The Effect of Thrombin Activation of Platelet-Rich Plasma on Demineralized Bone Matrix Osteoinductivity

2009 ◽  
Vol 91 (6) ◽  
pp. 1459-1470 ◽  
Author(s):  
Bo Han ◽  
Jennifer Woodell-May ◽  
Michael Ponticiello ◽  
Zhi Yang ◽  
Marcel Nimni
Keyword(s):  
Demineralized Bone Matrix ◽  
Platelet Rich Plasma ◽  
Bone Matrix ◽  
Thrombin Activation ◽  
Demineralized Bone

Platelet-Rich Plasma Inhibits Demineralized Bone Matrix-Induced Bone Formation in Nude Mice

2007 ◽  
Vol 89 (1) ◽  
pp. 139-147 ◽  
Author(s):  
Don M. Ranly ◽  
Barbara D. Boyan ◽  
Zvi Schwartz ◽  
Christoph H. Lohmann ◽  
Domenico Andreacchio
Keyword(s):  
Bone Formation ◽  
Nude Mice ◽  
Demineralized Bone Matrix ◽  
Platelet Rich Plasma ◽  
Bone Matrix ◽  
Demineralized Bone

Paper # 92: Demineralized Bone Matrix and Platelet-Rich Plasma for Osteochondral Defects of the Talus– An Experimental Goat Study

2011 ◽  
Vol 27 (10) ◽  
pp. e127
Author(s):  
Christiaan J.A. Van Bergen ◽  
Murat Özdemir ◽  
Gino M.M.J. Kerkhoffs ◽  
Clara M. Korstjens ◽  
Leo J. van Ruijven ◽  
...  
Keyword(s):  
Demineralized Bone Matrix ◽  
Platelet Rich Plasma ◽  
Bone Matrix ◽  
Osteochondral Defects ◽  
Demineralized Bone

Experimental Study of the Effect of Autologous Platelet-Rich Plasma on the Early Phases of Osteoinduction by Allogenic Demineralized Bone Matrix

2012 ◽  
Vol 21 (5) ◽  
pp. 399-405 ◽  
Author(s):  
Minas D. Leventis ◽  
Efstathios Eleftheriadis ◽  
Panagiota Oikonomopoulou ◽  
Helen Vavouraki ◽  
Lubna Khaldi ◽  
...  
Keyword(s):  
Experimental Study ◽  
Demineralized Bone Matrix ◽  
Platelet Rich Plasma ◽  
Bone Matrix ◽  
Autologous Platelet Rich Plasma ◽  
Early Phases ◽  
Autologous Platelet ◽  
Demineralized Bone

scholarly journals Demineralized bone matrix and platelet-rich plasma do not improve healing of osteochondral defects of the talus: an experimental goat study

2013 ◽  
Vol 21 (11) ◽  
pp. 1746-1754 ◽  
Author(s):  
C.J.A. van Bergen ◽  
G.M.M.J. Kerkhoffs ◽  
M. Özdemir ◽  
C.M. Korstjens ◽  
V. Everts ◽  
...  
Keyword(s):  
Demineralized Bone Matrix ◽  
Platelet Rich Plasma ◽  
Bone Matrix ◽  
Osteochondral Defects ◽  
Demineralized Bone

Platelet-Rich Plasma Inhibits Demineralized Bone Matrix-Induced Bone Formation in Nude Mice

2007 ◽  
Vol 89 (1) ◽  
pp. 139-147 ◽  
Author(s):  
Don M. Ranly ◽  
Christoph H. Lohmann ◽  
Domenico Andreacchio ◽  
Barbara D. Boyan ◽  
Zvi Schwartz
Keyword(s):  
Bone Formation ◽  
Nude Mice ◽  
Demineralized Bone Matrix ◽  
Platelet Rich Plasma ◽  
Bone Matrix ◽  
Demineralized Bone

scholarly journals Preliminary outcomes of the combination of demineralized bone matrix and platelet Rich plasma in the treatment of long bone non-unions

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Wei Nie ◽  
Zhaojun Wang ◽  
Jiaqing Cao ◽  
Wei Wang ◽  
Yanjie Guo ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Bone Graft ◽  
Demineralized Bone Matrix ◽  
Platelet Rich Plasma ◽  
Bone Matrix ◽  
Treatment Protocol ◽  
Long Bone ◽  
Significant Difference ◽  
Bony Healing ◽  
Demineralized Bone

Abstract Background A variety of bone graft substitutes have been introduced into the treatment of bone non-unions. However, clinical outcomes from current evidences are various and conflicting. This study aimed to present the preliminary outcomes of a treatment protocol in which the combination of demineralized bone matrix (DBM) and platelet rich plasma (PRP) was used as a bone graft substitute for long bone non-unions. Methods Data of this retrospective study were reviewed and collected from a consecutive case series involving 43 patients who presented with a long bone non-union and were treated in our department from October 2018 to May 2019. The combination of DMB and PRP was applied as a bone defect filler in 16 patients, whilst the other 27 patients were treated with iliac bone autografting. Patients’ demographics, postoperative complications and the result of bone union were compared and evaluated. Results The demographic data between the two groups were comparable. No significant difference was found with regard to the incidence of postoperative complications. No graft rejection, heterotopic ossification or other complications were noted. The distribution of bony healing time was rather scattered but did not differ significantly between the groups (7.533 ± 3.357 months vs. 6.625 ± 2.516 months; P=0.341). Union was identified radiographically in 15 of 16 patients in the DBM+PRP group and in 24 of 27 patients in autograft group. Conclusions The present study identified that low incidence of postoperative complications and satisfactory bony healing rate could be achieved in the treatment of long bone non-unions augmented with the combination of DBM and PRP. Although these findings might indicate the promising future of this treatment protocol, larger and higher quality studies should also be executed to assess its routine use.

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