A Typical Path Model of Tracheobronchial Clearance of Inhaled Particles in Rats

2002 ◽  
Author(s):  
Edgar C. Kimmel ◽  
James E. Reboulet ◽  
Robert L. Carpenter
Keyword(s):  
Path Model ◽  
Inhaled Particles ◽  
Typical Path

A typical path model of tracheobronchial clearance of inhaled particles in rats

2001 ◽  
Vol 17 (5-10) ◽  
pp. 277-284 ◽  
Author(s):  
Edgar C Kimmel ◽  
James E Reboulet ◽  
Robert L Carpenter
Keyword(s):  
Path Model ◽  
Inhaled Particles ◽  
Typical Path

An integrated screening method for evaluating the pulmonary toxicity of inhaled particulates: Role of microscopic techniques in assessing pulmonary macrophage clearance functions

1990 ◽  
Vol 48 (3) ◽  
pp. 826-827
Author(s):  
David B. Warheit ◽  
Lena Achinko ◽  
Mark A. Hartsky
Keyword(s):  
Bronchoalveolar Lavage ◽  
Pulmonary Toxicity ◽  
Screening Method ◽  
Pulmonary Response ◽  
Inhaled Particles ◽  
Cytochemical Analysis ◽  
Pulmonary Macrophages ◽  
Integrated Screening

There is a great need for the development of a rapid and reliable bioassay to evaluate the pulmonary toxicity of inhaled particles. A number of methods have been proposed, including lung clearance studies, bronchoalveolar lavage analysis, and in vitro cytotoxicity tests. These methods are often limited in scope inasmuch as they measure only one dimension of the pulmonary response to inhaled, instilled or incubated dusts. Accordingly, a comprehensive approach to lung toxicity studies has been developed.To validate the method, rats were exposed for 6 hours or 3 days to various concentrations of either aerosolized alpha quartz silica (Si) or carbonyl iron (CI) particles. Cells and fluids from groups of sham and dust-exposed animals were recovered by bronchoalveolar lavage (BAL). Alkaline phosphatase, LDH and protein values were measured in BAL fluids at several time points postexposure. Cells were counted and evaluated for viability, as well as differential and cytochemical analysis. In addition, pulmonary macrophages (PM) were cultured and studied for morphology, chemotaxis, and phagocytosis by scanning electron microscopy.

Bidirectional Associations Between Self-Perceptions of Aging and Processing Speed Across 3 Years

GeroPsych ◽  
2017 ◽  
Vol 30 (2) ◽  
pp. 49-59 ◽  
Author(s):  
Anna L. Seidler ◽  
Julia K. Wolff
Keyword(s):  
Processing Speed ◽  
Personal Growth ◽  
Significant Loss ◽  
Path Model ◽  
Outcome Variable ◽  
Beneficial Effects ◽  
Self Perceptions ◽  
Chi Squared ◽  
Perceptions Of Aging ◽  
Bidirectional Associations

Abstract. Background: Previous studies point to a potential relationship between self-perceptions of aging (SPA) and cognitive performance. However, most of these studies are limited by their experimental design. Previous longitudinal studies looked solely at memory as an outcome variable without examining the directionality of effects. The present study examines the direction of effects between two domains of SPA (personal growth and physical losses) and processing speed (PS). Methods: The sample consists of 8,198 participants of the German Ageing Survey (DEAS), aged between 40 and 93 years. A cross-lagged path model was estimated to examine directions of relationships across 3 years via chi-squared difference tests for each domain of SPA. Results: In the unconstrained models, the effect of SPA domain personal growth in 2008 on PS in 2011 and vice versa were marginally significant. For SPA domain physical losses, the effect of SPA on PS was significant, whereas the other direction of the effect did not reach significance. However, the cross-lagged paths of both domains of SPA on PS and vice versa could be set equal without a significant loss of model fit. The resulting associations indicate a significant bidirectional relationship between both domains of SPA and PS. Discussion and conclusion: This study provides initial evidence that SPA can influence trajectories of cognitive decline and vice versa. The results emphasize the detrimental and beneficial effects that stereotypes can have on individuals and add further evidence to the theory of stereotype embodiment.

