Modeling Biomimetic Mineralization

2010 ◽  
Author(s):  
Murugappan Muthukumar
Keyword(s):  
Biomimetic Mineralization

scholarly journals Morphogenesis and evolution mechanisms of bacterially-induced struvite

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tian-Lei Zhao ◽  
Han Li ◽  
Hao-Fan Jiang ◽  
Qi-Zhi Yao ◽  
Ying Huang ◽  
...  
Keyword(s):  
Time Course ◽  
Carboxyl Groups ◽  
Precipitation Process ◽  
Phosphate Content ◽  
Biomimetic Mineralization ◽  
Struvite Precipitation ◽  
Growth Habits ◽  
Two Stages ◽  
Relevant Work ◽  
Insight Into

AbstractBacteria are able to induce struvite precipitation, and modify struvite morphology, leading to the mineral with various growth habits. However, the relevant work involving the morphogenesis is limited, thereby obstructing our understanding of bacterially mediated struvite mineralization. Here, an actinomycete Microbacterium marinum sp. nov. H207 was chosen to study its effect on struvite morphology. A combination of bacterial mineralization and biomimetic mineralization techniques was adopted. The bacterial mineralization results showed that strain H207 could induce the formation of struvite with grouping structure (i.e., a small coffin-like crystal grown on a large trapezoid-like substrate crystal), and the overgrowth structure gradually disappeared, while the substrate crystal further evolved into coffin-like, and quadrangular tabular morphology with time. The biomimetic experiments with different organic components confirmed that the soluble macromolecules rich in electronegative carboxyl groups secreted by strain H207 dominate the formation of the struvite grouping. The time-course biomimetic experiments with supernatant testified that the increase in pH and NH4+ content promoted the evolution of crystal habits. Moreover, the evolution process of substrate crystal can be divided into two stages. At the first stage, the crystal grew along the crystallographic b axis. At the later stage, coupled dissolution–precipitation process occurred, and the crystals grew along the corners (i.e., [110] and [1-10] directions). In the case of dissolution, it was also found that the (00-1) face of substrate crystal preferentially dissolved, which results from the low initial phosphate content and high PO43− density on this face. As a result, present work can provide a deeper insight into bio-struvite mineralization.

scholarly journals Lactoferrin/Calcium Phosphate-Modified Porous Ti by Biomimetic Mineralization: Effective Infection Prevention and Excellent Osteoinduction

Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 992
Author(s):  
Song Chen ◽  
Yuanli He ◽  
Linna Zhong ◽  
Wenjia Xie ◽  
Yiyuan Xue ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Photoelectron Spectroscopy ◽  
Antibacterial Properties ◽  
Biomimetic Mineralization ◽  
Matrix Mineralization ◽  
X Ray ◽  
Porous Ti ◽  
Potential Applications ◽  
Modification Of Titanium

The surface modification of titanium (Ti) can enhance the osseointegration and antibacterial properties of implants. In this study, we modified porous Ti discs with calcium phosphate (CaP) and different concentrations of Lactoferrin (LF) by biomimetic mineralization and examined their antibacterial effects and osteogenic bioactivity. Firstly, scanning electron microscopy (SEM), the fluorescent tracing method, X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and the releasing kinetics of LF were utilized to characterize the modified Ti surface. Then, the antibacterial properties against S. sanguis and S. aureus were investigated. Finally, in vitro cytological examination was performed, including evaluations of cell adhesion, cell differentiation, extracellular matrix mineralization, and cytotoxicity. The results showed that the porous Ti discs were successfully modified with CaP and LF, and that the LF-M group (200 μg/mL LF in simulated body fluid) could mildly release LF under control. Further, the LF-M group could effectively inhibit the adhesion and proliferation of S. sanguis and S. aureus and enhance the osteogenic differentiation in vitro with a good biocompatibility. Consequently, LF-M-modified Ti may have potential applications in the field of dental implants to promote osseointegration and prevent the occurrence of peri-implantitis.

Biomimetic mineralization of metal–organic frameworks around polysaccharides

2017 ◽  
Vol 53 (7) ◽  
pp. 1249-1252 ◽  
Author(s):  
Kang Liang ◽  
Ru Wang ◽  
Manon Boutter ◽  
Cara M. Doherty ◽  
Xavier Mulet ◽  
...  
Keyword(s):  
Metal Organic Frameworks ◽  
Functional Materials ◽  
Biomimetic Mineralization ◽  
Metal Organic

Biomimetic mineralization exploits natural biomineralization processes for the design and fabrication of synthetic functional materials.

Facile Fabrication of Organic–Inorganic Hybrid Beads by Aminated Alginate Enabled Gelation and Biomimetic Mineralization

2012 ◽  
Vol 24 (2) ◽  
pp. 119-134 ◽  
Author(s):  
Jian Li ◽  
Hong Wu ◽  
Yanpeng Liang ◽  
Zhongyi Jiang ◽  
Yanjun Jiang ◽  
...  
Keyword(s):  
Biomimetic Mineralization ◽  
Inorganic Hybrid ◽  
Facile Fabrication
Sign in / Sign up

Export Citation Format

Share Document