Development of Methods to Isolate Recombinant Antibodies Against Prostate Cancer Antigens

2000 ◽  
Author(s):  
Myron N. Williams
Keyword(s):  
Prostate Cancer ◽  
Recombinant Antibodies ◽  
Cancer Antigens

scholarly journals Nanobodies: a tool to open new horizons in diagnosis and treatment of prostate cancer

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Maryam Hosseindokht ◽  
Hamid Bakherad ◽  
Hamed Zare
Keyword(s):  
Prostate Cancer ◽  
Early Detection ◽  
Cancer Cells ◽  
Target Therapy ◽  
Main Body ◽  
Prostate Cancer Cells ◽  
New Horizons ◽  
Large Size ◽  
Cancer Antigens ◽  
Specific Antigens

Abstract Background Prostate cancer is one of the most common cancers in men and its incidence has increased dramatically in the last decade. This increase in the detection of this type of cancer is based more on the detection of PSA or PSMA antigens as the most important specific antigens of this cancer, and this early detection has greatly helped in the more optimal treatment of patients. Main body Many methods have been proposed by researchers for early detection of prostate cancer, but most of the methods used today to detect this type of cancer have been using classical antibodies. Although classical antibodies are able to detect tumor cell markers, but instability, large size, costly and laborious production, and random immobility characteristics, causes many problems. Nanobodies or VHHs, which are derived from camel heavy chain antibodies, have special advantages and have eliminated the disadvantages of classical antibodies which makes them attractive to use in biosensors and cancer diagnostic kits. The research that has been done so far shows that the introduced nanobodies are created for the purpose of targeting, detecting and sensing prostate cancer cells with two main purposes. The first is the efficient identification of prostate cancer and the second is the elimination of cancer cells. Conclusion Research shows the use of specific nanobodies against prostate cancer antigens in the design of biosensors and target therapy will be very interesting. In this review article, these nanobodies are introduced and categorized based on their performance.

A new generation of monoclonal and recombinant antibodies against cell-adherent prostate specific membrane antigen for diagnostic and therapeutic targeting of prostate cancer

The Prostate ◽  
2006 ◽  
Vol 66 (13) ◽  
pp. 1359-1370 ◽  
Author(s):  
Ursula Elsässer-Beile ◽  
Philipp Wolf ◽  
Dorothee Gierschner ◽  
Patrick Bühler ◽  
Wolfgang Schultze-Seemann ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Recombinant Antibodies ◽  
Prostate Specific Membrane Antigen ◽  
Therapeutic Targeting ◽  
New Generation ◽  
Specific Membrane

Identification of prostate cancer antigens by automated high-throughput filter immunoscreening

2008 ◽  
Vol 330 (1-2) ◽  
pp. 12-23 ◽  
Author(s):  
Lene Alsøe ◽  
John Erik Stacy ◽  
Alexander Fosså ◽  
Steinar Funderud ◽  
Ole Henrik Brekke ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
High Throughput ◽  
Cancer Antigens

Sigmoidoscopic findings following radiation for prostate cancer

2001 ◽  
Vol 120 (5) ◽  
pp. A284-A284
Author(s):  
T BOLIN ◽  
A KNEEBONE ◽  
T LARSSON
Keyword(s):  
Prostate Cancer

1625: Neuroligin 4 ISOFORM Y: A Novel Marker for Prostate Cancer

2007 ◽  
Vol 177 (4S) ◽  
pp. 538-539
Author(s):  
Joseph F. Pazona ◽  
C. Shad Thaxton ◽  
Neema Navai ◽  
Brian T. Helfand ◽  
Lee C. Zhao ◽  
...  
Keyword(s):  
Prostate Cancer

232: Natural History of Treated Biochemical Recurrence after Radical Prostatectomy for Prostate Cancer

2007 ◽  
Vol 177 (4S) ◽  
pp. 77-78
Author(s):  
Christopher R. Porter ◽  
Jochen Walz ◽  
Andrea Gallina ◽  
Claudio Jeldres ◽  
Koichi Kodama ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Natural History ◽  
Biochemical Recurrence ◽  
History Of

466: Age is an Independent Predictor of Bone Metastasis at Prostate Cancer Diagnosis

2007 ◽  
Vol 177 (4S) ◽  
pp. 156-156
Author(s):  
Andrea Salonia ◽  
Pierre I. Karakiewicz ◽  
Andrea Gallina ◽  
Alberto Briganti ◽  
Tommaso C. Camerata ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Bone Metastasis ◽  
Cancer Diagnosis ◽  
Independent Predictor ◽  
Prostate Cancer Diagnosis
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