Passive Facebook Use and Depression

2020 ◽  
Vol 32 (4) ◽  
pp. 165-175 ◽  
Author(s):  
Leman Pınar Tosun ◽  
Ezgi Kaşdarma
Keyword(s):  
Social Comparisons ◽  
Path Model ◽  
The Other ◽  
Facebook Use ◽  
Psychological Mechanism ◽  
Model Fits

Abstract. In the current study we examined a psychological mechanism linking Facebook use to depression. A survey was conducted with 319 undergraduates about their passive Facebook use, their frequency of making upward social comparisons on Facebook, the emotions evoked through these comparisons, and their levels of depression. Half of the participants were given questions about the Facebook comparisons they made with their close friends, while the other half were given questions about the Facebook comparisons they made with acquaintances. Analysis of the whole sample revealed that upward Facebook comparison elicited assimilative emotions (inspiration, optimism, and admiration) more than contrastive emotions did (envy and resentment). A path model was developed in which passive use of Facebook predicted the frequency of making upward social comparisons, and, in turn, the frequency of making upward Facebook comparisons predicted depression through two routes: one through contrastive emotions and other through assimilative emotions. The results suggested that the model fits the data. As expected, the frequency of upward Facebook comparisons was associated with the increases in frequency of both contrastive and assimilative emotions, and the associations of these two types of emotions with depression were in opposite directions: Depression increased as the frequency of contrastive emotions increased, and it decreased as the frequency of assimilative emotions increased. The strength of the latter aforementioned association was stronger when the comparison targets were acquaintances rather than close friends.

The effects of cross training teams: A meta-analytic path model

2009 ◽  
Author(s):  
Kevin C. Stagl ◽  
Cameron Klein ◽  
Patrick J. Rosopa ◽  
Deborah DiazGranados ◽  
Eduardo Salas ◽  
...  
Keyword(s):  
Path Model ◽  
Cross Training

Interconnect Limits on Gigascale Integration (GSI)

1997 ◽  
Vol 473 ◽  
Author(s):  
J. A. Davis ◽  
J. D. Meindl
Keyword(s):  
Response Time ◽  
Length Distribution ◽  
Path Model ◽  
System Level ◽  
Wire Length ◽  
Clock Frequency ◽  
Gigascale Integration ◽  
Logic Network ◽  
Binary Switching ◽  
Quantitative Definition

ABSTRACTOpportunities for Gigascale Integration (GSI) are governed by a hierarchy of physical limits. The levels of this hierarchy have been codified as: 1) fundamental, 2) material, 3) device, 4) circuit and 5) system. Many key limits at all levels of the hierarchy can be displayed in the power, P, versus delay, td, plane and the reciprocal length squared, L-2, versus response time, τ, plane. Power, P, is the average power transfer during a binary switching transition and delay, td, is the time required for the transition. Length, L, is the distance traversed by an interconnect that joins two nodes on a chip and response time, τ, characterizes the corresponding interconnect circuit. At the system level of the hierarchy, quantitative definition of both the P versus td and the L-2 versus τ displays requires an estimate of the complete stochastic wiring distribution of a chip.Based on Rent's Rule, a well known empirical relationship between the number of signal input/output terminals on a block of logic and the number of gate circuits with the block, a rigorous derivation of a new complete stochastic wire length distribution for an on-chip random logic network is described. This distribution is compared to actual data for modern microprocessors and to previously described distributions. A methodology for estimating the complete wire length distribution for future GSI products is proposed. The new distribution is then used to enhance the critical path model that determines the maximum clock frequency of a chip; to derive a preliminary power dissipation model for a random logic network; and, to define an optimal architecture of a multilevel interconnect network that minimizes overall chip size. In essence, a new complete stochastic wiring distribution provides a generic basis for maximizing the value obtained from a multilevel interconnect technology.

FRAUD CONFIRMATION, CLIENT SATISFACTION AND CLIENT LOYALTY

2019 ◽  
Vol 1 (1) ◽  
pp. 39
Author(s):  
Ngurah Pandji Mertha Agung Durya
Keyword(s):  
Regression Analysis ◽  
Linear Regression ◽  
Client Satisfaction ◽  
Audit Quality ◽  
Hypothesis Test ◽  
Linear Regression Analysis ◽  
Quality Attributes ◽  
Path Model ◽  
Coefficient Of Determination ◽  
The Government

<p>This study aims to find evidence, the influence of Audit Quality Attributes, Client Satisfaction and Client Loyalty, which are moderated by Fraud Confirmation. The research was conducted at the BKM, a community-based organization, formed by the Government, through the <em>Kotaku</em> Program. The research used Regression statistical analysis and conducted a hypothesis test. Regression analysis used includes Simple Linear Regression Analysis, Multiple Regression Analysis, and MRA Regression Analysis, and Path Model Linear Regression Analysis. This study also pays attention to the calculation of the coefficient of determination to give an idea of the ability of the model in explaining the phenomenon of Client Satisfaction and Client Loyalty. The result that both partially and simultaneously, Audit Quality Attributes, Fraud Confirmation affected Client Satisfaction and Loyalty. The research also succeeded in proving that Client Satisfaction mediates the effect of Audit Quality Attributes on Client Loyalty, but failed to provide empirical evidence, that the Fraud Confirmation moderated the effect of Audit Quality Attributes on Client Satisfaction and Loyalty. Contribution to audit practices, where it is important to realize Client Satisfaction through Audit Quality Attributes and Fraud Confirmation, especially in situations where Fraud acts are suspected.</p>

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