Independent Review Panel Report on the Defense Contract Audit Agency

2008 ◽  
Author(s):  
DEFENSE BUSINESS BOARD WASHINGTON DC
Keyword(s):  
Review Panel ◽  
Panel Report ◽  
Defense Contract ◽  
Independent Review

scholarly journals Pantex Falling Man - Independent Review Panel Report.

2014 ◽  
Author(s):  
Louis Bertolini ◽  
Nathan Brannon ◽  
Jared Olson ◽  
Bernard Price ◽  
Robert Wardle ◽  
...  
Keyword(s):  
Review Panel ◽  
Panel Report ◽  
Independent Review ◽  
Falling Man

Report of an independent peer review of an acrylonitrile risk assessment

2005 ◽  
Vol 24 (10) ◽  
pp. 487-527 ◽  
Author(s):  
L T Haber ◽  
J Patterson
Keyword(s):  
Risk Assessment ◽  
Peer Review ◽  
Dose Response ◽  
Environmental Protection Agency ◽  
Mode Of Action ◽  
Response Assessment ◽  
Weight Of Evidence ◽  
Protection Agency ◽  
Review Panel ◽  
Independent Review

A peer review panel made up of experts in toxicology, epidemiology, cancer mode of action (MOA), cancer mechanisms, carcinogenicity, genotoxicity, dose–response, US Environmental Protection Agency (EPA) cancer and noncancer methods, pharmacokinetic modeling and acrylonitrile, met on 22–23 September 2003 in Cincinnati, OH. The purpose of the meeting was to provide an independent review of a risk assessment of acrylonitrile that had been prepared by the Acrylonitrile Group (AN Group). Toxicology Excellence for Risk Assessment (TERA) organized the peer review and selected the panel. The panel discussed the toxicity and epidemiology literature of acrylonitrile and MOA information, and reached conclusions regarding its MOA, weight of evidence (WOE) for carcinogenicity, preferred approach for dose-response assessment and risk values. This paper summarizes the discussion and conclusions of the panel regarding the acrylonitrile assessment. Subsequent to the peer review, the authors of the acrylonitrile assessment revised their report and the panel reviewed the revised report. A manuscript of the revised assessment is being published in Regulatory Toxicology and Pharmacology.

Pivotal Study of Iodine I 131 Tositumomab for Chemotherapy-Refractory Low-Grade or Transformed Low-Grade B-Cell Non-Hodgkin’s Lymphomas

2001 ◽  
Vol 19 (19) ◽  
pp. 3918-3928 ◽  
Author(s):  
Mark S. Kaminski ◽  
Andrew D. Zelenetz ◽  
Oliver W. Press ◽  
Mansoor Saleh ◽  
John Leonard ◽  
...  
Keyword(s):  
Complete Response ◽  
Low Grade ◽  
Efficacy And Safety ◽  
Review Panel ◽  
Pivotal Study ◽  
Duration Of Response ◽  
Independent Review ◽  
Pretreated Patients ◽  
Hodgkin's Lymphomas

PURPOSE: To evaluate the efficacy and safety of tositumomab and iodine I 131 tositumomab (Bexxar; Corixa Corp, Seattle, WA, and GlaxoSmithKline, Philadelphia, PA) in patients with chemotherapy-refractory low-grade or transformed low-grade non-Hodgkin’s lymphoma (NHL) and to compare its efficacy to the patients’ last qualifying chemotherapy (LQC) regimens. PATIENTS AND METHODS: Sixty patients who had been treated with at least two protocol-specified qualifying chemotherapy regimens and had not responded or progressed within 6 months after their LQC were treated with a single course of iodine I 131 tositumomab. RESULTS: Patients had received a median of four prior chemotherapy regimens. A partial or complete response (CR) was observed in 39 patients (65%) after iodine I 131 tositumomab, compared with 17 patients (28%) after their LQC (P < .001). The median duration of response (MDR) was 6.5 months after iodine I 131 tositumomab, compared with 3.4 months after the LQC (P < .001). Two patients (3%) had a CR after their LQC, compared with 12 (20%) after iodine I 131 tositumomab (P < .001). The MDR for CR was 6.1 months after the LQC and had not been reached with follow-up of more than 47 months after iodine I 131 tositumomab. An independent review panel verified that 32 (74%) of the 43 patients with nonequivalent durations of response (> 30 days difference) had a longer duration of response after iodine I 131 tositumomab (P < .001). Only one patient was hospitalized for neutropenic fever. Five patients (8%) developed human antimurine antibodies, and one (2%) developed an elevated TSH level after treatment. Myelodysplasia was diagnosed in four patients in follow-up. CONCLUSION: A single course of iodine I 131 tositumomab was significantly more efficacious than the LQC received by extensively pretreated patients with chemotherapy-refractory, low-grade, or transformed low-grade NHL and had an acceptable safety profile.

