The Critical Role of Real-Time Downhole Telemetry for the Success of Conformance Control Operations with Extreme Permeability Contrast

The Effects of Real-Time Interactive Multimedia Teleradiology System

BioMed Research International ◽

10.1155/2016/4126841 ◽

2016 ◽

Vol 2016 ◽

pp. 1-9 ◽

Cited By ~ 3

Author(s):

Lilac Al-Safadi

Keyword(s):

Real Time ◽

Interactive Multimedia ◽

Point Of Care ◽

Critical Role ◽

Web Based ◽

Teleradiology System ◽

Multimedia Technologies ◽

Referring Physicians ◽

Improving Patient Care

This study describes the design of a real-time interactive multimedia teleradiology system and assesses how the system is used by referring physicians in point-of-care situations and supports or hinders aspects of physician-radiologist interaction. We developed a real-time multimedia teleradiology management system that automates the transfer of images and radiologists’ reports and surveyed physicians to triangulate the findings and to verify the realism and results of the experiment. The web-based survey was delivered to 150 physicians from a range of specialties. The survey was completed by 72% of physicians. Data showed a correlation between rich interactivity, satisfaction, and effectiveness. The results of our experiments suggest that real-time multimedia teleradiology systems are valued by referring physicians and may have the potential for enhancing their practice and improving patient care and highlight the critical role of multimedia technologies to provide real-time multimode interactivity in current medical care.

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Atg16L1 as a Novel Biomarker and Autophagy Gene for Diabetic Retinopathy

Journal of Diabetes Research ◽

10.1155/2021/5398645 ◽

2021 ◽

Vol 2021 ◽

pp. 1-11

Author(s):

Xinxiao Gao ◽

Yunhui Du ◽

Wayne Bond Lau ◽

Yu Li ◽

Siquan Zhu ◽

...

Keyword(s):

Diabetic Retinopathy ◽

Real Time ◽

Potential Role ◽

Critical Role ◽

Differentially Expressed ◽

Chain Reactions ◽

Polymerase Chain Reactions ◽

Polymerase Chain ◽

Microarray Analyses

Objective. Accumulating evidence suggests the critical role of autophagy in the pathogenesis of diabetic retinopathy (DR). In the current study, we aim to identify autophagy genes involved in DR via microarray analyses. Methods. Gene microarrays were performed to identify differentially expressed lncRNAs/mRNAs between normal and DR retinas. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses of lncRNA-coexpressed mRNAs were used to determine the related pathological pathways and biological modules. Real-time polymerase chain reactions (PCR) were conducted to validate the microarray analyses. Results. A total of 2474 significantly dysregulated lncRNAs and 959 differentially expressed mRNAs were identified in the retina of DR. Based upon Signalnet analysis, Bcl2, Gabarapl2, Atg4c, and Atg16L1 participated the process of cell death in DR. Moreover, real-time PCR revealed significant upregulation of Atg16L1. Conclusion. This study indicated the importance and potential role of Atg16L1, one of the autophagy genes, as a biomarker in DR development and progression.

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The Neural Basis of Predictive Pursuit

10.1101/694604 ◽

2019 ◽

Cited By ~ 2

Author(s):

Seng Bum Michael Yoo ◽

Jiaxin Cindy Tu ◽

Steven T. Piantadosi ◽

Benjamin Yost Hayden

Keyword(s):

Anterior Cingulate Cortex ◽

Real Time ◽

Critical Role ◽

Cingulate Cortex ◽

Explicit Representation ◽

Anterior Cingulate ◽

Neural Basis ◽

Dorsal Anterior Cingulate Cortex ◽

The Brain

ABSTRACTIt remains unclear how and to what extent non-human animals make demanding on-the-fly predictions during pursuit. We studied this problem in a novel laboratory pursuit task that incentivizes prediction of future prey positions. We trained three macaques to perform joystick-controlled pursuit of prey that followed intelligent escape algorithms. Subjects reliably aimed towards the prey’s likely future positions, indicating that they generate internal predictions and use those predictions to guide behavior. We then developed a generative model that explains real-time pursuit trajectories and showed that our subjects use prey position, velocity, and acceleration to make predictions. We identified neurons in the dorsal anterior cingulate cortex (dACC) whose responses track these three variables. These neurons multiplexed prediction-related variables with a distinct and explicit representation of the prey’s future position. Our results provide a clear demonstration that the brain can explicitly represent future predictions and highlight the critical role of anterior cingulate cortex for future-oriented cognition.One-sentence summaryIn a dynamic pursuit environment, monkeys actively predict future prey positions and dACC neurons encode these future positions.

