Local Vitamin-C Injection Reduced Tendon Adhesion in a Chicken Model of Flexor Digitorum Profundus Tendon Injury

2013 ◽  
Vol 95 (7) ◽  
pp. e41 ◽  
Author(s):  
Leung-Kim Hung ◽  
Sai-Chuen Fu ◽  
Yuk-Wa Lee ◽  
Tsui-Yu Mok ◽  
Kai-Ming Chan
Keyword(s):  
Vitamin C ◽  
Tendon Injury ◽  
Flexor Digitorum Profundus ◽  
Flexor Digitorum ◽  
Flexor Digitorum Profundus Tendon ◽  
Chicken Model

Patterns of Cellular Activation after Tendon Injury

1996 ◽  
Vol 21 (6) ◽  
pp. 813-820 ◽  
Author(s):  
U. KHAN ◽  
J. C. W. EDWARDS ◽  
D. A. McGROUTHER
Keyword(s):  
Flexor Tendon ◽  
Rabbit Model ◽  
Early Period ◽  
Tendon Injury ◽  
Flexor Digitorum Profundus ◽  
Cellular Activation ◽  
Relative Response ◽  
Tendon Surgery ◽  
Flexor Digitorum ◽  
Flexor Digitorum Profundus Tendon

Mechanisms which lead to disabling adhesions following flexor tendon surgery of the hand were investigated in a rabbit model which was used to assess the relative response of the cells of the synovial sheath, epitenon and the endotenon to injury. A transverse laceration, cutting through 50% of the tendon, was made just outside the synovial sheath on the flexor aspect of the flexor digitorum profundus tendon. The synovial sheath was preserved intact. Using monoclonal antibodies for localizing specific inflammatory markers, we were able to follow the response and activity of the synovial sheath, epitenon and endotenon with respect to these markers at various times after surgery. Our findings suggest that the synovial sheath and the epitenon are relatively more reactive in the early period after injury, as judged by a range of inflammatory indices with the notable exception of the expression of the potent neovascularizing agent, basic fibroblast growth factor (bFGF).

scholarly journals Closed Partial Flexor Digitorum Profundus Rupture: An Unusual Cause of Pediatric Trigger Finger

Hand ◽  
2016 ◽  
Vol 12 (5) ◽  
pp. NP92-NP94
Author(s):  
Shane R. Jackson ◽  
Meily Tan ◽  
Kim O. Taylor
Keyword(s):  
Tendon Injury ◽  
Trigger Finger ◽  
Flexor Digitorum Profundus ◽  
Flexor Tendon Injury ◽  
Normal Tendon ◽  
Operative Exploration ◽  
A2 Pulley ◽  
Flexor Digitorum ◽  
Flexor Digitorum Profundus Tendon ◽  
Tendon Laceration

Background: Trigger finger is a common condition, causing impaired gliding of the digital flexor tendons. Chronic inflammation is the usual cause, but acute trigger finger following partial tendon laceration has also been described. Methods: We describe the case of a four year old girl who presented with inability to flex her index finger. Operative exploration revealed a closed partial rupture of the flexor digitorum profundus tendon, catching on the A2 pulley and preventing normal tendon gliding. Results: Excision of the damaged section of tendon allowed normal gliding motion, and once the wound had healed the patient regained full painless motion. Conclusion: Acute trigger finger caused by partial flexor tendon injury is an uncommon but well-documented presentation. Surgical exploration not only confirms the diagnosis, but allows for excision of the damaged segment to return normal movement without compromising strength.

ADHESION FORMATION AFTER FLEXOR TENDON REPAIR: COMPARISON OF TWO- AND FOUR-STRAND REPAIR WITHOUT EPITENDINOUS SUTURE

Hand Surgery ◽  
2005 ◽  
Vol 10 (02n03) ◽  
pp. 193-197 ◽  
Author(s):  
Margaret J. Strick ◽  
Susan L. Filan ◽  
Mark Hile ◽  
Catriona McKenzie ◽  
William R. Walsh ◽  
...  
Keyword(s):  
Broiler Chickens ◽  
Adhesion Formation ◽  
Biomechanical Testing ◽  
Tendon Repair ◽  
Flexor Digitorum Profundus ◽  
Significant Difference ◽  
Histological Data ◽  
Flexor Digitorum ◽  
Flexor Digitorum Profundus Tendon ◽  
Chicken Model

Increased handling, increased bulk at the repair site and an increase in external suture material may affect adhesion formation and gliding after tendon repair. A previous study1 showed no significant difference in biomechanical or histopathological measurement of adhesion formation in two- and four-strand repairs combined with an epitendinous suture in the chicken model. In the present study, the flexor digitorum profundus tendon of the middle toe of 47 broiler chickens was cut and repaired with either a single (two-strand) or double (four-strand) modified Kessler core suture without epitendinous suture and immobilised for four weeks. Adhesion formation was measured by biomechanical testing or quantitative and qualitative histopathology. Biomechanical and histological data showed no differences between two- and four-strand repairs. Results did not differ from the previous study which used an epitendinous suture. Adhesion formation is not necessarily increased when multi-strand techniques are used, nor by the placement of an epitendinous suture if care is taken with surgical technique. Individual healing response introduces more variability than an increase in tendon handling by an experienced surgeon.

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