scholarly journals Use of a Retrospective Methodology to Examine the Process of Care Surrounding Serious Medical Events in HIV-Positive Patients: A Feasibility Study

2019 ◽  
Vol 18 ◽  
pp. 232595821986874
Author(s):  
Erica R M Pool ◽  
Vanessa Cooper ◽  
Elaney Youssef ◽  
Juliet Wright ◽  
Jordan Skittrall ◽  
...  
Keyword(s):  
Medical Records ◽  
Review Process ◽  
Models Of Care ◽  
Hiv Positive ◽  
People Living With Hiv ◽  
Process Of Care ◽  
Review Panel ◽  
Care Processes ◽  
Independent Review ◽  
Living With Hiv

Introduction: Comorbidities are increasingly common among people living with HIV (PLWH) as they age. There is no evidence regarding models of care. We aimed to assess feasibility of a novel methodology to investigate care processes for serious medical events in PLWH. Method: The method was based on the National Confidential Enquiry into Patient Outcome and Death (NCEPOD). Data were extracted from medical records and questionnaires completed by general practitioners (GPs), HIV physicians, and non-HIV specialist physicians. A panel reviewed anonymized cases and gave feedback on the review process. Results: Eleven of 13 patients consented to the study. Questionnaires were completed by 64% of HIV physicians, 67% of non-HIV specialist physicians, and 55% of GPs. The independent review panel (IRP) advised improvement in the methodology including data presentation and timing. Conclusion: This method was acceptable to patients and secondary care physicians. Further work is needed to the improve GP responses and facilitate IRP.

scholarly journals Combating corruption in Singapore: a comparative analysis of two scandals

2020 ◽  
Vol 23 (1) ◽  
pp. 87-99
Author(s):  
Jon S.T. Quah
Keyword(s):  
Comparative Analysis ◽  
Design Methodology ◽  
Internal Controls ◽  
Public Official ◽  
Review Panel ◽  
Content Type ◽  
Audit System ◽  
Independent Review ◽  
Cover Up

PurposeThe purpose of this paper is to compare two corruption scandals in Singapore to illustrate how its government has dealt with these scandals and to discuss the implications for its anti-corruption strategy.Design/methodology/approachThis paper analyses the Teh Cheang Wan and Edwin Yeo scandals by relying on published official and press reports.FindingsBoth scandals resulted in adverse consequences for the offenders. Teh committed suicide on 14 December 1986 before he could be prosecuted for his bribery offences. Yeo was found guilty of criminal breach of trust and forgery and sentenced to 10 years' imprisonment. The Commission of Inquiry found that the Corrupt Practices Investigation Bureau (CPIB) was thorough in its investigations which confirmed that only Teh and no other minister or public official were implicated in the bribery offences. The Independent Review Panel appointed by the Prime Minister's Office to review the CPIB's internal controls following Yeo's offences recommended improvements to strengthen the CPIB's financial procedures and audit system. Singapore has succeeded in minimising corruption because its government did not cover-up the scandals but punished the guilty offenders and introduced measures to prevent their recurrence.Originality/valueThis paper will be useful for scholars, policymakers and anti-corruption practitioners interested in Singapore's anti-corruption strategy and how its government handles corruption scandals.

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