the first trimester. MLR-Bf and immune biomarkers were checked as the clinical routine. Patients were followed up until 12 gestational weeks. Levels of immune biomarkers and successful pregnancy rates were compared between MLR-Bf− group and MLR-Bf+ group stratified by LIT. Independent associations between LIT, or MLR-Bf, and miscarriage were estimated. All data management and analysis were conducted using SPSS 20.0.Results: A total of 1,038 patients, 497 MLR-Bf− (49 cases accepted LIT), and 541 MLR-Bf+(463 cases induced by LIT) were included in the study. Percentage of lymphocytes, the ratio of CD4+ T cells/lymphocytes, and levels of some rheumatoid biomarkers (anti-U1-nRNP, anti-SAA-52kd, and anti-CENOP B) were statistically higher in MLR-Bf+ group than in MLR-Bf− group among women without LIT. With LIT treatment the successful pregnancy rate was statistically higher in MLR-Bf+ group than in MLR-Bf− group (66.7% vs. 51.0%, P = 0.028) among women with LIT. Meanwhile, LIT was estimated to have an independent negative association with miscarriage.Conclusion: Upon LIT treament levels of immune biomarkers were different in women with and without MLR-Bf when stratified by whether they received LIT. Not MLR-Bf, but LIT, has an independent protective effect on miscarriage.

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