Vitamin D status in Mexican children 1 to 11 years of age: an update from the Ensanut 2018-19

2021 ◽  
Vol 63 (3 May-Jun) ◽  
pp. 382-393
Author(s):  
Mario E Flores ◽  
Marta Rivera-Pasquel ◽  
Andrys Valdez-Sánchez ◽  
Vanessa De la Cruz-Góngora ◽  
Alejandra Contreras-Manzano ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Dairy Products ◽  
The Body ◽  
School Age Children ◽  
School Age ◽  
Vitamin D Status ◽  
Serum Samples ◽  
Related Factors ◽  
Mexican Children

Objective. To evaluate vitamin D status and deficiency in Mexican children and related factors, with updated data from a representative national survey. Materials and methods. Data and serum samples of child participants were collected in the Ensanut 2018-19. The measurement 25-(OH)-D was obtained through chemiluminescence. Height and weight, as well as dietary information, were measured using a semi-quan­titative food frequency questionnaire and sociodemographic information. Results. Data of 4 691 children aged 1-11 years were analyzed. Vitamin D deficiency (25-OH-D<50 nmol/L) was found in 27.3% of pre-school-age children and 17.2% of school-age children, and was positively associated with the body mass index (BMI). Main dietary sources were milk, eggs and dairy products, which in combination provided >70% of vitamin D intake. Conclusions. Vitamin D deficiency is important in Mexican children. Actions and programs to fight this deficiency are required.

scholarly journals Vitamin D deficiency is common and is associated with overweight in Mexican children aged 1–11 years

2017 ◽  
Vol 20 (10) ◽  
pp. 1807-1815 ◽  
Author(s):  
Amada Flores ◽  
Mario Flores ◽  
Nayeli Macias ◽  
Lucía Hernández-Barrera ◽  
Marta Rivera ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
School Children ◽  
School Age Children ◽  
School Age ◽  
Nutrition Survey ◽  
Hydroxyvitamin D ◽  
Vitamin D Intake ◽  
Mexican Children ◽  
25 Hydroxyvitamin D

AbstractObjectiveTo assess vitamin D dietary sources, intake and 25-hydroxyvitamin D status and their association with individual and sociodemographic characteristics in Mexican children.DesignData obtained from 2695 children aged 1–11 years from the Mexican National Health and Nutrition Survey (2012) were analysed. Diet was assessed by a 141-item FFQ. 25-Hydroxyvitamin D was measured by a chemiluminescent assay.ResultsMean vitamin D intake was 3·38 (se 0·09) µg/d (135·2 (se 3·6) IU/d) among pre-school children and 2·85 (se 0·06) µg/d (114·0 (se 2·4) IU/d) in school-age children. Milk accounted for 64·4 % of vitamin D intake in pre-school children and 54·7 % in school-age children. Vitamin D deficiency (serum 25-hydroxyvitamin D<50 nmol/l) was 25·9 % in pre-schoolers and 36·6 % in school-age children. Overweight/obese school-age children had a higher risk of vitamin D deficiency compared with normal-weight children (OR=2·23; 95 % CI 1·36, 3·66; P<0·05).ConclusionsVitamin D intakes are low in Mexican children, and milk is the main source of the vitamin. Vitamin D deficiency is common and associated with overweight in school-age children.

scholarly journals Vitamin D Deficiency in School-Age Children Is Associated with Sociodemographic and Lifestyle Factors

2015 ◽  
Vol 145 (4) ◽  
pp. 791-798 ◽  
Author(s):  
Trudy Voortman ◽  
Edith H van den Hooven ◽  
Annemieke C Heijboer ◽  
Albert Hofman ◽  
Vincent WV Jaddoe ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Lifestyle Factors ◽  
School Age Children ◽  
School Age

P146 Estimation of vitamin D deficiency in healthy school-age children: current status in Italy

2018 ◽  
Vol 50 (4) ◽  
pp. e409
Author(s):  
T. Galeazzi ◽  
C. Monachesi ◽  
A.K. Verma ◽  
M. Brugia ◽  
L. Marinelli ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Current Status ◽  
School Age Children ◽  
School Age

scholarly journals Vitamin D for secondary prevention of acute wheeze attacks in preschool and school-age children

Thorax ◽  
2019 ◽  
Vol 74 (10) ◽  
pp. 977-985 ◽  
Author(s):  
Christos Stefanidis ◽  
Adrian R Martineau ◽  
Chinedu Nwokoro ◽  
Christopher J Griffiths ◽  
Andrew Bush
Keyword(s):  
Vitamin D ◽  
Secondary Prevention ◽  
Vitamin D Supplementation ◽  
Small Sample ◽  
Preschool Age ◽  
School Age Children ◽  
School Age ◽  
Vitamin D Status ◽  
Increased Risk ◽  
Tract Infections

