Combined Effects of Hyperbaric Oxygen and Antimicrobials in a Model of Gas Gangrene.

1992 ◽  
Author(s):  
K. H. Muhvich ◽  
L. H. Anderson ◽  
W. J. Mehm
Keyword(s):  
Hyperbaric Oxygen ◽  
Gas Gangrene ◽  
Combined Effects

Hyperbaric oxygen in anaerobic infection of the mediastinum

1975 ◽  
Vol 89 (11) ◽  
pp. 1147-1150 ◽  
Author(s):  
I. Monies-Chass ◽  
H. Z. Joachims ◽  
M. M. Altman
Keyword(s):  
Hyperbaric Oxygen ◽  
Anaerobic Bacteria ◽  
Gas Gangrene ◽  
Causative Organism ◽  
Anaerobic Infection ◽  
Road Accidents ◽  
War Wounds ◽  
Broken Bones ◽  
Surgical Measures ◽  
Oxygenation Level

AbstractIN the last decade hyperbaric oxygen has been recognized as an important therapeutic tool in a variety of instances in which either destruction of anaerobic bacteria is urgent or an improvement in the oxygenation level is mandatory. We have usede it successfully in a case of mediastinal anaerobic infection (gas gangrene) after medical and surgical measures had failed to eradicate the disease.The causative organism of gas gangrene, Clostridium perfringens (Welchii), is widely distributed. It may be cultured from the soil, house dust, human skin and faeces, etc. For this reason infection with Clostridium is practically inevitable whenever suitable conditions arise. As an anaerobic bacterium Clostridium Welchii multiplies readily in damaged tissues without cantact with the air and devoid of a normal blood supply. This occurs especially in road accidents and war wounds in which broken bones and crushed muscles provide a suitable medium for the infection (Altmeier 1965). Sometimes this infection can occur too after abdominal or gynaecological operations (Hitchcock, 1965).We present here a case of mediastinal gas gangrene which was caused by perforation of the oesophagus by a swallowed foreign body.

HYPERBARIC OXYGEN USED IN THE TREATMENT OF GAS GANGRENE

1967 ◽  
Vol 2 (22) ◽  
pp. 991-993
Author(s):  
G. J. A. Bayliss ◽  
Cecil Cass
Keyword(s):  
Hyperbaric Oxygen ◽  
Gas Gangrene

Hyperbaric oxygen used in the treatment of gas gangrene in a dog

1976 ◽  
Vol 17 (11) ◽  
pp. 759-764 ◽  
Author(s):  
N. A. COOPER ◽  
I. P. UNSWORTH ◽  
D. M. TURNER ◽  
J. E. ILKIW
Keyword(s):  
Hyperbaric Oxygen ◽  
Gas Gangrene

Hyperbaric Oxygen Therapy in the Treatment of Gas Gangrene

1970 ◽  
Vol 56 (1) ◽  
pp. 26-38
Author(s):  
John P. Beavis ◽  
James Watt
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Gas Gangrene ◽  
Systemic Effects ◽  
War Injuries ◽  
Muscle Biopsies

AbstractGas gangrene will continue to complicate contaminated war injuries. Local and systemic effects of exotoxins are described and an aggressive regimen of therapy is proposed. The beneficial results of such treatment are reported and the respective merits of hyperbaric oxygen, antibiotics, debridement and cortisone are debated. The histological appearances of muscle biopsies obtained at initial debridement are discussed.

scholarly journals Gas Gangrene and Hyperbaric Oxygen

BMJ ◽  
1972 ◽  
Vol 4 (5833) ◽  
pp. 174-175
Author(s):  
D. J. D. Perrins
Keyword(s):  
Hyperbaric Oxygen ◽  
Gas Gangrene

scholarly journals Gas gangrene and hyperbaric oxygen.

BMJ ◽  
1972 ◽  
Vol 4 (5831) ◽  
pp. 47-47
Author(s):  
T T Irvin
Keyword(s):  
Hyperbaric Oxygen ◽  
Gas Gangrene
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