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The critical role of direct observation in entrustment decisions

Canadian Medical Education Journal ◽

10.36834/cmej.72040 ◽

2021 ◽

Author(s):

Matthew Sibbald ◽

Muqtasid Mansoor ◽

Michael Tsang ◽

Sarah Blissett ◽

Geoffrey Norman

Keyword(s):

Real Time ◽

Direct Observation ◽

Postgraduate Training ◽

Critical Role ◽

Reliability And Validity ◽

Consequential Validity ◽

Systematic Direct Observation ◽

Objective Structured Clinical Exam ◽

Past Experiences

Background: Entrustment decisions may be retrospective (based on past experiences with a trainee) or real-time (based on direct observation). We investigated judgments of entrustment based on assessor prior knowledge of candidates and based on systematic direct observation, conducted in an objective structured clinical exam (OSCE). Methods: Sixteen faculty examiners provided 287 retrospective and real-time entrustment ratings of 16 cardiology trainees during OSCE stations in 2019 and 2020. Reliability and validity of these ratings were assessed by comparing correlations across stations as a measure of reliability, differences across postgraduate years as an index of construct validity, correlation to standardized in-training exam (ITE) as a measure of criterion validity, and reclassification of entrustment as a measure of consequential validity. Results: Both retrospective and real-time assessments were highly reliable (all intra-class correlations >0.86). Both increased with year of postgraduate training. Real-time entrustment ratings were significantly correlated with standardized ITE scores; retrospective ratings were not. Real-time ratings explained 37% (2019) and 46% (2020) of variance in examination scores vs. 21% (2019) and 7% (2020) for retrospective ratings. Direct observation resulted in a different level of entrustment compared with retrospective ratings in 44% of cases (p = <0.001). Conclusions: Ratings based on direct observation made unique contributions to entrustment decisions.

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Real-time monitoring of hydrophobic aggregation reveals a critical role of cooperativity in hydrophobic effect

Nature Communications ◽

10.1038/ncomms15639 ◽

2017 ◽

Vol 8 (1) ◽

Cited By ~ 27

Author(s):

Liguo Jiang ◽

Siqin Cao ◽

Peter Pak-Hang Cheung ◽

Xiaoyan Zheng ◽

Chris Wai Tung Leung ◽

...

Keyword(s):

Real Time ◽

Critical Role ◽

Hydrophobic Effect ◽

Real Time Monitoring ◽

Hydrophobic Aggregation

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Prevalence of HPV 16 and HPV 18 in cervical cancer in Minia Governorate

10.51429/ejmm29408 ◽

2020 ◽

Vol EJMM29 (4) ◽

pp. 57-63

Author(s):

Mohammed S. Mohammed ◽

Ahmed S. Sand ◽

Noha A. Hassuna

Keyword(s):

Cervical Cancer ◽

Real Time ◽

Real Time Pcr ◽

Critical Role ◽

Hpv Infection ◽

Hpv Dna ◽

Contraceptive Usage ◽

Significant Difference ◽

Histopathological Results

Background: Human Papilloma virus (HPV) have a critical role in cervical cancer especially type 16 and 18 and great efforts were done to determine the role of HPV in cervical cancer. Objective: The objective of this work is evaluation of the prevalence of cervical cancer and determination of the role of HPV in cervical cancer, in Minia Governorate. Methodology: Colposcopic-directed biopsy was done for one hundred females by colposcopist. One hundred women were included in this study for detection of HPV infection by histopathology, real time PCR and sequencing. One hundred biopsies were subjected to analysis for detection of HPV types 16 and 18 by histopathology, real time PCR and sequencing. Results and conclusion: Our histopathological results revealed that 15% of samples were positive for HPV and by HPV DNA real time PCR, 14% were positive. Our study reported that the infection was single in 9% and mixed in 5% and HPV type 16 was higher than type 18. The age range across the sample was 18–55 years with a median age of 35 years. The women patients with subtype 18 had the highest median age. Contraceptive usage had a statistically significant difference especially using OC.

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Frequency of Pathogenic Paediatric Bacterial Meningitis in Mozambique: The Critical Role of Multiplex Real-Time Polymerase Chain Reaction to Estimate the Burden of Disease

PLoS ONE ◽

10.1371/journal.pone.0138249 ◽

2015 ◽

Vol 10 (9) ◽

pp. e0138249 ◽

Cited By ~ 11

Author(s):

Aquino Albino Nhantumbo ◽

Vlademir Vicente Cantarelli ◽

Juliana Caireão ◽

Alcides Moniz Munguambe ◽

Charlotte Elizabeth Comé ◽

...

Keyword(s):

Polymerase Chain Reaction ◽

Bacterial Meningitis ◽

Real Time ◽

Burden Of Disease ◽

Critical Role ◽

Chain Reaction ◽

Polymerase Chain

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The Role of the SLP in Autism Spectrum Disorder Screening and Assessment

Perspectives on Language Learning and Education ◽

10.1044/lle15.2.50 ◽

2008 ◽

Vol 15 (2) ◽

pp. 50-59 ◽

Cited By ~ 1

Author(s):

Amy Philofsky

Keyword(s):

Language Development ◽

Critical Role ◽

Children With Autism ◽

Autism Spectrum ◽

Children With Asd ◽

Prevalence Estimates ◽

Notable Increase ◽

Screening Assessment ◽

Critical Components

AbstractRecent prevalence estimates for autism have been alarming as a function of the notable increase. Speech-language pathologists play a critical role in screening, assessment and intervention for children with autism. This article reviews signs that may be indicative of autism at different stages of language development, and discusses the importance of several psychometric properties—sensitivity and specificity—in utilizing screening measures for children with autism. Critical components of assessment for children with autism are reviewed. This article concludes with examples of intervention targets for children with ASD at various levels of language development.

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