IntroductionVitamin D is best known for its role in bone health; however, the discovery of the vitamin D receptor and the expression of the gene encoding the vitamin D 1α-hydroxylase (CYP27B1) enzyme in a wide variety of tissues including immune cells and respiratory epithelium has led to the discovery of potential roles for vitamin D in the prevention of acute wheeze.MethodsWe review here the literature concerning the relationships between circulating 25-hydroxyvitamin D (25(OH)D) concentration and secondary prevention of acute wheeze attacks in preschool and school-age children.ResultsEpidemiological data suggest that vitamin D insufficiency (25(OH)D <75 nmol/L) is highly prevalent in preschool and school-age children with wheeze. Preschool age children with a history of wheeze attacks and circulating 25(OH)D <75 nmol/L are at increased risk and frequency of future acute wheeze. However, no consistent association between low vitamin D status and risk of acute wheeze is reported in school-age children. Seven randomised controlled trials (RCTs) with relatively small sample sizes (30–430) and variable quality showed inconsistent results regarding the effect of oral vitamin D supplementation during childhood on the risk of asthma attacks, asthma symptom control, inhaled corticosteroid requirements, spirometry and unscheduled healthcare attendances for wheeze. A RCT showed that vitamin D supplementation had no effect on the frequency of unplanned healthcare attendances due to acute wheeze in 22 preschool children.DiscussionAn evidence-based recommendation for the use of vitamin D as a preventive therapy for wheeze attacks cannot be made until results of further trials are available. The assessment of circulating 25(OH)D concentration and the optimisation of vitamin D status to prevent acute respiratory tract infections, and to maintain skeletal and general health in preschool and school-age children with acute wheeze is worthwhile in its own right, but whether this will reduce the risk of acute wheeze attacks is unclear.

Effects of Vitamin D Status on Inflammatory Markers in Obese Subjects: A Systematic Review

2020 ◽  
Vol 16 (3) ◽  
pp. 268-275
Author(s):  
Geórgia R.R. de Alencar ◽  
Lailton da Silva Freire ◽  
Beatriz de Mello Pereira ◽  
Verbena R. da Silva ◽  
Aline C. Holanda ◽  
...  
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Inflammatory Markers ◽  
Observational Studies ◽  
The Body ◽  
Low Grade ◽  
Vitamin D Status ◽  
Obese Subjects ◽  
High Concentrations

Background: Recent studies have demonstrated the role of micronutrients in the manifestation of comorbidities associated with obesity. Vitamin D deficiency, in particular, appears to be associated with increased levels of inflammatory markers, which may lead to chronic low-grade inflammation, elevating the risk of chronic diseases such as diabetes, metabolic syndrome, and cardiovascular disease. The objective of this study was to perform a systematic review of observational studies conducted to investigate the effect of vitamin D deficiency on inflammatory markers in obese subjects. Methodology: This systematic review was conducted in accordance with the “STROBE” and PRISMA recommendations. Observational studies that evaluated the effect of vitamin D status on inflammatory markers in obese subjects were selected and reviewed. Searches were conducted in the PubMed, SciVerse Scopus, and Web of Science databases from February 21 to 22, 2018. Results: After the selection and removal of duplicate articles, 10 eligible articles were identified. Results from eight observational studies showed an association between vitamin D deficiency or insufficiency in the body and increased concentrations of inflammatory markers in obese individuals. On the other hand, two of the studies did not demonstrate any correlation. With regard to the inflammatory markers evaluated, eight studies showed high concentrations of ultra-sensitive C-reactive protein, five studies found an increase in interleukin-6 concentrations, and two studies noted increased levels of tumor necrosis factor. Conclusion: The data presented in this systematic review provide evidence of the association between vitamin D deficiency and increased inflammation in obesity.

scholarly journals Calcium absorption and vitamin D status in school age children

2009 ◽  
Vol 23 (S1) ◽  
Author(s):  
Steven A Abrams ◽  
Penni D Hicks ◽  
Keli M Hawthorne
Keyword(s):  
Vitamin D ◽  
Calcium Absorption ◽  
School Age Children ◽  
School Age ◽  
Vitamin D Status

scholarly journals Summary Outcomes of the ODIN Project on Food Fortification for Vitamin D Deficiency Prevention

2018 ◽  
Vol 15 (11) ◽  
pp. 2342 ◽  
Author(s):  
Mairead Kiely ◽  
Kevin Cashman
Keyword(s):  
Vitamin D ◽  
Ethnic Minority ◽  
Vitamin D Deficiency ◽  
White Women ◽  
Life Stage ◽  
Scale Up ◽  
School Age Children ◽  
Vitamin D Status ◽  
White Children ◽  
Technological Platform

