Sustainable Precision Green Manufacturing: Advanced Hybrid Reactive Armor Materials

2014 ◽  
Author(s):  
Diana-Lynn Herbst ◽  
Leonard J. Mecca
Keyword(s):  
Green Manufacturing

Formulation of Extended-Release Beads of Lamotrigine Based on Alginate and Cassia fistula Seed Gum by QbD Approach

2020 ◽  
Vol 17 (5) ◽  
pp. 422-437
Author(s):  
Dixita Jain ◽  
Akshay Sodani ◽  
Swapnanil Ray ◽  
Pranab Ghosh ◽  
Gouranga Nandi
Keyword(s):  
Drug Release ◽  
Factorial Design ◽  
Extended Release ◽  
Polymer Concentration ◽  
Green Manufacturing ◽  
Full Factorial Design ◽  
Cassia Fistula ◽  
Negative Environmental Impact ◽  
Seed Gum ◽  
Full Factorial

Aim: This study was focused on the formulation of the multi-unit extended-release peroral delivery device of lamotrigine for better management of epilepsy. Background: The single-unit extended-release peroral preparations often suffer from all-or-none effect. A significant number of multi-unit delivery systems have been reported as a solution to this problem. But most of them are found to be composed of synthetic, semi-synthetic or their combination having physiological toxicity as well as negative environmental impact. Therefore, fabrication and formulation of multi-unit extended-release peroral preparations with natural, non-toxic, biodegradable polymers employing green manufacturing processes are being appreciated worldwide. Objective: Lamotrigine-loaded extended-release multi-unit beads have been fabricated with the incorporation of a natural polysaccharide Cassia fistula seed gum in calcium-cross-linked alginate matrix employing a simple green process and 23 full factorial design. Methods: The total polymer concentration, polymer ratio and [CaCl2] were considered as independent formulation variables with two different levels of each for the experiment-design. The extended-release beads were then prepared by the ionotropic gelation method using calcium chloride as the crosslinkerions provider. The beads were then evaluated for drug encapsulation efficiency and drug release. ANOVA of all the dependent variables such as DEE, cumulative % drug release at 2h, 5h, 12h, rate constant and dissolution similarity factor (f2) was done by 23 full factorial design using Design-Expert software along with numerical optimization of the independent variables in order to meet USP-reference release profile. Results: The optimized batch showed excellent outcomes with DEE of 84.7 ± 2.7 (%), CPR2h of 8.41± 2.96 (%), CPR5h of 36.8± 4.7 (%), CPR12h of 87.3 ± 3.64 (%) and f2 of 65.9. Conclusion: This approach of the development of multi-unit oral devices utilizing natural polysaccharides might be inspiring towards the world-wide effort for green manufacturing of sustained-release drug products by the QbD route.

Research on Basic Standard of Roadmap for Green Manufacturing

2014 ◽  
Vol 484-485 ◽  
pp. 462-466
Author(s):  
Zi Xing Gao
Keyword(s):  
Green Manufacturing ◽  
Modern Management ◽  
Preliminary Discussion ◽  
Road Map ◽  
Basic Standard

The technical roadmap which has been produced since the 1980s is used in many fields. In reality it has formed many technical roadmaps standard. Summarizing and studying these standards has the important meaning to this emerging modern management tool's development consummation of the technical road map. This article has carried on the preliminary discussion from the technical roadmap content, the formulation procedure, the representation, the formulation method and so on.

Developing green manufacturing indicators for the decorative paint industry: A case study of Indonesia

2020 ◽  
Author(s):  
Gun Nanda Tian Purnama ◽  
Sawarni Hasibuan ◽  
Zulfa Fitri Ikatrinasari
Keyword(s):  
Green Manufacturing ◽  
Paint Industry

Study on a Green Manufacturing Process Design System

2013 ◽  
Vol 397-400 ◽  
pp. 57-61
Author(s):  
Dong Jie Zhong
Keyword(s):  
Process Design ◽  
Manufacturing Process ◽  
Design Principle ◽  
Green Manufacturing ◽  
Design System ◽  
Operation Flow

Green manufacturing process is a key segment to guarantee green degree of products manufacturing course. In this paper, a kind of design system is presented by analyzing the function demand of the design system for green manufacturing process and then the modules which constituent the design system are analyzed in detail. Moreover, according to the design principle and the estimate indexes of green manufacturing process, the operation flow of the design system is introduced.

scholarly journals Green Manufacturing: A Key to Innovation Economy

2016 ◽  
Vol 2 (4) ◽  
pp. 273-275 ◽  
Author(s):  
Veena Sahajwalla ◽  
Farshid Pahlevani ◽  
Samane Maroufi ◽  
Ravindra Rajarao
Keyword(s):  
Green Manufacturing ◽  
Innovation Economy

A Study on the Green Design of Ceramic Products in the Era of Information

2014 ◽  
Vol 633-634 ◽  
pp. 347-350
Author(s):  
Hui Huang ◽  
Jun Jian Liu
Keyword(s):  
Life Cycle ◽  
Environmental Pollution ◽  
Green Manufacturing ◽  
Green Design ◽  
Function Structure ◽  
Package Design ◽  
Component Design ◽  
Material Component ◽  
Product Function ◽  
And Function

The green design of ceramic products in the era of information should pay attention to quality, lifetime and function of products, and should consider green design of product function, structure and material, component design as well as life cycle. This paper studied the green manufacturing during molding and firing, the green decorative and package design of ceramic products to improve the reclamation rate of production, disassembly and recycle in the life cycle for the decrease of environmental pollution due to wastes.

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