Food-based solutions for optimal vitamin D nutrition and health through the life cycle (ODIN) was a cross-disciplinary, collaborative project, including 30 partners from 19 countries, which aimed to develop evidence-based solutions to prevent low vitamin D status (25-hydroxyvitamin D (25(OH)D) < 30 nmol/L) using a food-first approach. This paper provides a summary overview of some of the important ODIN outcomes and outlines some outstanding data requirements. In a study of almost 56,000 individuals, the first internationally standardised dataset of vitamin D status showed that 13% of EU residents overall, across a latitude gradient of 35° N to 69° N, had serum 25(OH)D < 30 nmol/L and 40% were < 50 nmol/L. The risk of low vitamin D status was several-fold higher among persons of ethnic minority. However, additional data from quality bio-banked sera would be required to improve these estimates. To address the question of dietary requirements for vitamin D among under-researched life-stage and population groups, four dose-response RCTs conducted in Northern Europe showed that vitamin D3 intakes of 8 and 13 μg/day prevented 25(OH)D decreasing below 30 nmol/L in white children and adolescents and 20 and 30 μg/day, respectively, achieved ≥50 nmol/L. Among white women during pregnancy, 30 μg/day is required to prevent umbilical cord 25(OH)D, representing new-born vitamin D status, below 25 nmol/L. While 8 μg/day protected white women in Finland at the 30 nmol/L cut-off, 18 μg/day was needed by women of East African descent to prevent 25(OH)D decreasing below 30 nmol/L during wintertime. Replicate RCTs are needed in young children <5 years and in school-age children, teens and pregnant women of ethnic minority. Using a series of food production studies, food-based RCTs and dietary modelling experiments, ODIN research shows that diverse fortification strategies could safely increase population intakes and prevent low vitamin D status. Building on this solid technological platform, implementation research is now warranted to scale up interventions in real-world settings to eradicate vitamin D deficiency.

Vitamin D Deficiency Associated With Increased Incidence of Gastrointestinal and Ear Infections in School-age Children

2013 ◽  
Vol 32 (6) ◽  
pp. 585-593 ◽  
Author(s):  
Kathryn A. Thornton ◽  
Constanza Marín ◽  
Mercedes Mora-Plazas ◽  
Eduardo Villamor
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
School Age Children ◽  
School Age ◽  
Ear Infections

Vitamin D Deficiency and Indicators of Increased Adiposity in School-age Children: A Prospective Study

Epidemiology ◽  
2011 ◽  
Vol 22 ◽  
pp. S287
Author(s):  
Diane Gilbert-Diamond ◽  
Ana Baylin ◽  
Mercedes Mora-Plazas ◽  
Constanza Marin ◽  
Michael Hughes ◽  
...  
Keyword(s):  
Vitamin D ◽  
Prospective Study ◽  
Vitamin D Deficiency ◽  
School Age Children ◽  
School Age ◽  
A Prospective Study

scholarly journals A Critical Appraisal of Strategies to Optimize Vitamin D Status in Germany, a Population with a Western Diet

Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2682 ◽  
Author(s):  
Roman Saternus ◽  
Thomas Vogt ◽  
Jörg Reichrath
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Biological Effects ◽  
Western Diet ◽  
The Body ◽  
Biologically Active ◽  
German Population ◽  
Vitamin D Metabolites ◽  
Vitamin D Status ◽  
Dihydroxyvitamin D

During the last decade, our scientific knowledge of the pleiotropic biological effects of vitamin D metabolites and their relevance to human health has expanded widely. Beyond the well-known key role of vitamin D in calcium homeostasis and bone health, it has been shown that vitamin D deficiency is associated with a broad variety of independent diseases, including several types of cancer, and with increased overall mortality. Moreover, recent findings have demonstrated biological effects of the vitamin D endocrine system that are not mediated via activation of the classical nuclear vitamin D receptor (VDR) by binding with high affinity to its corresponding ligand, the biologically active vitamin D metabolite 1,25-dihydroxyvitamin D (1,25(OH)2D). In contrast, many of these new biological effects of vitamin D compounds, including regulation of the circadian clock and many metabolic functions, are mediated by other vitamin D metabolites, including 20-hydroxyvitamin D and 20,23-dihydroxyvitamin D, and involve their binding to the aryl hydrocarbon receptor (AhR) and retinoid-orphan receptor (ROR). In most populations, including the German population, UVB-induced cutaneous vitamin D production is the main source for fulfilling the human body’s requirements of vitamin D. However, this causes a dilemma because solar or artificial UVR exposure is associated with skin cancer risk. In addition to UVB-induced vitamin D production in skin, in humans, there are two other possible sources of vitamin D: from diet and supplements. However, only a few natural foods contain substantial amounts of vitamin D, and in most populations, the dietary source of vitamin D cannot fulfill the body´s requirements. Because an increasing body of evidence has convincingly demonstrated that vitamin D deficiency is very common worldwide, it is the aim of this paper to (i) give an update of the vitamin D status in a population with a western diet, namely, the German population, and to (ii) develop strategies to optimize the vitamin D supply that consider both the advantages as well as the disadvantages/risks of different approaches, including increasing vitamin D status by dietary intake, by supplements, or by UVB-induced cutaneous synthesis of vitamin D.

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